Pediatric antibody responses to SARS-CoV-2 after infection and vaccination in Calgary, CanadaResearch Published on 2024-07-182024-09-05 Journal: BMC Infectious Diseases [Category] update2024, [키워드] COVID-19 Hybrid immunity pediatrics SARS-CoV-2 SARS-CoV-2 immunity [DOI] 10.1186/s12879-024-09615-3 PMC 바로가기 [Article Type] Research
Flow Cytometry-Based Measurement of Antibodies Specific for Cell Surface-Expressed Folded SARS-CoV-2 Receptor-Binding DomainsArticle Published on 2024-04-012024-09-05 Journal: Vaccines [Category] update2024, [키워드] Antibody Response COVID-19 flow-cytometry HEK-293T cell lines RBD SARS-CoV-2 SARS-CoV-2 immunity serodiagnosis [DOI] 10.3390/vaccines12040377 PMC 바로가기 [Article Type] Article
Application of a Receptor-Binding-Domain-Based Simple Immunoassay for Assessing Humoral Immunity against Emerging SARS-CoV-2 Virus VariantsArticle Published on 2023-12-012024-09-05 Journal: Biomedicines [Category] update2024, [키워드] ELISA omicron SARS-CoV-2 immunity SARS-CoV-2 variants Spike-RBD virus neutralizing [DOI] 10.3390/biomedicines11123193 PMC 바로가기 [Article Type] Article
SARS-CoV-2-specific nasal IgA wanes 9 months after hospitalisation with COVID-19 and is not induced by subsequent vaccinationArticle Published on 2023-01-012023-07-11 Journal: EBioMedicine [Category] COVID19(2023년), [키워드] convalescent COVID-19 mucosal immunity Nasal antibody SARS-CoV-2 immunity SARS-CoV-2 variants vaccination [DOI] 10.1016/j.ebiom.2022.104402 PMC 바로가기
Immunogenicity decay and case incidence six months post Sinovac-CoronaVac vaccine in autoimmune rheumatic diseases patientsArticle Published on 2022-10-032022-11-15 Journal: Nature Communications [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] anti-SARS-CoV-2 anti-TNF antibody Autoimmune booster dose cellular immunity Control COVID-19 case COVID-19 cases cumulative Decline decrease delta variant dose geometric mean titer IgG positivity IgG response Immunity immunogenicity immunosuppressive Inactivated vaccine incidence individuals Logistic regression analysis male multivariate Neutralizing Neutralizing antibodies outcome Patient patients Prednisone Primary outcome reduce reduction in rheumatic disease SARS-CoV-2 IgG SARS-CoV-2 immunity secondary Spread stability Therapies Vaccine vaccine dose [DOI] 10.1038/s41467-022-33042-0 PMC 바로가기
Immunological memory to common cold coronaviruses assessed longitudinally over a three-year period pre-COVID19 pandemicArticle Published on 2022-09-142022-11-15 Journal: Cell Host & Microbe [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] antibody Antibody titers Antigen CD4 CD4+ T cell common cold common cold coronavirus common cold Coronaviruses comparable coronavirus Endemic Frequency immune immune memory immune response infection prevalence influence longitudinal analysis magnitude memory outcome pandemic performed RBD-specific IgG response reactivity repeated response responses SARS-CoV-2 SARS-CoV-2 immunity SARS-COV-2 infection Steady state steady state. sustained T cells Vaccine development [DOI] 10.1016/j.chom.2022.07.012 PMC 바로가기
An intranasal lentiviral booster reinforces the waning mRNA vaccine-induced SARS-CoV-2 immunity that it targets to lung mucosaArticle Published on 2022-09-072022-11-15 Journal: Molecular therapy : the journal of the American So [Category] COVID19(2023년), SARS, 변종, 진단, 치료기술, 치료제, [키워드] acute respiratory syndrome adaptive addition anti-Spike IgG B cells Beta boost booster cellular immunity Central nervous system Complete coronavirus coronavirus disease COVID-19 COVID-19 vaccine cross-protective delta variant effective effector memory Host humoral Humoral immunity IgA Immunity immunization induce Infection inflammatory properties intranasal intranasal vaccination intranasally lentiviral lentiviral vaccine lung mice mRNA mucosa mucosal mucosal booster vaccine mucosal immunity nasal non-replicative omicron organism pandemic Protective reducing SARS-CoV-2 SARS-CoV-2 emerging variants of concern SARS-CoV-2 immunity shown specificity susceptible T cell target the SARS-CoV-2 transgenic mice vaccination vaccine candidate variant variants of concern Viral transmission waning anti-COVID-19 immunity. [DOI] 10.1016/j.ymthe.2022.04.016 PMC 바로가기
Nirmatrelvir Use and Severe Covid-19 Outcomes during the Omicron SurgeArticle Published on 2022-09-012022-10-06 Journal: The New England Journal of Medicine [Category] SARS, 변종, 진단, 치료제, [키워드] 95% CI 95% confidence interval acute respiratory syndrome adjusted hazard ratio Adults age association B.1.1.529 B.1.617.2 benefit conditions coronavirus covariate death Effectiveness Efficacy eligibility criteria eligible Hospitalization Nirmatrelvir no evidence of Older omicron outcome Patient Protease inhibitor receive Regression model SARS-CoV-2 SARS-CoV-2 immunity service severe coronavirus disease shown significantly lower sociodemographic factors study period therapy treated patient Treatment untreated patient variant was used were assessed [DOI] 10.1056/NEJMoa2204919 PMC 바로가기 [Article Type] Article
Leveraging South African HIV research to define SARS-CoV-2 immunity triggered by sequential variants of concernArticle Published on 2022-09-012022-11-15 Journal: Immunological reviews [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome African antigenic assays B cell cause Combination coronavirus coronavirus disease COVID-19 cross-reactive cross-reactive antibodies driving elicited Epidemic Frequency genomic highlight HIV HIV vaccine Hybrid immunity immune response Immunity immunogenic immunological immunology Infection mutated variants pandemic platform population immunity Prevent Region Research respiratory viruses respond response responses SARS-CoV-2 SARS-CoV-2 immunity shown South Surveillance the SARS-CoV-2 to define triggered vaccination Vaccine variants variants of concern virus VoC [DOI] 10.1111/imr.13086 PMC 바로가기
Sputnik-V reactogenicity and immunogenicity in the blood and mucosa: a prospective cohort study혈액 및 점막의 스푸트니크-V 반응원성과 면역원성: 전향적 코호트 연구Article Published on 2022-08-012022-09-11 Journal: Scientific Reports [Category] SARS, 임상, 진단, 치료기술, 치료법, [키워드] adverse event adverse events alteration assays baseline Blood blood platelet collected condition correlated COVID-19 COVID-19 vaccine COVID-19 vaccines detectable diagnostic dose Effect Efficacy Elevation elicited Gam-COVID-Vac growth Heterologous immune immunization immunology injection Kazakhstan Local Mild-to-moderate mucosal nasal Nasopharyngeal swab nasopharyngeal swabs oncogene outcome participant performed Platelet count populations potentially life-threatening proportion prospective cohort study Questionnaires reactogenic reactogenicity reduced regimen regulated reported SARS-CoV-2 SARS-CoV-2 immunity seroconversion rate Serum level serum levels subject systemic adverse event systemic reactions the vaccine vaccination Vaccine vector Virus neutralization while [DOI] 10.1038/s41598-022-17514-3 PMC 바로가기 [Article Type] Article