Sequence signatures within the genome of SARS-CoV-2 can be used to predict host sourceResearch Article Published on 2024-04-042024-09-05 Journal: Microbiology Spectrum [Category] update2024, [키워드] Biomarker discovery COVID-19 machine learning metric learning selection pressure viral host adaptation [DOI] 10.1128/spectrum.03584-23 PMC 바로가기 [Article Type] Research Article
Corrigendum: Genomic evolution of BA.5.2 and BF.7.14 derived lineages causing SARS-CoV-2 outbreak at the end of 2022 in ChinaPublic Health Correction Published on 2024-03-222024-09-05 Journal: Frontiers in public health [Category] update2024, [키워드] China Lineage Mutation SARS-CoV-2 selection pressure [DOI] 10.3389/fpubh.2024.1397325 PMC 바로가기 [Article Type] Public Health Correction
Analysis of SARS-CoV-2 genome evolutionary patternsResearch Article Published on 2024-02-102024-09-05 Journal: Microbiology Spectrum [Category] update2024, [키워드] Evolution Genome Mutation rates SARS-CoV-2 selection pressure vaccination [DOI] 10.1128/spectrum.02654-23 PMC 바로가기 [Article Type] Research Article
The most exposed regions of SARS-CoV-2 structural proteins are subject to strong positive selection and gene overlap may locally modify this behaviorResearch Article Published on 2024-01-142024-09-05 Journal: mSystems [Category] update2024, [키워드] Ka/Ks ratio overlapping genes SARS-CoV-2 selection pressure [DOI] 10.1128/msystems.00713-23 PMC 바로가기 [Article Type] Research Article
Bayesian Molecular Dating Analyses Combined with Mutational Profiling Suggest an Independent Origin and Evolution of SARS-CoV-2 Omicron BA.1 and BA.2 Sub-LineagesArticle Published on 2022-12-122023-07-11 Journal: Viruses [Category] COVID19(2023년), [키워드] COVID-19 Evolutionary rate mutational profiling SARS-CoV-2 Omicron selection pressure TMRCA [DOI] 10.3390/v14122764 PMC 바로가기
Predicting elimination of evolving virus variantsArticle Published on 2022-12-022023-07-10 Journal: Mathematical medicine and biology : a journal of t [Category] COVID19(2023년), [키워드] branching process selection pressure virus evolutionary tree. [DOI] 10.1093/imammb/dqac012
Decoding the effects of spike receptor binding domain mutations on antibody escape abilities of omicron variantsArticle Published on 2022-10-302022-11-15 Journal: Biochemical and Biophysical Research Communication [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] affinities antibodies antibody Antibody binding antibody escape appear approach approved binding affinity binding free energy cause Coverage COVID19 decrease Effect evaluate globe hotspot immune evasion immunogenic Immunogenic hotspot immunoinformatics K417N monoclonal antibody mutant Mutation mutations omicron Omicron variant Omicron variants Omicron variants. Point mutation RBD mutation RBD-specific antibody recent Receptor binding domain reduce reduction in REGN10987 residue selection pressure significantly single mutation the binding affinity therapeutic vaccination variants [DOI] 10.1016/j.bbrc.2022.08.050 PMC 바로가기
Linkages between blood groups and malaria susceptibilityArticle Published on 2022-09-302024-09-09 Journal: J Vector Borne Dis [Category] 말라리아, [키워드] Blood groups malaria selection pressure severity Study design susceptibility. PMC 바로가기
Lockdowns exert selection pressure on overdispersion of SARS-CoV-2 variantsArticle Published on 2022-09-012022-11-16 Journal: Epidemics [Category] COVID19(2023년), SARS, 변종, [키워드] B.1.1.7 caused characterized disease Evolution example in viral infections less lockdown lockdowns mathematical New Non-pharmaceutical interventions overdispersion pandemic Regulation risk SARS-CoV-2 SARS-CoV-2 variant selection pressure social contact social distancing superspreading superspreading events the disease Transmission Variability variant [DOI] 10.1016/j.epidem.2022.100613 PMC 바로가기
SARS-Arena: Sequence and Structure-Guided Selection of Conserved Peptides from SARS-related Coronaviruses for Novel Vaccine DevelopmentSARS-Arena: 새로운 백신 개발을 위한 SARS 관련 코로나바이러스에서 보존된 펩티드의 서열 및 구조 유도 선택Article Published on 2022-07-122022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, 치료법, [키워드] 3D structure affected against SARS-CoV agent Analysis approach can be used case study caused CD8 computational method Computational methods conserved contribute coronavirus COVID-19 disease cross-reactive database development envelope proteins help HLA HLA-Arena HLA-B7 Human human leukocyte antigen humoral Humoral response immune response less leukocyte mitigate MOST Multiple sequence alignment N protein Notebook novel nucleocapsid nucleocapsid protein pandemic peptide peptides pHLA scoring Practitioner practitioners Prevent Protein protein regions protein sequence protein sequence alignment protein sequences Proteins Region related viruses responsible SARS-CoV SARS-CoV viruses SARS-CoV-2 SARS-CoV-2 virus Selection selection pressure Sequence alignment Spike protein structural modeling. susceptible T-cell T-cells target the disease the N protein the SARS-CoV-2 virus the spike protein therapy Vaccine development Vaccines variants viral envelope protein viral strains viruses widespread [DOI] 10.3389/fimmu.2022.931155 PMC 바로가기 [Article Type] Article