retroviral – Communicable Diseases Research

Molecular diversity and phenotypic pleiotropy of ancient genomic regulatory loci derived from human endogenous retrovirus type H (HERVH) promoter LTR7 and HERVK promoter LTR5_Hs and their contemporary impacts on pathophysiology of Modern Humans

Article

Published on 2022-11-012022-11-15
Journal: Molecular genetics and genomics : MGG [Category] SARS, 유전자 메커니즘, 진단,

Limited cross-species transmission and absence of mutations associated with SARS-CoV-2 adaptation in cats: A case study of infection in a small household setting

고양이의 SARS-CoV-2 적응과 관련된 제한된 종간 전파 및 돌연변이 부재: 소규모 가정 환경에서의 감염 사례 연구

Article

Published on 2022-05-012022-09-11
Journal: Transboundary and emerging diseases [Category] COVID19(2023년), SARS, 변종, 치료기술,

[키워드] absence adaptation adaptive Anosmia Asymptomatic cat cats chain Clinical signs close contact collected Concentration concentrations Course COVID-19 Cross-species transmission Diagnosis Epidemiology fatigue flat highlight Human human SARS-CoV-2 strain human SARS-CoV-2 strains immunosuppressive Infection infections initial Interaction investigated Limited loss of taste Mutation naïve natural infection retroviral RT-PCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 strains SARS-CoV-2 transmission Seroconversion Serological testing sneezing Support Swab symptom onset Taste titre Transmission Viral RNA virus virus titre virus transmission were measured whole-genome sequencing
[DOI] 10.1111/tbed.14132 PMC 바로가기 [Article Type] Article

Syncytin, envelope protein of human endogenous retrovirus (HERV): no longer ‘fossil’ in human genome

Review

Published on 2022-01-122022-10-28
Journal: Animal Cells and Systems [Category] COVID-19,

Kinetics of SARS-CoV-2-Neutralising Antibodies of Residents of Long-Term Care Facilities

장기요양시설 입소자의 SARS-CoV-2-중화항체 동역학

Article

Published on 2022-01-012022-09-12
Journal: The journal of nutrition, health & aging [Category] SARS, 진단,

[키워드] affected Analysis Antibody titer appear BNT162b2 Care Cellular immune response COVID-19 elderly Epidemic evaluate facility Follow-up high risk Immunity immunosenescence Kinetics material median morbidity Mortality NAb titer NAbs neutralization test neutralizing antibody nine nursing homes outbreak participant Particle Patient patients Pfizer positive serology Quantitative remained resident retroviral S glycoprotein SARS-CoV-2 SARS-COV-2 infection Seroconversion serological Serological assay Serological testing seronegative shown significant difference statistically significant susceptible T cell the SARS-CoV-2 virus timepoint university vaccination Vaccination strategy Vaccine
[DOI] 10.1007/s12603-021-1713-4 PMC 바로가기 [Article Type] Article

Integration of SARS-CoV-2 RNA in infected human cells by retrotransposons: an unlikely hypothesis and old viral relationships

Commentary

Published on 2021-10-292022-10-29
Journal: Retrovirology [Category] COVID-19, MERS, SARS,

[키워드] available data Chimeric RNA COVID19 DNA elements explain HERV HERV-W human cell Hypothesis integration L1 LINE Patient persistence reported Retrotransposition retroviral SARS-CoV-2 SARS-CoV-2 infected patients SARS-CoV-2 RNA Topic unlikely viral sequence virus virus replication
[DOI] 10.1186/s12977-021-00578-w PMC 바로가기 [Article Type] Commentary

Upregulation of Human Endogenous Retroviruses in Bronchoalveolar Lavage Fluid of COVID-19 Patients

COVID-19 환자의 기관지폐포 세척액에서 인간 내인성 레트로바이러스의 상향 조절

Research Article

Published on 2021-10-062022-09-10
Journal: Microbiology Spectrum [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, 치료제,

[키워드] activated addition age analyzed BALF bronchial cell bronchial cells bronchial epithelial cell Bronchoalveolar lavage fluid Cancer cellular senescence changes in characterized China conditions controls Course COVID-19 COVID-19 patient COVID-19 patients COVID-19 pneumonia COVID-19 severity Disease progression disease severity dysregulated dysregulation element endogenous endogenous retroviruses epithelial cells examined explain exploration expression Families global pandemic groups HBEC HBECs healthy control healthy controls HERV HERVs Human human bronchial epithelial cells human endogenous retrovirus human endogenous retroviruses identify immune senescence increase in increasing age Infection Inflammation Inflammatory inflammatory pathway Inflammatory response Inflammatory responses Intensive lavage Local lung Lungs mechanism monocyte Monocytes Mortality Older age oncogene outcomes pathophysiological Patient PBMC PBMCs Peripheral blood peripheral blood monocytes Pneumonia populations Potential biomarker potential biomarkers potential therapeutic target provide recognize retroviral retrovirus risk factor SARS-CoV-2 senescent severe COVID-19 Severe COVID-19 pneumonia shown Transcriptome transcriptomes upregulated upregulation
[DOI] 10.1128/Spectrum.01260-21 PMC 바로가기 [Article Type] Research Article

Covid-19 pandemic: Perspectives on management

코로나19 팬데믹: 경영에 대한 관점

Review

Published on 2021-08-012022-09-11
Journal: Journal of reproductive immunology [Category] SARS, 임상, 치료제,

[키워드] ACE ACE inhibitors angiotensin Angiotensin receptor blockers assisted ventilation benefit Care clinical trials country COVAX COVID-19 COVID-19 vaccines decrease develop Dexamethasone dissemination distribution drug effective effective drug effective drugs effective therapy Efficacy Evidence evidence of form hypoxia ICU care identify in vitro activity Infection low dose dexamethasone management medical treatment Mild mRNA-based vaccine pandemic Patient Pneumonia preliminary evidence preventing infection progression provided randomized trial randomized trials receptor refrigeration Regulatory Remdesivir required retroviral SARS-CoV-2 severe disease shown supportive care the WHO Treatment vaccination Vaccine Vaccines virus
[DOI] 10.1016/j.jri.2021.103344 PMC 바로가기 [Article Type] Review

Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences

Echinacea purpurea (L.) 단핵구의 Moench 처리는 강장제 인터페론 신호 전달, 선천 면역 유전자 발현 증가 및 내인성 레트로 바이러스 서열의 DNA 반복 과메틸화 침묵을 촉진합니다

Research Article

Published on 2021-05-122022-09-10
Journal: BMC Complementary Medicine and Therapies [Category] SARS, 유전자 메커니즘, 치료제,

[키워드] Activation Analysis Antiviral change changes in characterisation chemokine chemotaxis common cold conserved CoV CpG Defense DNA DNA methylation Duration of infection Echinacea element epigenome experiment expression filgotinib Gene Expression genomic Herbal HERV HERVs IFN IFN signaling immunomodulation immunomodulatory effect induce inhibitor innate immune Innate immunity interferon interferon signaling involved janus Janus kinase kinase LTR monocyte Monocytes nuclear DNA Pathways Pattern recognition Pattern recognition receptors pharmacological promise promote Protective reduce Regulation respiratory Respiratory tract infections Result retroviral SARS-CoV-2 sequence Severe acute respiratory syndrome Signaling strain supplementary material Symptom Systems biology THP1 monocytes Transcription Transcriptome Treatment Trigger triggers Viral viral infections virus viruses
[DOI] 10.1186/s12906-021-03310-5 PMC 바로가기 [Article Type] Research Article

Intercellular viral spread and intracellular transposition of Drosophila gypsy

초파리 집시의 세포간 바이러스 전파 및 세포내 전위

Research Article

Published on 2021-04-222022-09-06
Journal: PLoS Genetics [Category] Communicable Disease,

[키워드] absence acquisition age aging ancestor animals arthropods assembly Author biological processe biological processes Cancer Cell chromosome chromosomes Combination develop disease Drosophila dysfunction element elements envelope gene Evidence exhibit exogenous retrovirus exogenous retroviruses expressed expression feature functional Genome genomes genomic germ line glial cell glial cells host genome implicated Implications incompatible increasingly infectious intercellular Like Long Long Terminal Repeat murine myriad neurodegeneration Neuron neurons occur organism plant plants Protein question raise related diseases Repeat replicate Replication retrotransposon retrotransposons retroviral retrovirus retroviruses similarity somatic cell somatic cells terminal the cell thought tissue transitioned Transmission Viral viral envelope protein viral spread Viral transmission viruses
[DOI] 10.1371/journal.pgen.1009535 PMC 바로가기 [Article Type] Research Article

Exaptation of Retroviral Syncytin for Development of Syncytialized Placenta, Its Limited Homology to the SARS-CoV-2 Spike Protein and Arguments against Disturbing Narrative in the Context of COVID-19 Vaccination

Review

Published on 2021-03-192022-10-28
Journal: Biology [Category] COVID-19,