A Multicenter Clinical Diagnostic Accuracy Study of SureStatus, an Affordable, WHO Emergency Use-Listed, Rapid, Point-Of-Care Antigen-Detecting Diagnostic Test for SARS-CoV-2Article Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 95% confidence interval access Accuracy acute respiratory syndrome Ag-RDT Ag-RDTs Analysis Antigen-detecting rapid diagnostic tests B.1.1.7 characterized circulating clinical Combination complement coronavirus COVID-19 Critical cycle threshold demonstrated diagnostic Emergency Emergency use evaluated facilitate Factor Germany gold standard highlight independent India multicenter nasopharyngeal Oropharyngeal overcome participant Participants performance performed point-of-care positive post-symptom onset questionnaire raised Rapid Rapid diagnostic test recruited resources reverse transcription-PCR RT-PCR RT-PCR testing SARS-CoV-2 SARS-COV-2 infection sensitivity specificity specificity. subgroup subgroups Support SUS Swab symptom duration symptom onset Symptoms Test Transmission variant Viral load was used WHO widespread World Health Organization [DOI] 10.1128/spectrum.01229-22 PMC 바로가기
Comparison of SARS-CoV-2 Detection from Saliva Sampling and Oropharyngeal SwabArticle Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95% CI 95% confidence interval acute respiratory syndrome addition analyzed buffer Care clinics Cohort collected Community comparable coronavirus COVID-19 COVID-19 pandemic detection detection rate effective ENhance examined feasible flexible Health Large-scale testing lockdowns Oropharyngeal oropharyngeal swab pandemic performed positive reduce resource reverse transcription-PCR RNA RNA stability RT-PCR RT-qPCR Saliva Saliva. sampling SARS-CoV-2 SARS-CoV-2 detection Schools screening method sensitivity Sensitivity and specificity specificity stability subject subjects Swab swabbing symptomatic and asymptomatic temperature Viral RNA was used [DOI] 10.1128/spectrum.01422-22 PMC 바로가기
Comparison of the SARS-CoV-2 BD Veritor Nasal Antigen Test with Nasopharyngeal Reverse Transcription-PCR in Symptomatic PatientsArticle Published on 2022-10-262022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, [키워드] Accuracy addition analyzed Antigen asymptomatic patient coronavirus COVID-19 cycle threshold Diagnosis diagnostic evaluated genes encoding immunochromatographic Infection information Interpretation methodology nasopharyngeal oropharyngeal swab Patient performed POC POC test point-of-care point-of-care test point-of-care testing provide rapid antigen test Rapid test rapid tests. reduce reproducibility reverse transcription-PCR RT-PCR Safe saline solution Sample SARS-CoV-2 sensitivity symptom onset symptomatic Symptomatic patients temperature Test tested the SARS-CoV-2 Variation Veritor test [DOI] 10.1128/spectrum.00190-22 PMC 바로가기
Cross-sectional study for COVID-19-related mortality predictors in a Brazilian state-wide landscape: the role of demographic factors, symptoms and comorbiditiesArticle Published on 2022-10-172022-11-15 Journal: BMJ Open [Category] 진단, [키워드] 95% CI Analysis association cardiac epidemiology Clinical severity Comorbidity COVID-19 COVID-19 pandemic criteria criterion cross-sectional study dataset death demographic characteristics Demographic factors diabete diabetes & diagnosed disease disorder Effects electronic medical record endocrinology Epidemiology evaluate Factor health system healthcare highlight hospitalisation hospitalised ICU implementation increased mortality information Intervention kidney kidney & Kidney disease majority measure mitigate Mortality multicollinearity non-hospitalised non-ICU non-ICU patient occurred Patient patients patients older predictor Prevent public health public health. reverse transcription-PCR secondary outcome selected severity Sex state suffered Symptom Urinary tract urinary tract disorders virus [DOI] 10.1136/bmjopen-2021-056801 PMC 바로가기
Immunomolecular assay based on selective virion capture by spike antibody and viral nucleic acid amplification for detecting intact SARS-CoV-2 particlesArticle Published on 2022-09-052022-11-15 Journal: Journal of Nanobiotechnology [Category] SARS, 치료기술, [키워드] Accuracy acute respiratory syndrome aluminum amplification analyses antibody applied Characteristics clinical sample coefficient Complete Complete virions conditions convalescent coronavirus coronavirus disease COVID-19 Critical detect diagnose facilitate Factor glycoprotein Human immunodeficiency virus human serum Immune escape Immunomolecular detection IMPROVE infection risk Influenza isolation rooms limit of detection molecular monoclonal antibody Mutation nucleic acid amplification Outbreaks parameters Patient pseudovirus quantified Quantitative reduced reverse transcription PCR reverse transcription-PCR SARS-CoV-2 SARS-CoV-2 particle SARS-CoV-2 pseudovirus selective specific antibodies spike Spike. stability Vaccine Variation Viral load viral nucleic acid viral spike viral titer virion virions virus virus detection virus isolation viruses [DOI] 10.1186/s12951-022-01558-8 PMC 바로가기
Efficacy of single-dose and double-dose ivermectin early treatment in preventing progression to hospitalization in mild COVID-19: A multi-arm, parallel-group randomized, double-blind, placebo-controlled trial경증 COVID-19에서 입원으로의 진행을 예방하는 단일 용량 및 이중 용량 이버멕틴 조기 치료의 효능: 다군, 병렬 그룹, 무작위, 이중 맹검, 위약 대조 시험Randomized Controlled Trial Published on 2022-09-012022-09-11 Journal: Respirology (Carlton, Vic.) [Category] COVID19(2023년), SARS, 임상, 치료제, [키워드] absolute difference adverse event anti-parasitic Antiviral antiviral agent Clinical course clinical trial conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection dermatitis double-blind early treatment Efficacy enrolled evaluate Hospitalization hypertension investigated Ivermectin ivermectin group Mild mild COVID-19 mild COVID-19 patients Mild symptom mild symptoms multi-arm no significant difference parallel-group Patient Placebo placebo group placebo-controlled trial Primary outcome progression proportion proportions Randomized randomized clinical trial randomized clinical trial. receive required reverse transcription reverse transcription-PCR SARS-CoV-2 severity Severity Score Single-dose statistically significant subject Tachycardia [DOI] 10.1111/resp.14318 PMC 바로가기 [Article Type] Randomized Controlled Trial
High-Throughput COVID-19 Testing of Naso-Oropharyngeal Swabs Using a Sensitive Extraction-Free Sample Preparation MethodArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] SARS, 치료기술, [키워드] approach calibrated Cobas costly COVID-19 detection system diagnosis of SARS-CoV-2 diagnostic Direct direct method downstream extraction-free extraction-free method gold standard high-throughput. Infection International lack less log medium naso-oropharyngeal swab nasopharyngeal swab specimen nucleic acid extraction offer ORF1ab outcome PCR PCR assay per day PlexPCR pool positive sample preparation proteinase protocol purification quantification RdRP reagent reagents reduction in required Respiratory Coronavirus reverse transcription-PCR RNA Roche Sample SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA sensitive sensitivity tested Testing time-consuming Transport Treatment Viral load Viral RNA WHO [DOI] 10.1128/spectrum.01358-22 PMC 바로가기
Limitations of Molecular and Antigen Test Performance for SARS-CoV-2 in Symptomatic and Asymptomatic COVID-19 Contacts증상 및 무증상 COVID-19 접촉자에서 SARS-CoV-2에 대한 분자 및 항원 테스트 성능의 한계Article Published on 2022-07-202022-09-12 Journal: Journal of Clinical Microbiology [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] acute respiratory syndrome Antigen antigen test Asymptomatic individuals Cell culture close contact Contact coronavirus COVID-19 Culture diagnostics enrolled identify in viral individual Infection limitation Molecular assay nasopharyngeal NAT nucleic acid test pandemic participant performance performed PerkinElmer platform positive positive sample Probability rapid diagnostics recruited reference Repeat reverse transcription-PCR RT-PCR RT-PCR assay Saliva SARS-CoV-2 SARS-CoV-2 testing SARS-CoV-2-positive individual Swab Symptom symptomatic Test test performance. tested Transport media VTM [DOI] 10.1128/jcm.00187-22 PMC 바로가기 [Article Type] Article
Evaluation of the Panbio COVID-19 Antigen Rapid Diagnostic Test in Subjects Infected with Omicron Using Different Specimens다양한 표본을 사용하여 오미크론에 감염된 피험자에서 Panbio COVID-19 항원 신속 진단 검사 평가Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Ag-RDT amplification Antigen B.1.1.529 Concordance coronavirus COVID-19 COVID-19 diagnosis COVID19 demonstrated Diagnosis diagnostic test Infection mutated nasal nasal swab nasal swabs nasopharyngeal sample Nasopharyngeal samples omicron Omicron variant oral oral swab oral swabs PanBio pandemic Patient PCR positive sample primary site Quantitative quantitative reverse transcription-PCR raised Rapid Rapid antigen tests Rapid diagnostic test Rapid test rapid test. Replication reverse transcription-PCR RT-qPCR sample collection SARS-CoV-2 SARS-CoV-2 positivity sensitivity severe acute respiratory syndrome Coronavirus specimen symptomatic individuals Test tested Transmission variant VoC was performed was used [DOI] 10.1128/spectrum.01250-22 PMC 바로가기 [Article Type] Article
Risk of COVID-19 re-infection and its predictors (CORES): protocol for a community-based longitudinal cohort study in Vellore, IndiaCOVID-19 재감염 및 그 예측인자(CORES)의 위험: 인도 벨로르에서 지역사회 기반 종단 코호트 연구를 위한 프로토콜Article Published on 2022-05-242022-09-11 Journal: BMJ Open [Category] COVID19(2023년), SARS, 치료기술, [키워드] analysed antibody Antibody responses approved attack rate B cell memory baseline blood sample Blood samples collected college Community community setting COVID-19 defined detect elicited Ethics evaluated Evidence evidence of expected Factor General population group Health policy healthy immune response immune responses immunology incidence India Infection institutional review board IRB Kinetics Longevity longitudinal cohort study natural infection positive Post-infection predictor presence of antibody Primary infection protocol public health public health. Re-infection recruit registration number registry responses reverse transcription-PCR risk risk factor Risk factors RT-PCR Saliva saliva samples SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 infections SARS-CoV-2 spike protein seronegative seropositive Seropositivity Seroprevalence seroprevalence survey Spike protein T cell T cell memory tested understanding vaccination Vaccination Status Weekly [DOI] 10.1136/bmjopen-2021-059869 PMC 바로가기 [Article Type] Article