ACE2 Expression in Kidney and Testis May Cause Kidney and Testis Infection in COVID-19 PatientsMedicine Published on 2021-01-132022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] ACE2 ACE2 expression angiotensin-converting enzyme 2 Care cause caused Cell contribute country COVID-19 COVID-19 infection dataset domain expresse Follow-up Hospitalization human cells indicated Infection Intervention kidney lesion Leydig cells occurred organs Patient performed Pneumonia RBD receptor recombinant renal tubular cells risk SARS-CoV-2 SARS-CoV-2 spike protein seminiferous Sertoli cells shown Testis These cells Wuhan [DOI] 10.3389/fmed.2020.563893 PMC 바로가기 [Article Type] Medicine
Absence of SARS-CoV-2 in semen of a COVID-19 patient cohortCOVID-19 환자 집단의 정액에서 SARS-CoV-2의 부재Article Published on 2021-01-012022-09-11 Journal: Andrology [Category] SARS, 치료기술, 치료제, [키워드] age angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 approved bioinformatics cell entry Characteristics Chest computed tomography Clinical characteristics Cohort cohort of patient Computed tomography COVID-19 COVID-19 patient determine Diagnosis Evidence fecal global pandemic identify indicate Infection investigated Laboratory laboratory findings male male reproductive system median interval morphology normal ranges Novel coronavirus Patient patients patients with COVID-19 plasma Pneumonia positive recent recovering from COVID-19 recruited reproductive reproductive system SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA Semen semen sample Semen samples seminal plasma Sertoli cells sexual transmission specimens Sperm sperm counts Spread sputum suggested tested the patient triggered unlikely Viral viral RNA load virus were recorded [DOI] 10.1111/andr.12848 PMC 바로가기 [Article Type] Article
Coronavirus Disease-19 Infection: Implications on Male Fertility and ReproductionPhysiology Published on 2020-11-172022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] ACE2 ACE2 and TMPRSS2 alteration angiotensin-converting enzyme-2 carried caused Cell cells coronavirus COVID-19 disease Covid-19 sexual transmission evaluated Evidence expressed expression Fertility Fever host cells immune system infect lack male male fertility and reproduction male genital tract men pandemic provide reproduction respiratory SARS-CoV-2 SARS-CoV-2 gender susceptibility Sertoli cells sexual transmission starting point susceptible testicle TMPRSS2 TMPRSS2 molecule transmembrane serine protease virus [DOI] 10.3389/fphys.2020.574761 PMC 바로가기 [Article Type] Physiology
scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli CellsArticle Published on 2020-04-092022-10-31 Journal: Cells [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 category cell entry receptor China coronavirus COVID-19 patient digestive downregulated enrichment Evidence expression pattern Gene ontology GO term GSEA Human indicate Infection male Novel coronavirus pathophysiology Presence Profiling provided rapidly spreading disease reproductive SARS-CoV SARS-CoV-2 SARS-COV-2 infection scRNA-seq sequence similarity Sertoli Sertoli cells single-cell transcriptomes spermatogonia target Teste Transmission Wuhan [DOI] 10.3390/cells9040920 PMC 바로가기 [Article Type] Article