Detection of viable SARS-CoV-2 in deep respiratory specimens despite negative nasopharyngeal SARS-CoV-2 RT-PCR: occult COVID-19 as an unsuspected cause of pulmonary infiltrates in immunocompromised patientsCase report Published on 2022-08-232022-10-05 Journal: IDCases [Category] 진단, 치료기술, [키워드] anti-CD20 Antigen Antiviral treatment BAL Bronchoalveolar lavage changes clearance COVID-19 COVID-19 infection demonstrated detection diagnosed Diagnosis etiology highlight Immunocompromise Immunocompromised patient Immunocompromised patients immunohistochemistry invasive Isolation limit lung lung parenchyma lung tissue nasopharyngeal occult Occult COVID-19 pandemic parenchymal Patient persistence Precaution Primary infection Prolonged pulmonary infiltrate Relapse repeated Replication reported resolved respiratory specimen rituximab SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2 virus specimens spike-protein suggested Viral antigen viral persistence virus [DOI] 10.1016/j.idcr.2022.e01611 [Article Type] Case report
Tracheal Aspirate and Bronchoalveolar Lavage as Potential Specimen Types for COVID-19 Testing Using the Cepheid Xpert Xpress SARS-CoV-2/Flu/RSVCepheid Xpert Xpress SARS-CoV-2/Flu/RSV를 사용한 COVID-19 검사를 위한 잠재적 표본 유형으로서의 기관 흡인 및 기관지폐포 세척Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, 치료제, [키워드] addition anticipated approved aspirate BAL Bronchoalveolar lavage bronchoalveolar lavage sample bronchoalveolar lavage samples Cepheid community transmission COVID-19 criteria Cycle threshold values Diagnosis diagnostic test evaluated Evidence help hospital implication Influenza influenza A influenza B lab lavage Lower respiratory tract lower respiratory tract specimen management multiplex overcome Patient PCR test performance platform point of care positive Potential Precision provide Rapid diagnostic test reproducibility respiratory respiratory specimen respiratory syncytial virus SARS-CoV-2 SARS-CoV-2 detection specimen specimens target tested Testing the SARS-CoV-2 tracheal Type upper respiratory tract Xpert Xpress SARS-CoV-2 assay [DOI] 10.1128/spectrum.00399-22 PMC 바로가기 [Article Type] Article
Detection of SARS-CoV-2 Variants by Multiple Diagnostic Assays Second RESUBMISSION JCV-D-21-00675R2다중 진단 분석에 의한 SARS-CoV-2 변이체 감지 두 번째 RESUBMISSION JCV-D-21-00675R2Article Published on 2022-06-012022-09-11 Journal: Journal of Clinical Virology [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] being center circulating concern Ct values demonstrated detect detection diagnostic Diagnostic method diagnostic methods disease severity Evolution examined immune evasion imperative investigated Laboratory material molecular Molecular diagnosis MONITOR much higher Multiple New York other variant platform provided public health representing reproducibility respiratory specimen SARS-CoV-2 SARS-CoV-2 variants second selected sensitivity sequence specimen state submitted targets tested the SARS-CoV-2 variant Variant Being Monitored variant of concern variants virus virus transmissibility VoC [DOI] 10.1016/j.jcv.2022.105160 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severityArticle Published on 2022-05-192022-10-04 Journal: Nature Communications [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, 치료법, 치료제, [키워드] Adaptive immunity Affect Blood cellular COVID-19 COVID-19 patients cytokine response Dexamethasone disease severity domain Hospital stay hospitalized COVID-19 patients humoral Humoral response IFN-α2 IgA IgG IgM IgM and IgG IL-12p70 immune immune component immune parameter immune response immunopathology infection with SARS-CoV-2 Inflammation mechanism neutralization Neutrophils not affect Peripheral blood plasma Prognosis respiratory respiratory sample Respiratory samples respiratory specimen respiratory specimens respiratory tract SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 neutralization activity Seroconversion sputum subset therapy Treatment viral infection [DOI] 10.1038/s41467-022-30088-y PMC 바로가기 [Article Type] Article
Critically ill patients with COVID-19 show lung fungal dysbiosis with reduced microbial diversity in patients colonized with Candida spp.Research article Published on 2022-04-012022-10-05 Journal: International Journal of Infectious Diseases [Category] 바이오마커, [키워드] acute respiratory disease syndrome acute respiratory distress addition Affect Amplicon sequencing ARDS Ascomycota Aspergillus Bacterial Candida Cell characterized contribute corticosteroid therapy COVID-19 COVID-19 pandemic Critically ill patient decrease Dysbiosis fungal galactomannan Illumina Miseq Infection Lower respiratory tract lung microbial Microbiome Mycobiome Next-generation sequencing NGS Patient patients with COVID-19 patients without COVID-19 performed Phylogenetic platform Pneumonia positive reduced respiratory specimen Result spacer specimen syndrome transcribed with COVID-19 [DOI] 10.1016/j.ijid.2022.02.011 [Article Type] Research article
Postvaccination infections among staff of a tertiary care hospital after vaccination with severe acute respiratory syndrome coronavirus 2 vector and mRNA-based vaccines중증급성호흡기증후군 코로나바이러스 2 벡터 및 mRNA 기반 백신 접종 후 3차 병원 직원 중 접종 후 감염Observational Study Published on 2022-04-012022-09-11 Journal: Clinical microbiology and infection : the official [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered administration Alpha variant analysed Antigen B.1.1.7 B.1.351 B.1.617.2 Beta Beta variant BNT162b2 Breakthrough infection breakthrough infections Care ChAdOx1 ChAdOx1-S cohort study coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 death defined Delta delta variant demographic data dose effective first dose follow-up period hazard ratio hazard ratios hospital Hospital employees Hospitalization incidence Infection mRNA mRNA-based vaccine mRNA-based vaccine. not differ Observational cohort study Participants positive PCR positive PCR test postvaccination Postvaccination infection reported respiratory specimen retrospective retrospective observational cohort study RNA SARS-CoV-2 SARS-CoV-2 vaccine second dose severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 specimen vaccination Vaccination Status Vaccine vaccine dose vaccine doses variant Vector-based vaccine Viral load virus variants [DOI] 10.1016/j.cmi.2021.11.023 PMC 바로가기 [Article Type] Observational Study
Evidence of SARS-CoV-2 symptomatic reinfection in four healthcare professionals from the same hospital despite the presence of antibodies항체가 있음에도 불구하고 같은 병원의 의료 전문가 4명에서 SARS-CoV-2 증상 재감염의 증거Article Published on 2022-04-012022-09-11 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] Chain Reaction collected conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic disease event Evidence evidence of exposure to Follow-up Habib Bourguiba HCWs Healthcare professional healthcare worker Healthcare workers hospital IgG IgM Immune status individual Infection initial isolate natural infection occurred Patient patients polymerase chain reaction positive presence of antibody protective immunity public health Quantitative raising ranged Reinfection reported respiratory respiratory specimen reverse transcriptase reverse transcriptase-polymerase chain reaction RT-PCR SARS-CoV-2 SARS-CoV-2 variant serology specimen Symptom symptomatic the patient total Ig university vaccination variants Viral viral genome viral genomes Viral RNA viral RNAs viral sample viral samples viral sequence viral sequences were used whole-genome sequencing [DOI] 10.1016/j.ijid.2022.01.006 PMC 바로가기 [Article Type] Article
Severe neonatal COVID-19: Challenges in management and therapeutic approach중증 신생아 COVID-19: 관리 및 치료적 접근의 도전Case Reports Published on 2022-04-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Adults age Bacterial biological samples breathing challenge Chest computed tomography chest X-rays children clearance clinical manifestation clinical manifestations complications Computed tomography consolidations contributed coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critical case critical cases demonstrated enoxaparin Enterobacter etiological agent immunomodulation increasingly Infant Infants intensive care interstitial interstitial pneumonia less life-threatening lung management mechanical ventilation mounted multidrug-resistant Neonatal Neonatal COVID-19 neonatal sepsis Neonate Neonates Older reported respiratory infection respiratory specimen respiratory specimens SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 RNA Sepsis serological test Serological tests Severe acute respiratory syndrome severe acute respiratory syndrome 2. severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Severe case steroid Steroids stools sustained Therapeutic approach viral replication Work of breathing [DOI] 10.1002/jmv.27472 PMC 바로가기 [Article Type] Case Reports
Public screening for COVID-19 in Wuhan, China and beware of the antibody positive in women and tumor patients중국 우한시 코로나19 공개검진, 여성·종양환자 항체양성 주의Article Published on 2022-04-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed antibody Antibody testing Cancer clinical clinical implications coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 diagnosis COVID-19 pandemic Early detection female female. Government groups Health health emergency help hospital IgG IgM Immunoglobulin Immunoglobulin G immunoglobulin M implication Intervention key factor male measure Molecular assay molecular assays Novel coronavirus novel coronavirus disease nucleic acid outcome Patient patients with COVID-19 polymerase chain positive Prevent Public reference standard respiratory respiratory specimen respiratory specimens reverse transcriptase Reverse transcriptase polymerase chain reaction SARS-CoV-2 severe acute respiratory syndrome Coronavirus significantly higher specimen transcriptase Tumor university women Wuhan Wuhan, China [DOI] 10.1002/jmv.27483 PMC 바로가기 [Article Type] Article
COVID-19 Associated Pulmonary Aspergillosis: Diagnostic Performance, Fungal Epidemiology and Antifungal SusceptibilityArticle Published on 2022-01-182022-10-30 Journal: Journal of Fungi [Category] COVID-19, [키워드] Antifungal antifungal susceptibility testing Antifungal treatment aspergillosis Aspergillus Aspergillus flavus Aspergillus fumigatus Aspergillus nidulans Aspergillus niger BAL Bronchoalveolar lavage changes in Cohort contribute Coronavirus disease 2019 coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA) COVID-19 Culture Diagnosis diagnostic tests Epidemiology fungal fungal diagnosis highlight hospital ICU patient incidence increased mortality involved majority marker Microscopy performance positive sample pulmonary raise respiratory specimen serum suffered treated [DOI] 10.3390/jof8020093 PMC 바로가기 [Article Type] Article