The long-term dynamics of serum antibodies against SARS-CoV-2Article Published on 2022-12-152023-07-11 Journal: PeerJ [Category] COVID19(2023년), [키워드] age antibody production COVID-19 patients Gender immune responses S-UFRJ SARS-CoV-2-specific antibodies Seroconversion Serologic response spike glycoprotein. [DOI] 10.7717/peerj.14547 PMC 바로가기
Comparison of two antibody screening systems for SARS-CoV-2 antibody detection in recovered and vaccinated subjects – test performance and possible indicators for immunityObservational Study Published on 2022-12-012023-07-10 Journal: Journal of Clinical Virology [Category] COVID19(2023년), [키워드] Neutralizing antibodies SARS-CoV-2-specific antibodies Seroconversion T-cell-reactivity test performance. [DOI] 10.1016/j.jcv.2022.105322 PMC 바로가기 [Article Type] Observational Study
Antibody response and intra-host viral evolution after plasma therapy in COVID-19 patients pre-exposed or not to B-cell-depleting agentsArticle Published on 2022-11-012022-11-15 Journal: British Journal of Haematology [Category] SARS, 진단, [키워드] anti-CD20 anti-CD20 therapy Anti-spike anti-Spike IgG antibody antibody kinetics B-cell clinical care clinical status clinical symptom Complete contribute convalescent convalescent plasma COVID-19 patient Decline donors eligible evaluated Follow-up hospitalized COVID-19 patients humoral Humoral immunity IgG Immune escape Immunocompromised Immunocompromised patients Immunoglobulin impair lymphopenia majority management mRNA-based vaccine mRNA-based vaccine plasma mutation rate Patient patients treated plasma receiving SARS-CoV-2 SARS-CoV-2 viral load SARS-CoV-2-specific antibodies severity spike mutations survival therapy titre viral control viral evolution virus clearance WHO whole-genome sequencing Whole-genome sequencing. World Health Organization [DOI] 10.1111/bjh.18450 PMC 바로가기
Genetic and immunologic evaluation of children with inborn errors of immunity and severe or critical COVID-19Article Published on 2022-11-012022-11-15 Journal: The Journal of Allergy and Clinical Immunology [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome Affect antibodies Asymptomatic autoantibody B-cell function children children with COVID-19 complement Complication complications coronavirus coronavirus disease COVID-19 COVID-19 complications COVID-19 disease Critical detectable develop diagnosed Diagnostic Criteria died disease evaluated Genetic genetic cause genetic diagnosis help hypoxemic IFN signaling IFN-I immune immune response Immunity immunodeficiency Inborn error inborn errors of immunity individual infected with SARS-CoV-2 Infection Inflammasome Inflammatory Inflammatory factor Mild Molecular diagnosis Mortality mortality rate MOST multisystem inflammatory syndrome in children (MIS-C) Mutation Neutralizing Patient patients patients with asymptomatic Pediatric patients plasma Pneumonia primary immunodeficiency. reported SARS-CoV-2 SARS-CoV-2-specific antibodies severe COVID-19 disease syndrome tested Treatment Type I IFN was performed were measured whole-exome sequencing [DOI] 10.1016/j.jaci.2022.09.005 PMC 바로가기
One-Year Sustained Cellular and Humoral Immunities in Coronavirus Disease 2019 (COVID-19) Convalescents코로나바이러스 질병 2019(COVID-19) 회복기의 1년 지속 세포 및 체액 면역Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 진단, 치료기술, 치료법, [키워드] antibodies antibody Antigen Asymptomatic cellular chemiluminescence immunoassay circulating cohort study conducted convalescent COVID-19 cytokine detectable disease disease onset disease severity ELISA ELISPOT enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay enzyme-linked immunospot assay feature flow cytometry Humoral immunity IgG antibodies IgM IgM antibody immune immune memory Immunity Immunoglobulin individual intracellular cytokine staining membrane memory Microparticle Mild moderate N proteins neutralization neutralizing antibody neutralizing antibody. nucleocapsid protein Nucleocapsid proteins positive SARS-CoV-2 SARS-CoV-2 spike SARS-CoV-2-specific antibodies SARS-CoV-2-specific IgG SARS-CoV-2-specific T-cell response severe disease specific antibodies specific IgG antibodies T cells T-cell T-cell responses the SARS-CoV-2 was tested were assessed [DOI] 10.1093/cid/ciab884 PMC 바로가기 [Article Type] Article
Immunogenicity and immune-persistence of the CoronaVac or Covilo inactivated COVID-19 Vaccine: a 6-month population-based cohort studyArticle Published on 2022-08-122022-11-15 Journal: Frontiers in Immunology [Category] SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome anti-SARS-CoV-2 antibody antibody Characteristics chronic respiratory disease CoronaVac coronavirus coronavirus disease COVID-19 COVID-19 vaccine COVID-19 vaccines delta variant detectable disease Dynamic changes Effectiveness elicited Emergency use IgM response immunogenicity Immunoglobulin inactivated Inactivated vaccine investigated live SARS-CoV-2 neutralizing antibody nucleocapsid Older age pandemic persistence persistence. population-based cohort Protective Protein pseudovirus recipient responses SARS-CoV-2 SARS-CoV-2 variants SARS-CoV-2-specific antibodies seroconversion rates seroconverted significantly lower the SARS-CoV-2 vaccination Vaccine vaccine dose wildtype [DOI] 10.3389/fimmu.2022.939311 PMC 바로가기
The kinetics and predictors of anti-SARS-CoV-2 antibodies up to 8 months after symptomatic COVID-19: A Czech cross-sectional studyCOVID-19 증상이 나타난 후 최대 8개월까지 항-SARS-CoV-2 항체의 동역학 및 예측인자: 체코 횡단 연구Article Published on 2022-08-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 진단, 치료기술, 치료제, [키워드] 95% CI 95% confidence interval acute phase analyzed anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgG antibody Antibody responses average Course COVID-19 Cox regression model cross-sectional demonstrated determinant determinants HCW HCWs healthcare worker IgG IgG and IgM IgM Immunoglobulin indicate knowledge Neutralizing number of symptom Odds ratio prediction predictor Receptor-binding domain reported responses S1 and S2 SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody serology testing seropositive participant seropositive participants Seropositivity seropositivity. Seven specific antibodies Spike protein subsequent Symptom symptom duration symptom onset symptomatic tested the receptor-binding domain the spike protein time intervals was used [DOI] 10.1002/jmv.27784 PMC 바로가기 [Article Type] Article
Protein sensors combining both on-and-off model for antibody homogeneous assay항체 균질 분석을 위한 온/오프 모델을 결합한 단백질 센서Article Published on 2022-08-012022-09-11 Journal: Biosensors & bioelectronics [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] albumin antibodies antibody Antibody test assays binding biosensor changes in clinical samples Combination core protein Critical demonstrated enzymatic activity enzyme FLAG gp41 HCV hepatitis C hepatitis C virus high signal HIV homogeneous Homogeneous assay Human immunodeficiency virus Human serum albumin immunodeficiency virus individuals NanoLuc phenomenon potential tool potential tools Protein Protein switch. respond SARS-CoV-2-specific antibodies sensor serum serum sample serum samples signal-to-noise ratio specific antibodies working model [DOI] 10.1016/j.bios.2022.114226 PMC 바로가기 [Article Type] Article
Case report: Variant-specific pre-exposure prophylaxis of SARS-CoV-2 infection in multiple sclerosis patients lacking vaccination responses증례 보고: 백신 접종 반응이 없는 다발성 경화증 환자에서 SARS-CoV-2 감염의 변종 특이적 노출 전 예방Case Reports Published on 2022-07-252022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-CD20 treatment antibody cocktail approved Asymptomatic Case report Case series case sery Casirivimab cilgavimab conducted coronavirus coronavirus disease coronavirus disease (COVID-19) COVID-19 infection develop dose European Evidence evidence of FIVE humoral Imdevimab immunomodulatory Immunotherapy impair incidence Infection Initially monoclonal monoclonal antibody multiple sclerosis Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody offered omicron Omicron variant one patient pandemic Patient patients positive RT-PCR predominant prophylactic treatment Prophylaxis receptor reduced respiratory respiratory tract infection response retained Risk factors SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pandemic SARS-CoV-2-neutralizing antibodies SARS-CoV-2-neutralizing antibody SARS-CoV-2-specific antibodies SARS-CoV-2-specific antibody severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) severe adverse event severe adverse events Sotrovimab specific antibodies sphingosine sphingosine-1-phosphate sphingosine-1-receptor modulators (S1PR) sustained Symptom T-cell T-cells the patient the SARS-CoV-2 Tixagevimab Treatment union upper respiratory tract upper respiratory tract infection vaccination vaccination response vaccination. variant were recorded [DOI] 10.3389/fimmu.2022.897748 PMC 바로가기 [Article Type] Case Reports
Virology and immune dynamics reveal high household transmission of ancestral SARS-CoV-2 strain바이러스 및 면역 역학은 조상 SARS-CoV-2 균주의 높은 가정 전염을 나타냅니다Article Published on 2022-07-012022-09-11 Journal: Pediatric allergy and immunology : official public [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료법, [키워드] acute phase Adults age antibodies Antibody Response Antibody responses attack rate Blood characterized children coronavirus COVID-19 Ct values determine family members feature generate highlight household household transmission Households immune immunological immunology index case Infection IQR Isolation key factor Local measure Melbourne Melbourne, Australia mucosal nasopharyngeal Nasopharyngeal swab Neutralizing antibodies Novel coronavirus novel coronavirus. NPs nucleocapsid protein participant PCR PCR positivity PCR testing plasma antibody positive provide respiratory respiratory sample Respiratory samples response Saliva SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antigen SARS-CoV-2 antigens SARS-COV-2 infection SARS-CoV-2 strain SARS-CoV-2 variants SARS-CoV-2 viral load SARS-CoV-2-specific antibodies SARS-CoV-2, household transmission secondary attack rate secondary transmission specific antibodies spike Stool tested Transmission transmission of SARS-CoV-2 Viral Virology [DOI] 10.1111/pai.13824 PMC 바로가기 [Article Type] Article