Designing and characterization of a SARS-CoV-2 immunogen with receptor binding motif grafted on a protein scaffold: An epitope-focused vaccine approach단백질 스캐폴드에 이식된 수용체 결합 모티프가 있는 SARS-CoV-2 면역원의 설계 및 특성화: 에피토프 중심 백신 접근 방식Article Published on 2022-06-012022-09-12 Journal: International journal of biological macromolecules [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] ACE2 angiotensin Antibody Response antigenic approach caused COVID-19 pandemic effective epitope healthcare immunized immunized mice Immuno-focusing induce Infectious disease interferon γ mice natural infection neutralization neutralizing antibody Non-neutralizing antibodies non-neutralizing epitope predominant Protein RBD RBM Receptor binding domain receptor binding motif robust SARS-CoV-2 SARS-COV-2 infection Scaffold sera Spread T cell T cell response the antibody response the disease the spike protein Vaccine [DOI] 10.1016/j.ijbiomac.2022.04.148 PMC 바로가기 [Article Type] Article
Polymer-based nano-therapies to combat COVID-19 related respiratory injury: progress, prospects, and challengesReview Article Published on 2021-04-142023-06-15 Journal: Journal of Biomaterials Science. Polymer Edition [Category] MERS, SARS, [키워드] ARDS COVID-19 hydrogel nanocarrier Polymer respiratory injury Scaffold tissue engineering [DOI] 10.1080/09205063.2021.1909412 PMC 바로가기 [Article Type] Review Article