Real-world evidence for the effectiveness and breakthrough of BNT162b2 mRNA COVID-19 vaccine at a medical center in Japan일본 의료 센터에서 BNT162b2 mRNA COVID-19 백신의 효과 및 돌파구에 대한 실제 증거Article Published on 2022-12-312022-09-11 Journal: Human vaccines & immunotherapeutics [Category] COVID19(2023년), SARS, 변종, [키워드] Asia Asian BNT162b2 BNT162b2 vaccine breakthrough COVID-19 vaccine delta variant demonstrated Effectiveness Effectiveness. Evidence evidence of hospital hygiene Infection infection control Japan measure mRNA of BNT162b2 Population populations Public hygiene Regulation required retrospective cohort study SARS-CoV-2 Spread Tokyo vaccination Vaccine variant while [DOI] 10.1080/21645515.2021.1984124 PMC 바로가기 [Article Type] Article
Covid-19 vaccination programme effectiveness against SARS-CoV-2 related infections, hospital admissions and deaths in the Apulia region of Italy: a one-year retrospective cohort studyArticle Published on 2022-11-032022-11-16 Journal: Scientific Reports [Category] SARS, 변종, [키워드] Ad26.COV2.S vaccine Alpha Apulia calculate ChAdOx1-S Cohort combined use conducted COVID-19 COVID-19 infection COVID-19 infections COVID-19 vaccination COVID-19 vaccination programme Cox regression model death deaths Delta variants dominant Effect Effectiveness Effects Electronic health record eligible estimate hazard ratio Hospital admission hospitalisation infections Italy mRNA-1273 of BNT162b2 Older outcome positive Protective reduced retrospective cohort study SARS-CoV-2 SARS-CoV-2 infections study period subject vaccination Vaccine variant variants waned were used yielding [DOI] 10.1038/s41598-022-23235-4 PMC 바로가기
Third dose of COVID-19 mRNA vaccine appears to overcome vaccine hyporesponsiveness in patients with cirrhosisArticle Published on 2022-11-012022-11-16 Journal: Journal of hepatology [Category] SARS, 변종, [키워드] 95% CI appear B.1.1.529 B.1.617.2 BNT BNT162b2 BNT162b2 mRNA booster booster dose chronic liver disease cirrhosis compensated Control control group COVD-19 COVID-19 COVID-19 in patient COVID-19 vaccines COVID-19-related death Critical dose doses General population greater hepatic decompensation hyporesponsiveness immune dysregulation liver magnitude moderate Moderate COVID-19 Moderna mRNA-1273 vaccine mRNA vaccine mRNA-1273 mRNA-1273. outcome overcome participant Patient Pfizer predominant receipt reduction in retrospective cohort study risk of infection Support symptomatic the vaccine Vaccine Vaccines variants veteran with COVID-19 [DOI] 10.1016/j.jhep.2022.07.036 PMC 바로가기
Exploratory analysis of interleukin-38 in hospitalized COVID-19 patientsArticle Published on 2022-11-012022-11-15 Journal: Immunity, Inflammation and Disease [Category] SARS, 바이오마커, [키워드] Adaptive immune response Admission age Analysis anti-inflammatory effect anti-inflammatory properties binding Biomarker cartilage CD244 CHL1 circulating Clinical data Cohort cohorts Concentration concentrations coronavirus disease correlated correlation COVID-19 COVID-19 patient COVID-19 severity disease dismutase dysregulated enzyme-linked immunosorbent exploratory fatty healthy control healthy controls healthy subjects hospital Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients IL-1 Immunoglobulin in viral increase in infections Inflammatory biomarker intensive care interleukin-38 investigated men moderate Mortality no difference outcome plasma positive correlation positively correlated progression Protein proximity extension assay recent receptor reduce retrieved retrospective cohort study retrospective cohort study. SARS-CoV-2 SERPINA12 severity shown subjects thrombocyte TNF TNFRSF9 validation cohort were measured while women [DOI] 10.1002/iid3.712 PMC 바로가기
Reinfection with SARS-CoV-2 in general population, South Korea; nationwide retrospective cohort studyArticle Published on 2022-11-012022-11-16 Journal: Journal of medical virology [Category] SARS, 변종, [키워드] analyzed Antigen conducted COVID-19 Delta dose Epidemiology General population highest Immunity infections Korean laboratory-confirmed laboratory-confirmed SARS-CoV-2 infection majority National occurred omicron performed Person polymerase chain Reinfection reinfection. retrospective cohort study SARS-CoV-2 South South Korea vaccination variants [DOI] 10.1002/jmv.28026 PMC 바로가기
Evaluation of Procalcitonin’s Utility to Predict Concomitant Bacterial Pneumonia in Critically Ill COVID-19 PatientsArticle Published on 2022-11-012022-11-15 Journal: Journal of Intensive Care Medicine [Category] 바이오마커, [키워드] Antibiotic therapy AUC Bacteremia Bacterial Bacterial infection bacterial pneumonia baseline characteristics Concomitant conducted COVID-19 creatinine Critical Critical illness Critically ill patient Culture defined determine diagnosing diagnostic ENhance evaluate group hospitalized patients ICU ICU patient identify Ill in-hospital mortality intensive care intensive care unit Mortality multivariable multivariable model no difference no significant difference offer outcome Patient PCT Pneumonia positive predict Predictive procalcitonin procalcitonin. receiver operating characteristics Regression model retrospective cohort study ROC SARS-CoV-2 secondary bacterial pneumonia serum creatinine Severe COVID-19 pneumonia Severity of disease specificity threshold utility variable vital signs was used while with COVID-19 [DOI] 10.1177/08850666221108636 PMC 바로가기
COVID-19 vaccine breakthrough infection among fully vaccinated healthcare workers in Duhok governorate, Iraqi Kurdistan: A retrospective cohort studyArticle Published on 2022-11-012022-11-16 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] association Break through infections Breakthrough infection COVID-19 COVID-19 vaccine dentist determine Duhok effective Effectiveness enrolled females fill out fully vaccination HCW HCWs healthcare healthcare worker Healthcare workers highest incidence Infection infections Iraqi Kurdistan majority male Mild moderate MOST multicenter omicron outcomes paramedics participant Pfizer polymerase chain positive postvaccination prevaccination questionnaire random respiratory retrospective cohort study risk factor SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant severity significantly the disease the vaccine Vaccine vaccine effectiveness. variant was performed [DOI] 10.1002/jmv.27985 PMC 바로가기
Clinical characteristics of COVID-19 in hospitalized children during the Omicron variant predominant periodArticle Published on 2022-11-012022-11-16 Journal: Journal of infection and chemotherapy : official j [Category] SARS, 변종, [키워드] ≥38.0 °C Admission age Characteristics children clinical Clinical characteristics clinical manifestation clinical manifestations conducted coronavirus disease COVID-19 COVID-19 patient Delta delta variant enrolled Fever Hospitalized intensive care less noninvasive olfactory dysfunction omicron Omicron variant outcome oxygen support Patient patients died pediatric predominant retrospective cohort study SARS-CoV-2 Seizure Seizures seizures. sore throat study period underlying disease variant [DOI] 10.1016/j.jiac.2022.08.004 PMC 바로가기
A retrospective cohort study of pregnancy outcomes during the pandemic period of the SARS-CoV-2 omicron variant: A single center’s experienceArticle Published on 2022-11-012022-11-16 Journal: International journal of gynaecology and obstetric [Category] COVID19(2023년), SARS, 변종, [키워드] Antenatal Infection medical intervention Obstetric Obstetric outcomes omicron outcome outcomes pandemic patients Pregnancy pregnancy. retrospective retrospective cohort study SARS-CoV-2 SARS-COV-2 infection single center Symptom the SARS-CoV-2 variant [DOI] 10.1002/ijgo.14312 PMC 바로가기
Severity of Illness Caused by Severe Acute Respiratory Syndrome Coronavirus 2 Variants of Concern in Children: A Single-Center Retrospective Cohort StudyArticle Published on 2022-10-252022-11-16 Journal: Journal of the Pediatric Infectious Diseases Socie [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI age Alpha analyses children clinical Community concern coronavirus 2 COVID-19 COVID-19 infection COVID-19 severity diagnosed with COVID-19 FIVE Frequency Gamma Hospitalization ICU admission illness Illumina immunization incidence increasing age marker medical condition Medical conditions outcome outcomes performed pharmacologic treatment prevented recent Regression model respiratory Respiratory Support retrospective cohort study SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 variant scale Sequencing severe COVID-19 severe disease severity Severity. single-center the WHO VoC VOCs were infected with COVID-19 [DOI] 10.1093/jpids/piac068 PMC 바로가기