A Generative Pretrained Transformer (GPT)–Powered Chatbot as a Simulated Patient to Practice History Taking: Prospective, Mixed Methods StudyOriginal Paper Published on 2024-01-162024-09-05 Journal: JMIR Medical Education [Category] update2024, [키워드] answer answers artificial intelligence chatbot chatbots ChatGPT Conversational Agent conversational agents documentation generative pretrained transformer GPT history history taking Human computer human machine interactive medical education natural language processing NLP response responses Satisfaction simulated simulated patient Simulation Simulations Usability [DOI] 10.2196/53961 PMC 바로가기 [Article Type] Original Paper
Environment and COVID-19 incidence: A critical reviewReview article Published on 2023-02-012022-10-05 Journal: Journal of environmental sciences (China) [Category] COVID19(2023년), SARS, 변종, [키워드] Affect article caused coronavirus disease COVID-19 COVID-19 incidence COVID-19 pandemic COVID-19 transmission Critical Depression Effect Environment environmental factor environmental factors Factor Future Health heterogeneity Human environment Impact Interaction investigated lockdown Natural environment pandemic peer-reviewed Perspective Research responses SARS-CoV-2 survival [DOI] 10.1016/j.jes.2022.02.016 [Article Type] Review article
Memory B cell responses to Omicron subvariants after SARS-CoV-2 mRNA breakthrough infection in humansArticle Published on 2022-12-052022-11-15 Journal: The Journal of Experimental Medicine [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] antibodies antibody Antigen antigenic breadth Breakthrough infection Cell comparable Delta develop dose Effect elicit Frequency Human increase increases in individual Infection memory memory B memory B cell memory B cells memory response Memory responses mRNA mRNA vaccine omicron plasma antibody receive response responses SARS-CoV-2 severe COVID-19 [DOI] 10.1084/jem.20221006 PMC 바로가기
Safety and immunogenicity of inactivated SARS-CoV-2 vaccines in people living with HIVHIV 보균자에서 비활성화된 SARS-CoV-2 백신의 안전성 및 면역원성Observational Study Published on 2022-12-012022-09-12 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 임상, 진단, [키워드] adverse event age Analysis binding domain booster dose CD4 CD4 count CD4 counts Cell COVID-19 declined Efficacy enrolled evaluated Factor Frequency Gender geometric GMT healthy control healthy controls HIV humoral humoral immune response IgG immune immune response Immunocompromised in both groups inactivated Inactivated vaccine less MBC memory B occurred Patient PLWH predicted prospective observational study reduced remained reported response responses robust Safety SARS-CoV-2 SARS-CoV-2 vaccine Serious Adverse Event Seven significantly vaccination Viral load with HIV [DOI] 10.1080/22221751.2022.2059401 PMC 바로가기 [Article Type] Observational Study
3D Ex vivo tissue platforms to investigate the early phases of influenza a virus- and SARS-CoV-2-induced respiratory diseasesArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 신약개발, 진단, 치료제, [키워드] animal model animal models Antiviral Cell Cell culture comparable consequence Drug repurposing drug target early phase Ex vivo ex vivo infection Ex vivo infection model Health Host human lung IAV in vitro Infection Inflammatory cytokine Influenza influenza A virus Influenza virus Innate immunity interferon interferon response Intervention introduced lung tissue morbidity and mortality murine outbreak pathophysiological pharmacological platform Respiratory disease respiratory viruses responses SARS-CoV-2 therapy tissue Treatment viral infection viral life cycle viral replication virus while [DOI] 10.1080/22221751.2022.2117101 PMC 바로가기
Targeting SARS-CoV-2 papain-like protease in the postvaccine eraArticle Published on 2022-11-012022-11-15 Journal: Trends in pharmacological sciences [Category] SARS, 치료제, [키워드] approval artificial intelligence Compound computer-aided drug design COVID-19 Critical direct-acting antiviral drug drugs expected global healthcare Host innate immune response methodology Papain-like protease PLPro Rapid responses SARS-CoV-2 SARS-CoV-2 protein Small molecules small molecules. targeting therapeutic target Vaccine viral replication waning immunity while [DOI] 10.1016/j.tips.2022.08.008 PMC 바로가기
Neutralizing antibody responses against SARS-CoV-2 in patients with plasma cell disorders who are on active treatment after two doses of mRNA vaccinationArticle Published on 2022-11-012022-11-15 Journal: European journal of haematology [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome Adults antibody Antibody Response approved BNT162b2 Cell clinically Combination coronavirus disorder dose Efficacy FDA healthy Hospitalization IgG levels increased mortality Lymphocytes majority mRNA mRNA vaccination mRNA vaccine mRNA-1273 Multiple myeloma NAb NAbs Patient plasma Plasma cell disorder Prospective Study required responses SARS CoV-2 SARS-CoV-2 therapy Treatment vaccination vaccine dose [DOI] 10.1111/ejh.13826 PMC 바로가기
Brain-computer interface to predict impulse buying behavior using functional near-infrared spectroscopyArticle Published on 2022-10-262022-11-15 Journal: Scientific Reports [Category] 바이오마커, [키워드] Accuracy Activation average Biomarker Brain Evidence functional increase interface limitation memory methodology near-infrared spectroscopy predict previous study provide reduce reported responses Support Travel vaccination against COVID-19 [DOI] 10.1038/s41598-022-22653-8 PMC 바로가기
From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22Article Published on 2022-10-212022-11-15 Journal: Cardiovascular Research [Category] 바이오마커, 유전자 메커니즘, [키워드] Anti-viral therapy approaches Atherosclerosis basic Basic science Biomarker Biomarkers Cardiac arrhythmia Cardiology cardiovascular cardiovascular system Cell Community Council COVID-19 demonstrated disease driving European extracellular vesicle Genetic polymorphism highlight Inflammation knowledge mechanism Medicine molecular molecular basis non-coding RNA pathogenic Personalized medicine Physiology Precision precision medicine Prize PROTECT Protective responses Science single-cell Society syndrome thrombotic complication Vascular [DOI] 10.1093/cvr/cvac114 PMC 바로가기
Construction and evaluation of a self-replicative RNA vaccine against SARS-CoV-2 using yellow fever virus repliconArticle Published on 2022-10-202022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, [키워드] acute respiratory syndrome antibody Antigen C57BL/6 caused cells co-expressed construction coronavirus coronavirus disease COVID-19 effective vaccine Efficacy Electroporation elicit ENCODE ENhance evaluated Fever gene encoding Host host genome immune response Immunity IMPROVE Infection Innate immunity kidney mice mRNA vaccine pandemic Protein qRT-PCR Replication replicon responses RNA RNA vaccine robust S protein expression Safe SARS-CoV-2 significantly higher single dose Specific T-cell response T-cell Response the S protein Vaccine vaccine administration vaccine platform virus [DOI] 10.1371/journal.pone.0274829 PMC 바로가기