Exploring TRIM proteins’ role in antiviral defense against influenza A virus and respiratory coronavirusesarticle Published on 2024-07-152024-09-05 Journal: Frontiers in Cellular and Infection Microbiology [Category] update2024, [키워드] influenza A virus Innate immunity Respiratory Coronavirus TRIM proteins viral components [DOI] 10.3389/fcimb.2024.1420854 PMC 바로가기 [Article Type] article
Nitazoxanide and COVID-19: A reviewArticle Published on 2022-11-012022-11-15 Journal: Molecular biology reports [Category] SARS, 치료제, [키워드] Activation acute lung injury acute respiratory distress acute respiratory distress syndrome addition Anti-inflammatory anti-parasitic drug anti-SARS-CoV-2 Antiviral antiviral activity antiviral property ARDS autophagic cause cell death clinical trial Coronavirus disease 2019 COVID-19 Cytokine storm Cytokines distress drug effective finding IFN immunological in silico in vitro study Infection inflammatory disorders inflammatory reaction inhibit Innate immunity interferon lung mammalian mitigate Multi-organ damage nitazoxanide oxidative stress pathogenesis of SARS-CoV-2 pro-inflammatory cytokines Prospective Study Protozoa Rapamycin reduce Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 infections severe cases syndrome therapy Treatment triggered viral infections Viral pneumonia [DOI] 10.1007/s11033-022-07822-2 PMC 바로가기
Viral load may impact the diagnostic performance of nasal swabs in nucleic acid amplification test and quantitative antigen test for SARS-CoV-2 detectionArticle Published on 2022-11-012022-11-15 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 치료기술, [키워드] amplification Antigen automated collected cycle threshold detect diagnostic early stage evaluated healthcare Measures NAAT nasal swab nasal swabs Nasopharyngeal swab nasopharyngeal swabs negative correlation nine NPs nucleic acid amplification nucleic acid amplification test patients with COVID-19 positive Quantitative Quantitative SARS-CoV-2 antigen test Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 detection significantly significantly higher significantly lower symptom onset tested Viral load were used [DOI] 10.1016/j.jiac.2022.07.023 PMC 바로가기
Cardiac megakaryocytes in SARS-CoV-2-positive autopsiesArticle Published on 2022-11-012022-11-15 Journal: Histopathology [Category] SARS, 치료기술, [키워드] addition Autopsies Autopsy average cardiac Cell Cohort Comorbidity correlated Course COVID-19 COVID-19 cohort evaluated groups Increasing Infection inflammatory markers Inflammatory response Laboratory management megakaryocytes nonspecific parameter Patient performed Platelet Platelets precursor pulmonary disease Pulmonary emboli reported Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2-positive patient selected severe COVID-19 significantly higher statistically significant supported the disease thromboembolic thrombotic complication viral infections were assessed [DOI] 10.1111/his.14734 PMC 바로가기
SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived CellsArticle Published on 2022-10-262022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] activate Activation activities activity acute respiratory syndrome betacoronaviruses Cell cellular change coronavirus country Critical death downstream Endoplasmic reticulum enzyme ER stress examined expression of gene functions Gene Expression HCoV-OC43 Host host cell host cells host immune system Human human cell human cells imperative individual induce infect Infection inhibit interact IRE1α pathway less limit MERS-CoV MHV Middle East molecular mechanism mRNA murine OC43 Other other coronavirus pathway Prevent processed Replication required Respiratory Coronavirus respiratory syndrome coronavirus Reticulum RNase SARS-CoV SARS-CoV-2 SARS-COV-2 infection severe respiratory disease signaling pathway similarity splice Spread Stress tested the interferon transcription factor Trigger unfolded protein response UPR Vaccine viral replication virus XBP1 [DOI] 10.1128/mbio.02415-22 PMC 바로가기
Adverse events and humoral response after two doses of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) mRNA vaccine in the hospital personnel of a cardiopulmonary tertiary-care centerArticle Published on 2022-10-012022-11-15 Journal: Infection Control and Hospital Epidemiology [Category] COVID19(2023년), SARS, 진단, [키워드] Adverse Cardiopulmonary dose event hospital humoral mRNA vaccine Respiratory Coronavirus SARS-CoV-2 virus [DOI] 10.1017/ice.2021.321 PMC 바로가기
Use of whole-genome sequencing to investigate a cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in emergency department personnelArticle Published on 2022-10-012022-11-15 Journal: Infection Control and Hospital Epidemiology [Category] COVID19(2023년), SARS, 진단, [키워드] acquisition acute respiratory syndrome Cluster coronavirus healthcare personnel Infection outbreak raised Respiratory Coronavirus SARS-CoV-2 Sequencing Transmission transmission cluster virus whole-genome sequencing [DOI] 10.1017/ice.2021.208 PMC 바로가기
Unexpected details regarding nosocomial transmission revealed by whole-genome sequencing of severe acute respiratory coronavirus virus 2 (SARS-CoV-2)Article Published on 2022-10-012022-11-16 Journal: Infection Control and Hospital Epidemiology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] age Analysis clade Clinical characteristics cohort study collected coronavirus disease COVID-19 Deceased died epidemiological epidemiological data evaluate event Genetic HCW HCWs healthcare worker hospital identify indicated Infection prevention knowledge male measure Measures mechanism median medical records nasopharyngeal sample nosocomial nosocomial COVID-19 Nosocomial infection NPs outbreak outcome Patient patients performed Phylogenetic analysis positive provided Respiratory Coronavirus RNA SARS-CoV-2 selected significantly higher subclade supported Transmission viral clade virus WGS whole-genome sequencing [DOI] 10.1017/ice.2021.374 PMC 바로가기
The challenges of education in a continental country in the face of new severe acute respiratory coronavirus virus 2 (SARS-CoV-2) variant circulationArticle Published on 2022-10-012022-11-16 Journal: Infection Control and Hospital Epidemiology [Category] COVID19(2023년), SARS, 변종, [키워드] circulation country Respiratory Coronavirus SARS-CoV-2 variant virus [DOI] 10.1017/ice.2021.291 PMC 바로가기
Curbing the Delta Surge: Clinical Outcomes After Treatment With Bamlanivimab-Etesevimab, Casirivimab-Imdevimab, or Sotrovimab for Mild to Moderate Coronavirus Disease 2019Article Published on 2022-09-012022-11-15 Journal: Mayo Clinic proceedings [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Admission B.1.617.2 Care clinical Clinical outcome Cohort comparable coronavirus disease COVID-19 COVID-19 vaccination death Delta high-risk patient Hospitalization intensive care large cohort Mild moderate Moderate COVID-19 Mortality outcome oxygen supplementation Patient patients treated Rate Respiratory Coronavirus Retrospective study SARS-CoV-2 severe disease significantly lower Sotrovimab the SARS-CoV-2 Treatment were assessed [DOI] 10.1016/j.mayocp.2022.06.015 PMC 바로가기