Expression of virus-like particles (VLPs) of foot-and-mouth disease virus (FMDV) using Saccharomyces cerevisiaeApplied Genetics and Molecular Biotechnology Published on 2024-01-092024-09-05 Journal: Applied Microbiology and Biotechnology [Category] update2024, [키워드] Capsid protein FMDV Ribosomal skipping Saccharomyces cerevisiae Virus-like particle [DOI] 10.1007/s00253-023-12902-9 PMC 바로가기 [Article Type] Applied Genetics and Molecular Biotechnology
The Saccharomyces cerevisiae Spo7 basic tail is required for Nem1–Spo7/Pah1 phosphatase cascade function in lipid synthesisResearch Article Published on 2023-12-212024-09-05 Journal: Brain stimulation [Category] update2024, [키워드] diacylglycerol lipid droplet membrane Nem1 Pah1 phosphatidate phosphatase phospholipid Protein phosphatase Saccharomyces cerevisiae Spo7 triacylglycerol yeast [DOI] 10.1016/j.jbc.2023.105587 PMC 바로가기 [Article Type] Research Article
Evaluation of a Functional Craft Wheat Beer Fermented with Saccharomyces cerevisiae UFMG A-905 to treat Salmonella Typhimurium infection in micearticle Published on 2023-10-312024-09-01 Journal: Probiotics and Antimicrobial Proteins [Category] 살모넬라증, [키워드] Functional foods Probiotic Saccharomyces cerevisiae Salmonella Typhimurium Wheat beer [Article Type] article
Hemagglutinin expressed by yeast reshapes immune microenvironment and gut microbiota to trigger diverse anti-infection response in infected birdsArticle Published on 2023-04-182023-06-14 Journal: Frontiers in Immunology [Category] Fulltext, 조류인플루엔자, [키워드] H5N8 Hemagglutinin (HA) influenza A virus Saccharomyces cerevisiae Vaccine [DOI] 10.3389/fimmu.2023.1125190 PMC 바로가기
Steric accessibility of the N-terminus improves the titer and quality of recombinant proteins secreted from Komagataella phaffiiArticle Published on 2022-09-052022-11-16 Journal: Microbial Cell Factories [Category] SARS, 변종, [키워드] addition addressed aggregation Alpha Amino acid applied benefit caused Cell cleavage cleave demonstrated eliminated extension extracellular space functional Golgi highest Host IMPROVE Modification N-terminal N-terminus observation occur peptide Pichia Pichia pastoris product Product quality protease Protein protein engineering protein sequence Proteins purification Receptor binding domain Recombinant protein recombinant proteins residue Saccharomyces cerevisiae secrete secreted secreted protein secretion signal signal peptide steric steric hindrance subunit the SARS-CoV-2 the signal peptide therapeutic vaccine antigen variant variants [DOI] 10.1186/s12934-022-01905-2 PMC 바로가기
Display of receptor-binding domain of SARS-CoV-2 Spike protein variants on the Saccharomyces cerevisiae cell surfaceArticle Published on 2022-08-122022-11-15 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, [키워드] ACE2 acute respiratory syndrome Antibody neutralization antiserum approach B.1.1.7 B.1.351 B.1.617.1 B.1.671.1 Beta binding candidate Cell cellular immune responses coronavirus disease Coronavirus-2 COVID-19 Culture display domain effective enzyme escaped Express Health humoral inducer initial knocked out mutant Neutralizing activity pandemic Protein RBD RBD binding RBDs Receptor-binding domain reduction robust Saccharomyces cerevisiae SARS-CoV-2 SARS-CoV-2 vaccine spike the receptor-binding domain vaccination Vaccine vaccine candidate variant variants wild-type yeast yeast surface display. [DOI] 10.3389/fimmu.2022.935573 PMC 바로가기
Complex Portal 2022: new curation frontiersAcademicSubjects/SCI00010 Published on 2022-01-072022-10-31 Journal: Nucleic Acids Research [Category] Coronavirus, [키워드] added Analysis cofactor Community collaboration complex complexes contributing to coronavirus curated database draft Escherichia coli example feature immune system include macromolecular Organisms portal produced Protein resource reuse Saccharomyces cerevisiae target Topology Transcription user Viral protein Wikidata [DOI] 10.1093/nar/gkab991 PMC 바로가기 [Article Type] AcademicSubjects/SCI00010
Effect and Tolerability of a Nutritional Supplement Based on a Synergistic Combination of β-Glucans and Selenium- and Zinc-Enriched Saccharomyces cerevisiae (ABB C1 ® ) in Volunteers Receiving the Influenza or the COVID-19 Vaccine: A Randomized, Double-Blind, Placebo-Controlled StudyArticle Published on 2021-12-022022-10-31 Journal: Nutrients [Category] COVID-19, [키워드] β-1,3/1,6-glucan complex baseline CD8+T lymphocyte Cell change Combination complex conducted COVID-19 COVID-19 cohort COVID-19 vaccine decrease double-blind Effect groups IgG and IgM Immunity increase in increases in Influenza influenza vaccine ingredient nutritional supplementation Placebo placebo-controlled study Randomized reported Saccharomyces cerevisiae second dose Selenium Serious Adverse Event single-center stimulate subject synergistic the placebo group those receiving placebo Tolerance trained immunity treated Treatment unique Volunteer Zinc [DOI] 10.3390/nu13124347 PMC 바로가기 [Article Type] Article
A Genetic Trap in Yeast for Inhibitors of SARS-CoV-2 Main ProteaseMethods and Protocols Published on 2021-11-232022-10-29 Journal: mSystems [Category] COVID-19, [키워드] absence Antiviral antiviral agent Antiviral agents antiviral drug blocked candidate Cell cells cellular cleavage cleavage site Compound COVID-19 COVID-19 pandemic detect drug candidate drug target effective ENhance Escherichia coli fluorescent genetic engineering genetic selection system growth IMPROVE in vivo Infection inhibited inhibiting inhibitor inhibitors insertion linker live cell marker MazF toxin Modification mutant other proteases peptide platform Positive selection protease Protease inhibitor Protein required resulting robust Saccharomyces cerevisiae SARS-CoV-2 small molecule small molecule inhibitor Small molecules Specificities Symptoms the SARS-CoV-2 vaccination variant viral replication yeast yeast cell yeast cells [DOI] 10.1128/mSystems.01087-21 PMC 바로가기 [Article Type] Methods and Protocols
Construction of Non-infectious SARS-CoV-2 Replicons and Their Application in Drug Evaluation비감염성 SARS-CoV-2 레플리콘의 구축 및 약물 평가에서의 적용Article Published on 2021-10-012022-09-11 Journal: Virologica Sinica [Category] SARS, 신약개발, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus antiviral drug antiviral drugs application biosafety level Biosafety Level 3 biosafety level 3 laboratory candidate caused Cell combating construction coronavirus drug Drug evaluation E64-D effort Epidemic experiment expression firefly luciferase fluorescent Genes genetics half-maximal effective concentration inhibitory effect Inhibitory effects Laboratory level 3 manipulation non-infectious pandemic performed Plasmid Protein Quantification method Recombination Remdesivir Replication replicon reporter reverse genetics Saccharomyces cerevisiae SARS-CoV-2 SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 the SARS-CoV-2 time-consuming virus [DOI] 10.1007/s12250-021-00369-9 PMC 바로가기 [Article Type] Article