Plaque-neutralizing antibody to BA.2.12.1, BA.4 and BA.5 in individuals with three doses of BioNTech or CoronaVac vaccines, natural infection and breakthrough infectionArticle Published on 2022-11-012022-11-15 Journal: Journal of Clinical Virology [Category] SARS, 변종, 진단, 치료기술, [키워드] antibody Antibody neutralization Antibody titre B.1.1.529 BNT162b2 booster Breakthrough infection convalescent CoronaVac COVID-19 detectable dose elicited geometric GMT Immune escape individual Infection less natural infection neutralization neutralizing antibody Neutralizing antibody response of BNT162b2 omicron Omicron, Neutralization plaque reduction neutralization PRNT reduction relative SARS-CoV-2 susceptible Transmissibility vaccinated individual vaccination Vaccine Vaccines virus viruses VoC wild- type WT virus [DOI] 10.1016/j.jcv.2022.105273 PMC 바로가기
Comparative effectiveness of neutralising monoclonal antibodies in high risk COVID-19 patients: a Bayesian network meta-analysisArticle Published on 2022-10-202022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), meta-analysis, SARS, 변종, 진단, [키워드] absolute reduction article baseline Bayesian comparable Comparative COVID-19 Effect effective Effectiveness Efficacy Evidence expected generalisability healthcare high risk hospitalisation ICU admission identify individual infected individual infected with SARS-CoV-2 invasive ventilation moderate monoclonal antibody Mortality network Network meta-analysis neutralising outcome Pairwise comparison patient population patients patients treated Placebo predict Rate RCT reaction reduce mortality reducing reduction in relative risk risk reduction serious AE severe COVID-19 statistically significant reduction systematic review therapy treatment effect vaccination variant [DOI] 10.1038/s41598-022-22431-6 PMC 바로가기
In vitro testing of salt coating of fabrics as a potential antiviral agent in reusable face masksArticle Published on 2022-10-112022-11-15 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 치료제, [키워드] added airway Antiviral cloth mask cloth masks collected conditions coronavirus disease COVID-19 cultures dependent on dilutions distribution Effectiveness eight epithelia epithelial evaluated Face mask Face masks H3N2 handling incubated mandatory Masks pandemic protocol quantified reduced relative remained risk Sodium chloride tested turn viral replication virus particle virus replication wearing face mask [DOI] 10.1038/s41598-022-21442-7 PMC 바로가기
Estimating SARS-CoV-2 variant fitness and the impact of interventions in England using statistical and geo-spatial agent-based models통계 및 지리 공간 에이전트 기반 모델을 사용하여 SARS-CoV-2 변종 적합도 및 영국에서의 개입 영향 추정Article Published on 2022-10-032022-09-11 Journal: Philosophical transactions. Series A, Mathematical [Category] COVID19(2023년), SARS, 변종, [키워드] agent agent-based model Alpha B.1.1.7 B.1.177 death distribution dominant variant effective England Epidemics estimate Evolution example geo-spatial model Intervention Lineage lockdown lockdowns prevented relative reopening replaced REPLACED BY Reproduction number robustness SARS-CoV-2 SARS-CoV-2 epidemic SARS-CoV-2 variant Spread statistical statistical model the epidemic Transmissibility vaccination Vaccinations variant variants Variation Viral variants virus variants [DOI] 10.1098/rsta.2021.0304 PMC 바로가기 [Article Type] Article
Potential pitfalls in analysing a SARS-CoV-2 RT-PCR assay and how to standardise data interpretationSARS-CoV-2 RT-PCR 분석 및 데이터 해석을 표준화하는 방법 분석의 잠재적 함정Article Published on 2022-10-012022-09-11 Journal: Journal of virological methods [Category] COVID19(2023년), SARS, 치료기술, [키워드] addition analysed Applied Biosystem Audit automated baseline Baseline threshold carried complex data interpretation determine Diagnostics.ai Frequency implementation in some increase in Interpretation introduced investigated Laboratory manual intervention Patient PCR positive result Potential processed produced provide Real-time PCR real-time RT-PCR relative Relative threshold RT-PCR RT-PCR kit RT-PCR kits SARS-CoV-2 SARS-CoV-2 RT-PCR solution tested thermocyclers threshold time-consuming virus detection was determined [DOI] 10.1016/j.jviromet.2022.114589 PMC 바로가기 [Article Type] Article
Diet-Induced Obesity and NASH Impair Disease Recovery in SARS-CoV-2-Infected Golden HamstersArticle Published on 2022-09-172022-11-15 Journal: Viruses [Category] SARS, 진단, [키워드] angiotensin-converting enzyme 2 Blood controls coronavirus disease Coronavirus disease 2019 COVID-19 days post-infection disease early stage Efficacy exhibited favor fibrosis form hamster hamsters hepatocyte ballooning impair induce infected with SARS-CoV-2 Infection Inflammation Inflammatory cytokines less liver Liver fibrosis liver steatosis long-lasting Lung inflammation lung viral load mechanism NASH non-alcoholic steatohepatitis obese obese patient obesity pathophysiologic Patient pulmonary fibrosis relative replicate SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected hamsters Serum level severity of COVID-19 steatohepatitis sustained systemic inflammation the SARS-CoV-2 Treatment weight loss [DOI] 10.3390/v14092067 PMC 바로가기
Relative Effectiveness of COVID-19 Vaccination in Healthcare Workers: 3-Dose Versus 2-Dose VaccinationArticle Published on 2022-09-052022-11-16 Journal: Journal of Korean medical science [Category] SARS, 변종, [키워드] 1:1 acute respiratory syndrome Analysis booster booster vaccination case-control study conducted controls coronavirus COVID-19 cross-reactive dose Effectiveness elapsed evade evaluate expected healthcare worker Immunity moderate mRNA vaccine Omicron variant positive relative SARS-CoV-2 SARS-CoV-2 test the vaccine vaccination vaccine effectiveness vaccine immunity [DOI] 10.3346/jkms.2022.37.e267 PMC 바로가기
Relative effectiveness of booster vs. 2-dose mRNA Covid-19 vaccination in the Veterans Health Administration: Self-controlled risk interval analysis재향 군인 보건국에서 부스터 대 2-용량 mRNA 코비드-19 백신 접종의 상대적 효과: 자가 통제 위험 간격 분석Article Published on 2022-08-052022-09-11 Journal: Vaccine [Category] COVID19(2023년), SARS, 변종, [키워드] (Maximum 6): Covid-19 age Analysis Antigen approach booster booster vaccination calculate calculated conducted confounders Delta effective Effectiveness exposure Gain groups health administration identify Immunity individual Logistic regression main analysis maximum mRNA odds of infection Odds ratio Odds ratios omicron Omicron variants positive positive PCR Positive test predominant relative risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 test Self-controlled case series Sensitivity analyses sensitivity analysis Stratification Study design vaccination Vaccine vaccine effectiveness variant veteran warehouse [DOI] 10.1016/j.vaccine.2022.06.047 PMC 바로가기 [Article Type] Article
The durability of natural infection and vaccine-induced immunity against future infection by SARS-CoV-2SARS-CoV-2에 의한 미래 감염에 대한 자연 감염 및 백신 유도 면역의 내구성Comparative Study Published on 2022-08-022022-09-12 Journal: Proceedings of the National Academy of Sciences of [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Ad26.COV2.S Analysis anti-S IgG antibody Antibody Response applied BNT162b2 booster vaccination Breakthrough infection ChAdOx1 conditions COVID-19 distribution elicited Endemic evaluated exceeded expected future infection IgG Immunity Immunoglobulin Infection knowledge likelihood median Messenger RNA Moderna mRNA mRNA-1273 natural infection Oxford-AstraZeneca pandemic parameter peak Pfizer-BioNTech public health Quantitative relative SARS-CoV-2 trajectory vaccination Vaccine Vaccine-induced immunity vaccine-mediated immunity Viral vector vaccine [DOI] 10.1073/pnas.2204336119 PMC 바로가기 [Article Type] Comparative Study
The comparative effectiveness of COVID-19 monoclonal antibodies: A learning health system randomized clinical trialRandomized Controlled Trial Published on 2022-08-012022-10-05 Journal: Contemporary clinical trials [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] 95% CI adjusted odds ratio age Analysis antibody authorization Bayesian COVID-19 criteria death decrease defined Effectiveness Emergency enrolled equivalence funding Government Health health system Hospitalization inferiority IQR Local mAb median Mild moderate Moderate COVID-19 monoclonal neutralize Odds ratio outcome Patient Placebo Platform trial posterior probability Probability provided random randomized clinical trial Registered relative reported SARS-CoV-2 Sex statistical Treatment Trial [DOI] 10.1016/j.cct.2022.106822 PMC 바로가기 [Article Type] Randomized Controlled Trial