Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases조직간 단세포 기질 아틀라스는 4가지 만성 염증성 질환에서 공유된 병리학적 섬유아세포 표현형을 식별합니다.Article Published on 2022-07-082022-09-11 Journal: Med (New York, N.Y.) [Category] 비임상, [키워드] Activation affected animal model animal models Arthritis atlas atopic dermatitis breath CCL19 chronic inflammatory disease chronic inflammatory diseases Clusters COL3A1 Critical CXCL10 disease Diseases donors exacerbated fibroblast fibroblasts Foundational research heterogeneity Hoffmann-La Roche identify immune individual inflamed tissue Inflammation Inflammatory bowel disease Inflammatory diseases integration interstitial Interstitial lung disease intestinal inflammation intestine joint lack lung Lung disease Lungs mapped organ systems Pathogenesis pathogenic pathway Pathways phenotype Phenotypes pro-inflammatory reveal rheumatoid arthritis Roche salivary gland salivary glands scRNA-seq single-cell Single-cell RNA sequencing Sjögren's syndrome SPARC stromal syndrome synovium therapeutic target ulcerative colitis [DOI] 10.1016/j.medj.2022.05.002 PMC 바로가기 [Article Type] Article
Oral mucosa lesions in confirmed and non-vaccinated cases for COVID-19: A systematic reviewMini review Published on 2022-05-012022-10-05 Journal: Journal of stomatology, oral and maxillofacial sur [Category] 바이오마커, 진단, [키워드] acute phase age association Care Clinical characteristics conducted confirmed cases coronavirus correlation COVID-19 COVID-19 patient COVID-19 severity database described eligible endothelial cells Health histological identify Inflammatory lesion Mild moderate mucosa oral oral cavity Oral lesion oral mucosa Patient professional salivary glands Seven severity Sex Symptom Symptoms systematic review thrombosis tongue Treatment vacuolization virus [DOI] 10.1016/j.jormas.2022.05.005 [Article Type] Mini review
Salivary and Intestinal Transcriptomes Reveal Differential Gene Expression in Starving, Fed and Trypanosoma cruzi -Infected Rhodnius neglectusOriginal Research Published on 2021-12-172023-08-30 Journal: Frontiers in Cellular and Infection Microbiology [Category] E형 간염, [키워드] intestine salivary glands Transcriptome Triatomine Trypanosoma cruzi [DOI] 10.3389/fcimb.2021.773357 PMC 바로가기 [Article Type] Original Research
Multisystemic Cellular Tropism of SARS-CoV-2 in Autopsies of COVID-19 PatientsCOVID-19 환자의 부검에서 SARS-CoV-2의 다중 전신 세포 친화성Article Published on 2021-07-272022-09-11 Journal: Cells [Category] SARS, 치료기술, [키워드] ACE2 adrenal gland alteration analyzed assigned Autopsies Autopsy bowel Cell Chain Reaction correlation COVID-19 COVID-19 autopsy sample electron microscopy endothelial cells epithelial epithelial cell epithelial cells expressing fatal COVID-19 FFPE formalin formalin-fixed paraffin-embedded formalin-fixed paraffin-embedded (FFPE) tissue heart histology histopathological immunohistochemistry In situ hybridization Infection kidney liver lung lymph nodes major organs Microscopy organ systems organs oropharynx paraffin polymerase chain polymerase chain reaction Post-mortem Prostate Replication respiratory respiratory tract RNA salivary glands SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 RNA shown Skeletal muscle skin the SARS-CoV-2 Thyroid TMPRSS2 tonsils Trachea transmission electron microscopy tropism tropism of SARS-CoV-2 Viral Viral detection Viral protein Viral RNA virus particle virus particles [DOI] 10.3390/cells10081900 PMC 바로가기 [Article Type] Article
Exosomes mediate horizontal transmission of viral pathogens from insect vectors to plant phloemArticle Published on 2021-07-022023-08-30 Journal: eLife [Category] E형 간염, [키워드] Exosome insect vectors multivesicular bodies plant phloem salivary glands Viral transmission virus [DOI] 10.7554/eLife.64603 PMC 바로가기
Salivary glands are a target for SARS-CoV-2: a source for saliva contamination침샘은 SARS-CoV-2의 표적입니다: 타액 오염의 원인Article Published on 2021-07-012022-09-11 Journal: The Journal of pathology [Category] SARS, 치료기술, 치료법, 치료제, [키워드] ACE2 acinar cell age alteration Analysis analyzed anti-SARS-CoV-2 antibody Autopsy biopsy Cell cells change characterized Cluster conducted Contamination Coronaviridae family COVID-19 COVID-19 pandemic cytoplasm cytoplasmic degeneration degenerative determinant determinants Diagnostic method duct electron microscopy enlarged nuclei epithelial cell epithelial cells expression female Granule Great Britain highlight histopathological identify immunohistochemistry infected cell infected cells Infection infection control Ireland lining epithelium male Microscopy nasopharyngeal swabs New coronavirus new coronavirus SARS-CoV-2 nuclear nuclear pleomorphism nucleocapsids organelle pathological pathophysiological Patient patients positive profile Qualitative Quantitative receptors reservoir RT-PCR RT-PCR, SARS-CoV-2 RT-qPCR Saliva salivary salivary gland salivary gland. salivary glands Sample SARS-CoV-2 sensitivity shape Society Sons Spread tested the Coronaviridae the disease TMPRSS Ultrasound vacuolization Viral particles viral replication [DOI] 10.1002/path.5679 PMC 바로가기 [Article Type] Article
Presence of SARS-CoV-2 and Its Entry Factors in Oral Tissues and Cells: A Systematic Review구강 조직 및 세포에서 SARS-CoV-2의 존재 및 진입 요인: 체계적인 검토Review Published on 2021-05-232022-09-10 Journal: Medicina [Category] SARS, 치료기술, [키워드] ACE2 ACE2 expression acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed angiotensin Angiotensin-converting enzyme carried Cell cell layer cells Consequences coronavirus COVID-19 database entry factors epithelial epithelial cell epithelial cells expressed expression Factor furan furin horny layer inclusion criteria independent infect item material Meta-analysis myoepithelial cells objective oral oral cavity oral mucosa oral tissue oral tissues Other pandemic Presence PRISMA Protein provide reported Reporting researchers respiratory review salivary gland salivary glands SARS-CoV-2 SARS-CoV-2 positive patients Serine severe acute respiratory syndrome Coronavirus Symptom systematic review TMPRSS TMPRSS11D TMPRSS2 TMPRSS3 TMPRSS4 TMPRSS5 TMPRSS7 tongue transmembrane serine protease variety virus infection Web were used [DOI] 10.3390/medicina57060523 PMC 바로가기 [Article Type] Review
Oral manifestations of COVID ‐19 patients: An online survey of the Egyptian populationOriginal Article Published on 2021-05-012022-11-01 Journal: Clinical and Experimental Dental Research [Category] COVID-19, MERS, SARS, [키워드] age association Cairo Coronavirus disease 2019 COVID COVID‐19 COVID‐19 infection COVID‐19 patient COVID‐19 patients COVID‐19 demographic data diagnosed disorder dysfunction expected females Gender gingival bleeding Gustatory healthcare highest hospital Impact incidence male manifestation material objective oral health oral lesions oral manifestation Participants pilot study positive Prevalence prevalent questionnaire reported Result reverse transcriptase PCR RT‐PCR salivary salivary glands SARS‐CoV‐2 significantly sweet Symptom the patient tongue [DOI] 10.1002/cre2.429 PMC 바로가기 [Article Type] Original Article
Rare Diseases of the Salivary Glands and of Facial NerveReferateband Published on 2021-04-302024-09-04 Journal: Laryngo- rhino- otologie [Category] 대상포진, [키워드] Facial nerve facial palsy facial tumor Facialisparesen Facialistumoren Nervus Facialis salivary gland infection salivary gland tumor salivary glands Speicheldrüsen Speicheldrüsenentzündungen Speicheldrüsentumoren [DOI] 10.1055/a-1337-6994 PMC 바로가기 [Article Type] Referateband
Saliva: What Dental Practitioners Should Know about the Role of This Biofluid in the Transmission and Diagnostic of SARS-CoV-2타액: SARS-CoV-2의 전파 및 진단에서 이 생체액의 역할에 대해 치과의사가 알아야 할 사항Review Published on 2021-04-062022-09-10 Journal: Medicina [Category] MERS, SARS, 치료기술, [키워드] ACE2 receptor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected binding Cell cells Contact contact with Contagion contribute coronavirus cough COVID-19 dental dental practice dentist dentists develop Diagnosis diagnostic diagnostic methods epithelial cell epithelial cells Evidence evidence of expected explain Express furin Health host cells include infected patient infected patients Infection information knowledge means mechanism Nasopharyngeal swab offer oral health oral tissue oral tissues outbreak pandemic Perspective Practitioner professional professionals Protein provide respiratory risk role Saliva saliva samples salivary glands SARS-CoV-2 SARS-COV-2 infection scientific evidence sneeze Spread Support Surveillance susceptible the disease tissue tissues TMPRSS Transmission variety virus [DOI] 10.3390/medicina57040349 PMC 바로가기 [Article Type] Review