severe acute respiratory syndrome Coronavirus – Communicable Diseases Research

SARS-CoV-2 shedding dynamics and transmission in immunosuppressed patients

면역 억제 환자의 SARS-CoV-2 발산 역학 및 전파

Article

Published on 2022-12-012022-09-11
Journal: Virulence
[Category] COVID19(2023년), SARS, 변종, 치료기술,

An engineered 5-helix bundle derived from SARS-CoV-2 S2 pre-binds sarbecoviral spike at both serological- and endosomal-pH to inhibit virus entry

SARS-CoV-2 S2에서 파생된 조작된 5나선 번들은 바이러스 진입을 억제하기 위해 혈청학적 pH와 엔도솜 pH 모두에서 사베코바이러스 스파이크를 사전 결합합니다.

Article

Published on 2022-12-012022-09-11
Journal: Emerging Microbes & Infections
[Category] COVID19(2023년), SARS, 변종,

[키워드] 5-helix bundle (5HB) acute respiratory syndrome acute respiratory syndrome coronavirus bind binding Broad-spectrum inhibition can not cell membrane construction coronavirus Evidence feature fusion heptad repeat highlighting host cell host cells IC50 infections inhibit neutralize peptide peptides pre-fusion predominant Protein sarbecovirus sarbecovirus Sarbecoviruses SARS-CoV-2 SARS-CoV-2 pseudovirus SARS-CoV-2 S2 SARS-CoV-2 variant SARS-CoV-2 variants serological severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 structural basis These data Treatment viral entry viral entry. viral spike virus entry virus infection
[DOI] 10.1080/22221751.2022.2095308 PMC 바로가기 [Article Type] Article

Severity of SARS-CoV-2 Omicron BA.2 infection in unvaccinated hospitalized children: comparison to influenza and parainfluenza infections

예방접종을 받지 않은 입원 소아에서 SARS-CoV-2 Omicron BA.2 감염의 심각도: 인플루엔자 및 파라인플루엔자 감염과의 비교

Article

Published on 2022-12-012022-09-11
Journal: Emerging Microbes & Infections
[Category] COVID19(2023년), SARS, 변종,

[키워드] 95%CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjusted Admission children Clinical outcome coronavirus COVID-19 COVID-19 infection Croup database death had no hospitalisation hospitalisations Hospitalization Hospitalized Infection Influenza Influenza virus initial investigated Mild neurological Neurological complication Neurological complications occurred omicron outcome parainfluenza parainfluenza virus proportion Public Hospital Relative risk required respiratory. retrieved risk SARS-CoV-2 severe acute respiratory syndrome Coronavirus severity uninfected upper airway upper airways vaccination variant viral infections virus viruses were recorded
[DOI] 10.1080/22221751.2022.2093135 PMC 바로가기 [Article Type] Article

SARS-CoV-2 pseudovirus enters the host cells through spike protein-CD147 in an Arf6-dependent manner

SARS-CoV-2 슈도바이러스는 Arf6 의존적 방식으로 스파이크 단백질-CD147을 통해 숙주 세포에 들어갑니다.

Article

Published on 2022-12-012022-09-11
Journal: Emerging Microbes & Infections
[Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approach Arf6 blockade CD147 cells clathrin Clathrin-mediated endocytosis clinically coronavirus endocytic endocytic mechanism endocytosis evaluate feasible function host cell host cells Huh-7 cell Huh-7 cells independent independent of indicated infected Vero E6 cells Infection inhibited inhibitor knockdown Localization macropinocytosis pathway Prevent pseudovirus pseudovirus infection public health RAB5A SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection SARS-CoV-2 pseudovirus SARS-CoV-2 pseudovirus infection severe acute respiratory syndrome Coronavirus Spike protein spike protein. Spread the SARS-CoV-2 variant Vero E6 VERO E6 cells viral infection weakened
[DOI] 10.1080/22221751.2022.2059403 PMC 바로가기 [Article Type] Article

Research progress on vaccine efficacy against SARS-CoV-2 variants of concern

우려되는 SARS-CoV-2 변이체에 대한 백신 효능 연구 진행

Review

Published on 2022-11-302022-09-11
Journal: Human vaccines & immunotherapeutics
[Category] COVID19(2023년), SARS, 변종,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus addition caused contributed coronavirus COVID-19 COVID-19 vaccine declined Delta Efficacy Epidemic epidemic wave Epidemics Health Organization Immune escape Measures Neutralizing Neutralizing antibodies omicron Omicron variants pathogenicity Prevention and control Protective Research research and development SARS-CoV-2 SARS-CoV-2 variant severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 triggered vaccination Vaccine vaccine efficacy variant Variant of concern. variants variety VoC VOCs WHO World Health Organization
[DOI] 10.1080/21645515.2022.2057161 PMC 바로가기 [Article Type] Review

Binding and neutralizing abilities of antibodies towards SARS-CoV-2 S2 domain

SARS-CoV-2 S2 도메인에 대한 항체의 결합 및 중화 능력

Article

Published on 2022-11-302022-09-11
Journal: Human vaccines & immunotherapeutics
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibodies antibody B.1.1.7 B.1.351 B.1.617.2 B.1.621 binding binding activity carried conserved convalescent patient coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 determined by domain ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated Evidence Immune escape immune protection mAb mAbs MERS MERS-CoV Middle East Middle East respiratory syndrome Middle East respiratory syndrome Coronavirus molecular monoclonal antibodies monoclonal antibody N Terminal N terminal domain NAbs Neutralization assay neutralization assay. Neutralizing Neutralizing activity Neutralizing antibodies neutralizing antibody NTD P.1 Protein pseudo-virus RBD Receptor binding domain reported Research respiratory Result S protein S proteins S2 protein S2 subunit SARS-CoV SARS-CoV-2 SARS-CoV-2 RBD SARS-CoV-2 S SARS-CoV-2 S2 SARS-CoV-2 WT Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus significantly specific antibodies subunit target targets terminal Vaccine design variant variants wild-type
[DOI] 10.1080/21645515.2022.2055373 PMC 바로가기 [Article Type] Article

Analysis of the mutation dynamics of SARS-CoV-2 genome in the samples from Georgia State of the United States

미국 조지아주 샘플에서 SARS-CoV-2 게놈의 돌연변이 역학 분석

Article

Published on 2022-10-202022-09-11
Journal: Gene
[Category] COVID19(2023년), SARS, 변종, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Algorithm Amino acid analysis Analysis caused China clade clades Complete coronavirus disease Coronavirus disease 2019 Coronavirus-2 country Course COVID-19 D614G determine disease England Europe Filter Genome genome sequence Genome sequences Host indicate limit majority Multiple Multiple studies mutated Mutation N501Y NCBI database Novel coronavirus novel coronavirus SARS-CoV-2 nucleotide nucleotides online tool over P681H pandemic Phylogenetic Quality control reference genome SARS-CoV-2 SARS-CoV-2 genome SARS-CoV2 sequence Sequence alignment sequenced genomes sequences severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severe acute respiratory syndrome coronavirus-2. Spread state survival the United State the WHO translation Transmission variant variants virus was used Wuhan
[DOI] 10.1016/j.gene.2022.146774 PMC 바로가기 [Article Type] Article

Theoretical investigation on the interactions of microplastics with a SARS-CoV-2 RNA fragment and their potential impacts on viral transport and exposure

SARS-CoV-2 RNA 단편과 미세 플라스틱의 상호 작용 및 바이러스 수송 및 노출에 대한 잠재적 영향에 대한 이론적 조사

Article

Published on 2022-10-102022-09-11
Journal: The Science of the total environment
[Category] COVID19(2023년), SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Affect affinity Behavior Behavior and fate cause condition coronavirus coronavirus disease Coronavirus disease-19 COVID-19 determine electrostatic environmental conditions Environmental pollution Evidence exposure to facilitate FIVE greater HBV hepatitis B Hepatitis B virus Human hydrophobic Impact independent independent of inherent Interaction involved Lungs mechanism media Microplastic pollution microplastics molecular molecular dynamic simulations molecular interaction molecular volume Nucleic acid material pandemic pandemic spread parameter polar risk RNA RNA fragment SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 transmission SARS-CoV-2. severe acute respiratory syndrome Coronavirus Spread strong interaction surface area temperature the SARS-CoV-2 Transport vacuum virus water
[DOI] 10.1016/j.scitotenv.2022.156812 PMC 바로가기 [Article Type] Article

An impedimetric biosensor for COVID-19 serology test and modification of sensor performance via dielectrophoresis force

유전영동력을 통한 센서 성능 수정 및 COVID-19 혈청학 테스트를 위한 방해계 바이오센서

Article

Published on 2022-10-012022-09-11
Journal: Biosensors & bioelectronics
[Category] COVID19(2023년), SARS, 치료기술, 치료제,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 anti-S antibody antibody Antibody detection Antibody test assistance AuNP binding buffer causative agent caused Concentration conjugate coronavirus coronavirus disease Coronavirus disease 2019 COVID COVID-19 COVID-19 antibody COVID-19 serology test described detect Dielectrophoresis force digit faster gold Gold interdigitated electrodes Gold nanoparticles human sera IDE immunization impedance Impedimetric biosensor. limit of detection Modification morbidity and mortality non-specific phenomenon point-of-care solution Protein purified reached responses SARS-CoV-2 secondary antibody sensitivity sensor sera serology serology test serology tests serum severe acute respiratory syndrome Coronavirus Spectroscopy spike the disease therapeutic time-consuming
[DOI] 10.1016/j.bios.2022.114476 PMC 바로가기 [Article Type] Article

Genomic diversity of SARS-CoV-2 in Pakistan during the fourth wave of pandemic

전염병의 네 번째 물결 동안 파키스탄에서 SARS-CoV-2의 게놈 다양성

Article

Published on 2022-10-012022-09-11
Journal: Journal of medical virology
[Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘,

[키워드] A222V acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affected Alpha B.1.617.2 Beta variant characteristic circulating circulation conducted coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 D950N delta variant Delta variants exhibited followed by G142D genomic Genomic surveillance Germany globe highlight Illumina isolate isolates Karachi L452R lineages P681R Pakistan pandemic Patient Phylogenetic analysis SARS-CoV-2 SARS-CoV-2 strain severe acute respiratory syndrome Coronavirus Singapore spike mutation T19R T478K United Kingdom V483A variant variants variants of concern variants of concern. whole-genome sequencing
[DOI] 10.1002/jmv.27957 PMC 바로가기 [Article Type] Article