Retrospective analysis of SARS-CoV-2 omicron invasion over delta in French regions in 2021-22: a status-based multi-variant modelArticle Published on 2022-11-032022-11-16 Journal: BMC Infectious Diseases [Category] SARS, 변종, [키워드] affecting Analysis approach average baseline level carried caused circulation conducted cross deaths disease epidemiological events expressed France French Generation time globe heterogeneity immunized incidence Invasion investigated knowledge Multi-variant model omicron outbreak parameter rapidly spreading disease Region regions replaced reported SARS-CoV-2 SARS-COV-2 infection Spread Transmissibility transmission potential Uncertainty variant [DOI] 10.1186/s12879-022-07821-5 PMC 바로가기
Genomic and epidemiologic surveillance of SARS-CoV-2 in Southern Brazil and identification of a new Omicron-L452R sublineageArticle Published on 2022-11-012022-11-16 Journal: Virus research [Category] SARS, 변종, 유전자 메커니즘, [키워드] Amino acid B.1.1.529 Brazil Characteristics COVID-19 cases delta variant dominant Epidemiologic surveillance epidemiological data Genetic increase in information knowledge mutated Mutation mutational scanning omicron pandemic replaced Research resulting S:L452R SARS-CoV-2 the SARS-CoV-2 variant VoC VOC. [DOI] 10.1016/j.virusres.2022.198907 PMC 바로가기
Viral load of SARS-CoV-2 Omicron is not high despite its high infectivityArticle Published on 2022-11-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome caused cell receptor coronavirus coronavirus disease COVID-19 Delta delta variant examined Factors Genotype genotyping Immune escape median melting curve analysis nasopharyngeal no significant difference omicron Omicron variant Patient PCR performed polymerase chain Quantitative replaced SARS-CoV-2 Sequencing Spread Transmissibility two group variant Viral load virus [DOI] 10.1002/jmv.27974 PMC 바로가기
Time Series Analysis of SARS-CoV-2 Genomes and Correlations among Highly Prevalent MutationsArticle Published on 2022-10-262022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome Analysis arising caused characterized Cluster Clustering computational tool contribute coronavirus correlated correlation correlation coefficient COVID-19 Deleterious Effect effort Evolution Frequency Genome genomes Hierarchical hierarchical clustering identify imperative in viral Meta-analysis Mutation mutations negative correlation Neutral NSP2 Nsp3 nucleotide ORF3a protein P323L pandemic Pearson Pearson correlation performed positive Protein protein dynamics. Q57H RdRP replaced RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 evolution SARS-CoV-2 genome SARS-CoV-2 genomic sequence SARS-CoV-2 isolate SARS-CoV-2 sequences Scientific community Sery shown similarity stabilizing effect statistical T85I These data time UTR viral evolution viral genomes viral pathogenesis viral replication viral strains wild type wild-type [DOI] 10.1128/spectrum.01219-22 PMC 바로가기
Effectiveness of Monovalent mRNA Vaccines Against COVID-19-Associated Hospitalization Among Immunocompetent Adults During BA.1/BA.2 and BA.4/BA.5 Predominant Periods of SARS-CoV-2 Omicron Variant in the United States – IVY Network, 18 States, December 26, 2021-August 31, 2022Article Published on 2022-10-212022-11-16 Journal: Morbidity and Mortality Weekly Report [Category] COVID19(2023년), SARS, 변종, [키워드] accounted Against B.1.1.529 booster dose category COVID-19 vaccine dose Effectiveness eligible adult estimate expected Hospitalization Immunity immunocompetent adult immunogenic include Infection Interpretation Lineage lineages majority monovalent mRNA mRNA component mRNA COVID-19 vaccine mRNA vaccine network omicron overlapped Period predominant Prevent protection receive reduce replaced SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain second dose the United State vaccination Vaccine Vaccine-induced immunity variant waned [DOI] 10.15585/mmwr.mm7142a3 PMC 바로가기
Impact of Early Pandemic SARS-CoV-2 Lineages Replacement with the Variant of Concern P.1 (Gamma) in Western Bahia, BrazilArticle Published on 2022-10-212022-11-16 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] addition affected age Brazil caused concern COVID-19 COVID-19 case COVID-19 cases death deaths disease epidemiological fluctuation Gamma Gender genetic variants Host Impact individual men nasopharynx P.1 pandemic Patient replaced replacement SARS-CoV-2 SARS-CoV-2 lineage significant increase study period symptomatic the patient the SARS-CoV-2 variant variant of concern Viral load VoC [DOI] 10.3390/v14102314 PMC 바로가기
Methicillin-resistant staphylococcus aureus nosocomial infection has a distinct epidemiological position and acts as a marker for overall hospital-acquired infection trendsArticle Published on 2022-10-112022-11-15 Journal: Scientific Reports [Category] 바이오마커, [키워드] Analysis Biomarker Care Control COVID-19 pandemic dataset disease Diseases drug-resistant Efficacy epidemiological epidemiologist HAI healthcare hospital hospitalized patients Infection lack Lower marker microbe MRSA Nosocomial infection Nosocomial infections outbreak pathogen Patient prevented reduced replaced Staphylococcus aureus Stress threshold unique USA [DOI] 10.1038/s41598-022-21300-6 PMC 바로가기
A RT-qPCR system using a degenerate probe for specific identification and differentiation of SARS-CoV-2 Omicron (B.1.1.529) variants of concernArticle Published on 2022-10-052022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] B.1.1.529 B.1.617.2 circulating complement degenerate Delta delta variant detect dominant Inclusion introduced L452R Mutation offer omicron pathogenic platform primer probe probe sequence probes replaced resource RT-qPCR RT-qPCRs SARS-CoV-2 SARS-CoV-2 variant Sequencing Spread Surveillance the spike protein variant variants variants of concern whole genome [DOI] 10.1371/journal.pone.0274889 PMC 바로가기
Estimating SARS-CoV-2 variant fitness and the impact of interventions in England using statistical and geo-spatial agent-based models통계 및 지리 공간 에이전트 기반 모델을 사용하여 SARS-CoV-2 변종 적합도 및 영국에서의 개입 영향 추정Article Published on 2022-10-032022-09-11 Journal: Philosophical transactions. Series A, Mathematical [Category] COVID19(2023년), SARS, 변종, [키워드] agent agent-based model Alpha B.1.1.7 B.1.177 death distribution dominant variant effective England Epidemics estimate Evolution example geo-spatial model Intervention Lineage lockdown lockdowns prevented relative reopening replaced REPLACED BY Reproduction number robustness SARS-CoV-2 SARS-CoV-2 epidemic SARS-CoV-2 variant Spread statistical statistical model the epidemic Transmissibility vaccination Vaccinations variant variants Variation Viral variants virus variants [DOI] 10.1098/rsta.2021.0304 PMC 바로가기 [Article Type] Article
Expanding the antiviral potential of the mosquito lipid-transfer protein AEG12 against SARS-CoV-2 using hydrophobic antiviral ligandsArticle Published on 2022-10-012022-11-15 Journal: Febs Letters [Category] COVID19(2023년), SARS, 치료제, [키워드] Antiviral antiviral activity antiviral therapeutics bind Cell complexes Compound cytotoxicity drug delivery enveloped virus fatty Fatty acid hydrophobic inhibitors Ligand ligands lipid-binding protein mechanism membrane membrane disruption. membranes modulated neutralize Protein replaced resulting SARS-CoV-2 Therapeutic compounds unsaturated viruses [DOI] 10.1002/1873-3468.14456 PMC 바로가기