Clonal hematopoiesis of indeterminate potential and risk of death from COVID-19Article Published on 2022-11-032022-11-16 Journal: Blood [Category] Fulltext, MERS, 변종, [키워드] COVID-19 Hematopoiesis risk of death [DOI] 10.1182/blood.2022018052 PMC 바로가기
Sex differences in determinants of COVID-19 severe outcomes – findings from the National COVID Cohort Collaborative (N3C)Article Published on 2022-10-122022-11-15 Journal: BMC Infectious Diseases [Category] 바이오마커, [키워드] absolute lymphocyte absolute neutrophil adjusted adjusted odds ratio Admission age Analysis association averaged Biomarker Biomarkers both sexes CCI Charlson Comorbidity Index comorbid condition Comorbidities Comorbidity components COVID COVID-19 COVID-19 severity CRP death death rate defined determinant disease Elevation examined ferritin Health highlight hospital Hospitalized IMV Inflammation inflammatory biomarkers Invasive mechanical ventilation lab value Liver disease Logistic regression LOS lymphocytopenia magnitude male medication men men and women moderate to severe Mortality Myocardial infarction N-terminal neutrophil outcome Patient peptide Platelet Platelets predictor previous study Primary outcome procalcitonin Protein remained renal Research retrospective cohort risk risk factor risk of death secondary outcome Sex Sex difference sex differences significantly solid tumor with COVID-19 women [DOI] 10.1186/s12879-022-07776-7 PMC 바로가기
Application of a Decision Tree Model to Predict the Outcome of Non-Intensive Inpatients Hospitalized for COVID-19Article Published on 2022-10-112022-11-15 Journal: International Journal of Environmental Research an [Category] 진단, [키워드] Accuracy application applied approach Blood clinical aspect clinician coronavirus disease COVID-19 decision Disease progression evaluate haematochemical parameters Health help Immunoglobulin information Inpatient intensive care units International machine learning Model normalized outcome outcomes parameter Patient patients with COVID-19 physician prediction predictor Prognostic markers Prospective Study Prothrombin time repeated Research Retrospective study risk of death sensitivity specificity threshold to define tree worsening [DOI] 10.3390/ijerph192013016 PMC 바로가기
Coronavirus Disease 2019 (COVID-19) Severity Among Women of Reproductive Age With Symptomatic Laboratory-Confirmed Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection by Pregnancy Status-United States, 1 January 2020-25 December 2021Article Published on 2022-10-032022-11-16 Journal: Clinical Infectious Diseases: An Official Publicat [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI acute respiratory syndrome adjusted Admission age aRR calculated confidence interval coronavirus coronavirus 2 coronavirus disease COVID-19 death Delta delta variant ECMO extracorporeal membrane oxygenation ICU ICU admission increased risk Infection intensive care invasive ventilation nonpregnant Pregnancy pregnant reproductive respiratory risk risk of death risk ratio SARS-CoV-2 severe COVID-19 severe disease severity symptomatic the United State were assessed women women of reproductive age. [DOI] 10.1093/cid/ciac479 PMC 바로가기
Association Between Maintenance Immunosuppressive Regimens and COVID-19 Mortality in Kidney Transplant RecipientsArticle Published on 2022-10-012022-11-15 Journal: Transplantation [Category] 진단, [키워드] age association baseline baseline characteristics cardiovascular disease cohort study Comorbidity conducted coronavirus disease Corticosteroid COVID-19 death diabete died evaluated False positive form French high risk hypertension immune function Immunosuppression immunosuppressive immunosuppressive drug impair inhibitor kidney transplant Logistic regression lower risk maintenance mammalian men Mortality MOST multiple imputation Odds ratio outcome p value performed Rapamycin recipient recipients regimen registry retrieved risk of death serum creatinine significantly lower Solid solid organ solid organ transplant statistically significant Transplant was used with COVID-19 [DOI] 10.1097/TP.0000000000004254 PMC 바로가기
IGHG3 hinge length variation was associated with the risk of critical disease and death in a Spanish COVID-19 cohortArticle Published on 2022-09-012022-11-15 Journal: Genes and Immunity [Category] SARS, 진단, [키워드] 95% CI adverse effect Affect allele Amino acid carrier cohorts COVID-19 COVID-19 cohort Critical Critical disease death explained functions genotyped ICU IgG3 IGHG3 immune adaptive response impair increased risk induce less moderate-severe Mortality neutralization Patient phagocytosis plasma polymorphism reduce reduced risk risk of COVID-19 risk of death S allele SARS-CoV-2 sequence severity Spanish Variation viral neutralization [DOI] 10.1038/s41435-022-00179-3 PMC 바로가기
Impact of diabetes on COVID-19 prognosis beyond comorbidity burden: the CORONADO initiativeClinical Trial Published on 2022-09-012022-10-05 Journal: Diabetologia [Category] COVID19(2023년), SARS, 임상, [키워드] 1:1 adjusted Admission advanced age age Analysis Aspartate aminotransferase BMI C-reactive protein Charlson index Clinical outcome cohort study Comorbidities Comorbidity component coronavirus disease COVID-19 COVID-19 prognosis COVID-19 symptom death Deleterious diabete diabetes disease Dyspnoea French higher risk hospital Hospital admission Impact IMV individual Invasive mechanical ventilation multivariable analysis occurred participant Patient performed Platelet primary composite endpoint primary endpoint Prognosis Prognostic factor question remained risk risk factor risk of death SARS-CoV-2 Sex variable white cell with COVID-19 women [DOI] 10.1007/s00125-022-05734-1 PMC 바로가기 [Article Type] Clinical Trial
Age-Specific Changes in Virulence Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variants of Concern중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 변종 우려와 관련된 병독성의 연령별 변화Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 치료기술, [키워드] 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted Admission age all age groups association Canada change children Comorbidity concern coronavirus coronavirus 2 death Delta VOC delta VoCs Elevation Epidemiology estimate evaluate Factor greater group Health health outcomes Hospitalization ICU ICU admission increase in increases in individual individuals Infection intensive care intensive care unit logistic regression model Model novel Older outcome positive respiratory retrospective cohort risk risk of death SARS Coronavirus SARS coronavirus-2 SARS-CoV-2 screened severe acute respiratory syndrome Coronavirus severity Sex tested vaccination Vaccination Status variables variants of concern virulence VoC VOCs [DOI] 10.1093/cid/ciac174 PMC 바로가기 [Article Type] Article
Timing and Outcomes of Noninvasive Ventilation in 307 ARDS COVID-19 Patients: An Observational Study in an Italian Third Level COVID-19 HospitalObservational Study Published on 2022-08-152022-10-05 Journal: Medicina [Category] 임상, [키워드] 95% CI acute respiratory distress acute respiratory distress syndrome adjusted odds ratio analyzed appear ARDS ARDS COVID-19 patient conducted Coronavirus disease 2019 correlated COVID-19 COVID-19 pandemic COVID-19 patient death defined Effectiveness Efficacy etiologies Evidence Factor hospital Hospital wards Hospitalization ICU ICU admission increased risk independent intensive care intensive care unit intubated COVID-19 patient intubation Italian Italy lack Level Logistic regression analysis lower mortality material Mild moderate Mortality NIV NIV failure noninvasive Noninvasive ventilation objective Observational cohort study occurred Occurrence orotracheal intubation. outcome P/F Patient patients patients with ARDS patients with COVID-19 reduce respiratory Result risk risk of death Rome severe ARDS severity significantly study period Support treated Treatment Ventilation [DOI] 10.3390/medicina58081104 PMC 바로가기 [Article Type] Observational Study
Effect of interleukin-6 receptor antagonists in critically ill adult patients with COVID-19 pneumonia: two randomised controlled trials of the CORIMUNO-19 Collaborative GroupCOVID-19 폐렴이 있는 위독한 성인 환자에서 인터루킨-6 수용체 길항제의 효과: CORIMUNO-19 공동 그룹의 2건의 무작위 대조 시험Article Published on 2022-08-102022-09-11 Journal: The European Respiratory Journal [Category] Fulltext, SARS, 임상, [키워드] 95% CI antagonist anti-IL-6 receptor assigned Bayesian clinical trials clinically controlled clinical trials coronavirus disease Coronavirus disease 2019 COVID-19 credible interval CrI Critically ill Critically ill patient critically ill patients determine Effect events group hazard ratio IMPROVE indicated interleukin-6 receptor intravenously investigator-initiated mechanical ventilation median multicentre NIV Noninvasive ventilation not need numbers of patient Open-label outcome Patient patients with COVID-19 Pneumonia posterior probability randomised randomised controlled randomised controlled trial Randomly receive receptor risk of death SARI sarilumab significantly TCZ TOCI Tocilizumab Trial usual care with COVID-19 [DOI] 10.1183/13993003.02523-2021 PMC 바로가기 [Article Type] Article