Patients Withdrawing Dupilumab Monotherapy for COVID-19-Related Reasons Showed Similar Disease Course Compared With Patients Continuing Dupilumab TherapyCOVID-19 관련 이유로 두필루맙 단독 요법을 중단한 환자는 두필루맙 요법을 계속하는 환자와 유사한 질병 경과를 보였다Article Published on 2022-05-012022-09-12 Journal: Dermatitis : contact, atopic, occupational, drug [Category] MERS, 진단, [키워드] Dupilumab reason Showed [DOI] 10.1097/DER.0000000000000814 PMC 바로가기 [Article Type] Article
Freedom to Stay-at-Home? Countries Higher in Relational Mobility Showed Decreased Geographic Mobility at the Onset of the COVID-19 PandemicPsychology Published on 2021-09-272022-10-31 Journal: Frontiers in Psychology [Category] COVID-19, [키워드] changes in composed country COVID-19 COVID-19 pandemic Culture decrease Decreased GDP Geographic geographic mobility independent individual information Mobility Onset provided reduce relational mobility restrict Showed social behavior social environment [DOI] 10.3389/fpsyg.2021.648042 PMC 바로가기 [Article Type] Psychology
Nine Cases of SARS-CoV-2-PCR-positive Samples Showed No Increase of Antibodies Against SARS-CoV-2SARS-CoV-2-PCR 양성 샘플 9건에서 SARS-CoV-2에 대한 항체 증가 없음Article Published on 2021-09-012022-09-12 Journal: In vivo (Athens, Greece) [Category] SARS, 진단, [키워드] absence activating adaptive affecting Against analyzed anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibodies Care collected coronavirus 2 COVID-19 hospital IgG immune reaction increase innate immune Innate immunity Japan Nurse outbreak PCR-positive provide respiratory RT-qPCR Sample SARS-CoV-2 sera serum sample Showed virus [DOI] 10.21873/invivo.12587 PMC 바로가기 [Article Type] Article
A Potent Leukocyte Transmigration Blocker: GT-73 Showed a Protective Effect against LPS-Induced ARDS in Mice강력한 백혈구 변환 차단제 : GT-73은 마우스에서 LPS- 유도 된 ARD에 대한 보호 효과를 나타냈다.Article Published on 2021-07-292022-08-31 Journal: Molecules [Category] SARS, 바이오마커, [키워드] acute respiratory distress acute respiratory distress syndrome addition Adhesion Molecule affecting applied ARDS BALF bind biochemical blocked blocker Blood blood cell Bronchoalveolar lavage fluid caused cell adhesion molecule covalent inhibitor COVID-19 patient COVID-19 patients Critical Cytokine storm derivatives drug candidate Effect Endothelial cell evaluate finding histological IL-1β IL-6 infiltrating Inflammation investigated leukocyte leukocyte transmigration leukocytes lung Lungs MCP-1 Migration molecule Mortality mouse model PECAM-1 peripheral tissues Platelet potent prodrug rationale reduced respiratory distress Respiratory distress syndrome responsible Showed significantly syndrome TERT transendothelial migration transmigration Treatment unique was tested was used White blood cell [DOI] 10.3390/molecules26154583 PMC 바로가기 [Article Type] Article
Combining a Fusion Inhibitory Peptide Targeting the MERS-CoV S2 Protein HR1 Domain and a Neutralizing Antibody Specific for the S1 Protein Receptor-Binding Domain (RBD) Showed Potent Synergism against Pseudotyped MERS-CoV with or without Mutations in RBDArticle Published on 2019-01-062022-10-28 Journal: Viruses [Category] Coronavirus, [키워드] Administered antiviral activity clinics Combination domain Efficacy exhibited fusion HR1 domain Infection inhibiting inhibitory m336 MERS-CoV MERS-CoV infection MERS-CoV pseudovirus MERS-CoV-infected patients Middle East monoclonal antibody Mutation Neutralizing neutralizing antibody peptide potent Prevent public health RBD reduced respiratory syndrome coronavirus resulting S2 protein Showed Specific Spike protein strain synergism targeting the RBD treat Treatment Vaccine [DOI] 10.3390/v11010031 PMC 바로가기 [Article Type] Article