A systematic review and meta-analysis of the IgA seroprevalence in COVID-19 patients: Is there a role for IgA in COVID-19 diagnosis or severity?COVID-19 환자의 IgA 혈청 유병률에 대한 체계적인 검토 및 메타 분석: COVID-19 진단 또는 중증도에서 IgA의 역할이 있습니까?Meta-Analysis Published on 2022-10-012022-09-11 Journal: Microbiological research [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] Abstract acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antibody association asymptomatic patients Biomarker caused coronavirus coronavirus disease COVID-19 COVID-19 diagnosis COVID-19 disease determine diagnostic diagnostic test diagnostic tests disease Efficacy Health health problems Humoral response humoral responses IgA Immunity in some include Infection manuscript Meta-analysis Mild observé Patient problems produced Research respiratory SARS-CoV-2 SARS-CoV-2 PCR Seroprevalence severe acute respiratory syndrome Coronavirus Severe patient severe patients severity susceptibility symptomatic systematic review Vaccines [DOI] 10.1016/j.micres.2022.127105 PMC 바로가기 [Article Type] Meta-Analysis
Characteristics and outcomes of SARS-COV 2 critically ill patients after emergence of the variant of concern 20H/501Y.V2: A comparative cohort studyArticle Published on 2022-09-302022-11-16 Journal: Medicine [Category] SARS, 변종, [키워드] 24 hours 95 % CI 95% CI 95% confidence interval absence Admission Analysis change Characteristics cohort of patient cohort study Complete coronavirus 2 Critical care Critically ill patient demographic data dominant expected Fever forest higher risk ICU immunological improvement increased risk Indian Ocean indicated intensive care Invasive mechanical ventilation island less Lineage management Mayotte Mortality outcome outcomes Patient patients performed respiratory Respiratory failure SARS-CoV-2 second wave severe patients severity suggested survival Transmissibility unique VAP variant Ventilator-associated pneumonia Viral genome sequencing VoC [DOI] 10.1097/MD.0000000000030816 PMC 바로가기
Contribution of Coronavirus-Specific Immunoglobulin G Responses to Complement Overactivation in Patients with Severe Coronavirus Disease 2019Article Published on 2022-09-132022-11-15 Journal: The Journal of Infectious Diseases [Category] SARS, 진단, [키워드] Activation acute respiratory syndrome addition Analysis and antibodies antibody C1q circulating classical classical pathway common cold common cold coronavirus common cold Coronaviruses complement complement system coronavirus coronavirus disease correlated COVID-19 Critical demonstrated develop disease disease severity greater healthy control hospitalized patient IgG response immune complex Immunoglobulin Immunoglobulin G implicated mechanism moderate modify outcome overactivation Pathogenesis Patient patients with COVID-19 plasma response responsible RNA SARS-CoV-2 severe COVID-19 severe patients severity systemically therapeutic strategy with COVID-19 [DOI] 10.1093/infdis/jiac091 PMC 바로가기
Ozone as an adjuvant therapy for COVID-19: A systematic review and meta-analysisResearch article Published on 2022-09-012022-10-05 Journal: International immunopharmacology [Category] 임상, [키워드] 95% CI adjuvant therapy Admission adverse event article benefit C-reactive protein case control study clinical Cochrane Library conducted COVID-19 COVID-19 patients CRP D-dimer D-dimer levels decrease endpoints evaluate Hospital stay ICU ICU admission IL-6 IMPROVE improvement integrative medicine intensive care Laboratory laboratory parameter lactate dehydrogenase LDH management Meta-analysis Mortality objective outcomes Ozone ProQuest random-effects Randomized controlled trial RCTs reduction reported Result safety profile SARS-CoV-2 Serious Adverse Event severe patients Side effect significantly SMD Standard therapy suggested systematic review therapy viral clearance were assessed [DOI] 10.1016/j.intimp.2022.109014 [Article Type] Research article
Immune modulation as a consequence of SARS-CoV-2 infectionArticle Published on 2022-08-302022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, [키워드] adaptive Alter alteration B cells CD3 CD8 Clinical severity clinically COVID-19 COVID-19 pathogenesis Cytokine storm D-dimer levels Decreased detrimental effects diagnosed elevated Elevation enrolled Frame healthy controls IFN-γ IgA level IgG IL-10 IL-6 IL-8 ILCs immune immune response Immunity Mild moderate modulated modulation negative correlation NK cell NK cells Patient Plasma cell pro-inflammatory cytokine Protective reduced reduction SARS-CoV-2 SARS-COV-2 infection Serum level severe COVID-19 disease Severe patient severe patients significantly subset T cell T cells the disease TNF-α [DOI] 10.3389/fimmu.2022.954391 PMC 바로가기
Untargeted lipidomics reveals specific lipid profiles in COVID-19 patients with different severity from Campania region (Italy)비표적 지질학은 캄파니아 지역(이탈리아)과 중증도가 다른 COVID-19 환자의 특정 지질 프로필을 보여줍니다Article Published on 2022-08-052022-09-11 Journal: Journal of pharmaceutical and biomedical analysis [Category] MERS, 바이오마커, [키워드] acute respiratory syndrome alteration applied approaches blood sample Blood samples Campania cause Ceramides characterized clinical phenotype Cohort collected comparable contrary Control controls correspondence COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients dataset decrease disease dysregulation highlight Hospital admission increase in Infection Italian Italy Lipid Lipidomics Liquid chromatography longitudinal population mass spectrometry Mild Modification MONITOR outcome Patient patients platform Potential biomarker predict profile respiratory reveal reversed Severe acute respiratory syndrome severe patients severity significantly subset TGs trajectory Trapped ion mobility UHPLC Untargeted. [DOI] 10.1016/j.jpba.2022.114827 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection induces soluble platelet activation markers and PAI-1 in the early moderate stage of COVID-19SARS-CoV-2 감염은 COVID-19의 초기 중등도 단계에서 가용성 혈소판 활성화 마커 및 PAI-1을 유도합니다Article Published on 2022-08-012022-09-11 Journal: International journal of laboratory hematology [Category] MERS, SARS, 바이오마커, [키워드] activated activated partial thromboplastin time activation of platelet activation of platelets Analysis aPTT CD40 ligand Coagulation coagulation dysfunction coagulation factor Coagulation factors Coagulation system coagulation test coagulation tests Comorbidity correlated COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity D-dimer dysfunction dysregulated elevated Factor fibrinogen flow cytometry FXIII help hospitalized COVID-19 patient hospitalized COVID-19 patients induce inhibitor intensive care limit marker moderate Moderate COVID-19 molecular Multiplex assay P-selectin partial thromboplastin time Pathogenesis pathogenesis of COVID-19 pathway performed plasma plasminogen Platelet platelet activation Platelets Pneumonia progression prothrombin Prothrombin time recruited reduction in required SARS-COV-2 infection severe cases severe COVID-19 severe patients severity significantly Stage TFPI the disease Thromboembolism THROMBOPLASTIN Thromboprophylaxis tissue Tissue Factor tissue factor pathway inhibitor tissue plasminogen activator [DOI] 10.1111/ijlh.13829 PMC 바로가기 [Article Type] Article
Delayed intubation is associated with mortality in patients with severe COVID-19: A single-centre observational study in SwitzerlandObservational Study Published on 2022-08-012022-10-04 Journal: Anaesthesia, critical care & pain medicine [Category] 임상, [키워드] acute respiratory distress syndrome Analysis Characteristics conducted COVID-19 Delayed delayed intubation distress First wave Geneva University Hospitals Hospital admission ICU ICU admission ICU patient increased mortality intensive care intensive care unit Intubated intubation management Mortality Patient prospective observational study randomised controlled trial required Respiratory failure second wave severe COVID-19 severe patients severity significantly significantly higher subsequent Switzerland the timing timing intubation. Treatment [DOI] 10.1016/j.accpm.2022.101092 PMC 바로가기 [Article Type] Observational Study
Are lipid ratios and triglyceride-glucose index associated with critical care outcomes in COVID-19 patients?지질 비율과 트리글리세리드-글루코스 지수는 COVID-19 환자의 중환자 치료 결과와 관련이 있습니까?Article Published on 2022-08-012022-09-11 Journal: PLoS ONE [Category] 바이오마커, [키워드] adjusted age Analysis biochemical marker biochemical markers BMI carried cholesterol coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 mortality COVID-19 patient Critical care demonstrated evaluate Glucose HDL-C high-density insulin insulin resistance LDL-C Lipid lipoprotein Logistic regression analysis low-density Low-density lipoprotein Mortality multivariate multivariate logistic regression analysis outcome performed predictor Prognosis Regression regression models Research severe coronavirus disease Severe patient severe patients severity Sex significantly higher significantly lower statistically survivor Total cholesterol Triglyceride with COVID-19 [DOI] 10.1371/journal.pone.0272000 PMC 바로가기 [Article Type] Article
Serum SARS-CoV-2 Antigens for the Determination of COVID-19 SeverityCOVID-19 중증도 결정을 위한 혈청 SARS-CoV-2 항원Article Published on 2022-07-282022-09-11 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Antigen antigenic Antigenic assay Chemiluminescent assay CLIA COVID-19 COVID-19 diagnosis Determination diagnostic disease severity evaluate false-negative false-negative results followed by help intensive care Kinetics likelihood ratio marker N antigen nasopharyngeal non-severe patient non-severe patients onset of symptoms Patient performed polymerase chain reaction polymerase chain reactions positive Prognosis prognosis test. progression provided reverse transcriptase risk RT-PCR RT-PCRs SARS-CoV-2 SARS-COV-2 infection sensitive serum severe and non-severe patients severe COVID-19 severe patients severity Simoa swabs the WHO threshold transcriptase Viremia was determined were measured WHO Clinical Progression Scale [DOI] 10.3390/v14081653 PMC 바로가기 [Article Type] Article