Exploring polyamine interactions and binding pockets in SARS-CoV-2 ORF3aArticle Published on 2023-04-102024-09-05 Journal: Journal of molecular graphics & modelling [Category] update2024, [키워드] molecular docking molecular dynamics ORF3a SAR-CoV-2 spermidine [DOI] 10.1016/j.jmgm.2023.108487 PMC 바로가기 [Article Type] Article
Electrochemical paper-based antigen sensing platform using plant-derived monoclonal antibody for detecting SARS-CoV-2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 진단, 치료기술, 치료제, [키워드] anti-SARS-CoV-2 antibody Antigen applicability applied approach Cellulose Concentration COVID-19 diagnosis CR3022 detect diagnostic Differential pulse voltammetry expressed functional group limit of detection linear relationship monoclonal antibody nasopharyngeal swab sample Nicotiana benthamiana Paper-based electrochemical immunosensor Plant-based antibody platform point-of-care pulse quantification RBD Receptor binding domain Saliva SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection Spike protein the RBD this system was performed [DOI] 10.1016/j.talanta.2022.123783 PMC 바로가기
Routine pre-operative Covid testing in elective surgeries: Is it worth it?Observational Study Published on 2022-12-012023-07-10 Journal: The American Journal of Surgery [Category] COVID19(2023년), [키워드] COVID-19 preoperative testing Preprocedural testing SAR-CoV-2 Screening [DOI] 10.1016/j.amjsurg.2022.10.035 PMC 바로가기 [Article Type] Observational Study
Whole-genome sequence analysis reveals the circulation of multiple SARS-CoV-2 variants of concern in Nairobi and neighboring counties, Kenya between March and July 2021Article Published on 2022-11-082022-11-16 Journal: Virology Journal [Category] SARS, 변종, [키워드] adaptive Analysis analyzed B.1.1.7 B.1.351 B.1.617.2 Beta bioinformatics circulation community transmission comparison Coronaviruses COVID-19 COVID-19 cases Delta Epidemics genome sequence increase in Kenya Lineage majority Mutation Neutralizing antibodies Oxford Nanopore Technologies Phylogenetic Prevalence protocol reduced Region regions reveal RNA RT-PCR SAR-CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 variant sequence Sequence analysis Sequencing Spread Strains study period the SARS-CoV-2 variant virulence virus virus transmissibility VoC was performed [DOI] 10.1186/s12985-022-01895-y PMC 바로가기
Seroprevalence, correlates and kinetics of SARS-CoV-2 nucleocapsid IgG antibody in healthcare workers and nonclinical staff at a tertiary hospital: A prevaccine census studyArticle Published on 2022-10-272022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 진단, [키워드] adjusted age Antibody test Asymptomatic category Chemiluminescent assay Comorbidity conducted confidence interval country COVID-19 COVID-19 vaccination determine effective enrolled General population HCW healthcare worker hospital hospital management IgG IgG antibody IgG test implementation increased risk Infection lowest mild symptoms Odds ratio over positive positive PCR test positive SARS-CoV-2 PCR predictor Prevalence preventive measure SAR-CoV-2 SARS-COV-2 infection SARS-CoV-2 nucleocapsid sensitivity Seroprevalence Sex staff Symptoms university was performed [DOI] 10.1371/journal.pone.0267619 PMC 바로가기
Hybrid and vaccine-induced immunity against SAR-CoV-2 in MS patients on different disease-modifying therapiesArticle Published on 2022-10-012022-11-15 Journal: Annals of Clinical and Translational Neurology [Category] COVID19(2023년), SARS, 진단, [키워드] age Analysis antibody Antibody Response assays association cellular cellular response Cellular responses center COVID-19 infection COVID-19 vaccination ELISPOT evaluated examined groups hybrid IFNγ IL-2 immune response immune responses Immunity immunoassay immunologic response independent independent predictor Infection laboratory-confirmed Live virus microneutralization mRNA vaccines multivariate multivariate analyses New York no difference Patient post-vaccination response post-vaccine response receptor recruited SAR-CoV-2 SARS CoV-2 Sex significantly increased subset therapy vaccination Vaccine Vaccine-induced immunity were assessed [DOI] 10.1002/acn3.51664 PMC 바로가기
Synthesis of Potential Antiviral Agents for SARS-CoV-2 Using Molecular Hybridization ApproachArticle Published on 2022-09-122022-11-15 Journal: Molecules [Category] SARS, 치료제, [키워드] agent antiviral property approach computational studies conjugate Conjugates cytotoxicity healthcare hybridization indole investigated molecular Molecular modeling Potential quinoline rhodanine. SAR-CoV-2 SARS-CoV-2 small molecule synthesis virus [DOI] 10.3390/molecules27185923 PMC 바로가기
A How to Guide: Clinical Population Test Development and Authorization of MALDI-ToF Mass Spectrometry-Based Screening Tests for Viral InfectionsArticle Published on 2022-09-032022-11-15 Journal: Viruses [Category] 치료기술, [키워드] applied Applying Asymptomatic asymptomatic screening authorization Bacteria Bacterial CLIA CLIA-LDT clinical clinical process clinical testing COVID-19 criteria detection development diagnostic fungi Infection Laboratory limits MALDI-TOF MS mass MS test overcome pathogenic Population Population screening Proteins regulatory authority SAR-CoV-2 SARS-CoV-2 Screening Systems biology Test viral infection viral infections Viral protein virus viruses [DOI] 10.3390/v14091958 PMC 바로가기
Molecular detection of SARS-CoV-2 and differentiation of Omicron and Delta variant strainsArticle Published on 2022-09-012022-11-15 Journal: Transboundary and emerging diseases [Category] SARS, 변종, 치료기술, [키워드] aa deletion assay B.1.1.529 clinical sample coefficient Coverage COVID-19 Data analysis Delta delta variant detect Detection limit Diagnosis Efficiency genomes Genotype genotypes Human indicated majority molecular Mutation N-gene nasal swab omicron Omicron variant pandemic PCR PCR amplification PCR reaction positive predicted prevalent strain primer probe produced replacing RT-qPCR SAR-CoV-2 SARS-CoV-2 SARS-CoV-2 virus Sequencing Spread Standard standard curve strain Strains Subtypes TaqPath tested The United States Thermofisher variant were used wild-type [DOI] 10.1111/tbed.14497 PMC 바로가기
Maternal and neonatal safety outcomes after SAR-CoV-2 vaccination during pregnancy: a systematic review and meta-analysis임신 중 SAR-CoV-2 백신 접종 후 산모 및 신생아 안전성 결과: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-07-212022-09-11 Journal: BMC Pregnancy and Childbirth [Category] COVID19(2023년), SARS, 치료기술, [키워드] 95%CI Analysis APGAR score bioRxiv Birth weight case-control studies Cochrane Library conducted controlled trials COVID-19 COVID-19 vaccine database died during pregnancy Evidence Fever FIVE Grey literature hemorrhage hospital Hospitalization inception incidence individual Maternal medRxiv Meta-analysis miscarriage Neonatal Newcastle-Ottawa Scale no effect no statistically significant difference outcome OVID patients postpartum hemorrhage Pregnancy problem problems puerperal puerperal fever Randomized controlled trial Randomized controlled trials risk risk of bia Safety SAR-CoV-2 searched square statistically significant difference systematic review vaccination Vaccine Web of Science [DOI] 10.1186/s12884-022-04884-9 PMC 바로가기 [Article Type] Meta-Analysis