Mathematical Modeling of SARS-CoV-2 Omicron Wave under Vaccination EffectsArticle Published on 2024-06-142024-09-05 Journal: Computation (Basel, Switzerland) [Category] update2024, [키워드] mathematical modeling omicron wave SARS-CoV-2 variant scenarios Simulations vaccination [DOI] 10.3390/computation11020036 PMC 바로가기 [Article Type] Article
Addressing Hospital Overwhelm During the COVID-19 Pandemic by Using a Primary Health Care–Based Integrated Health System: Modeling StudyOriginal Paper Published on 2024-06-032024-09-05 Journal: JMIR Medical Informatics [Category] update2024, [키워드] BED beds death deaths develop development health system health systems hospital hospital overwhelm hospitals integrated management Model modeling study Mortality overwhelm pandemic policy mix primary care Primary Health Care service services Simulation Simulations [DOI] 10.2196/54355 PMC 바로가기 [Article Type] Original Paper
A Generative Pretrained Transformer (GPT)–Powered Chatbot as a Simulated Patient to Practice History Taking: Prospective, Mixed Methods StudyOriginal Paper Published on 2024-01-162024-09-05 Journal: JMIR Medical Education [Category] update2024, [키워드] answer answers artificial intelligence chatbot chatbots ChatGPT Conversational Agent conversational agents documentation generative pretrained transformer GPT history history taking Human computer human machine interactive medical education natural language processing NLP response responses Satisfaction simulated simulated patient Simulation Simulations Usability [DOI] 10.2196/53961 PMC 바로가기 [Article Type] Original Paper
A systematic review of mechanistic models used to study avian influenza virus transmission and controlarticle Published on 2023-10-182024-09-05 Journal: Veterinary Research [Category] update2024, [키워드] Avian Influenza control strategies disease transmission Dynamics modeling poultry Simulations systematic review [DOI] 10.1186/s13567-023-01219-0 PMC 바로가기 [Article Type] article
A causal roadmap for generating high-quality real-world evidencearticle Published on 2023-09-222024-09-05 Journal: Journal of Clinical and Translational Science [Category] update2024, [키워드] Causal inference Estimands machine learning Real-world evidence sensitivity analysis Simulations [DOI] 10.1017/cts.2023.635 PMC 바로가기 [Article Type] article
Identification of natural products against enoyl-acyl-carrier-protein reductase in malaria via combined pharmacophore modeling, molecular docking and simulations studiesArticle Published on 2023-03-312024-09-10 Journal: J Biomol Struct Dyn [Category] 말라리아, [키워드] docking Enoyl-acyl carrier protein reductase Güner-Henry and enrichment studies multicomplex-based pharmacophore modeling Simulations test set validation. PMC 바로가기
A hybrid discrete-continuum model of immune responses to SARS-CoV-2 infection in the lung alveolar region, with a focus on interferon induced innate responseArticle Published on 2022-12-212022-11-15 Journal: Journal of theoretical biology [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] adaptive alveolar alveolar cells antibodies antibody antibody concentration baseline Cell cell death Cellular automaton COVID-19 develop diffusion domain Efficacy Future Gas exchange healthy human lung Immune cell immune protection immune response Immunity infected cell Infection initial Innate innate immune Innate immunity innate response Interaction interferon interferons lung alveolar maintain manuscript mechanism Model multiple mechanism outcome Pneumonia produced profiles progression Result RNA copy SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 variant Simulations Spread Strains submitted switching T cells the SARS-CoV-2 virus two-dimensional type I Viral load virion virions [DOI] 10.1016/j.jtbi.2022.111293 PMC 바로가기
Vaccine models predict rules for updating vaccines against evolving pathogens such as SARS-CoV-2 and influenza in the context of pre-existing immunityArticle Published on 2022-10-032022-11-16 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 변종, [키워드] Affect Analysis approach benefit circulating variant circulating variants complex COVID-19 dissect H5N1 Immunity individuals induce influence Influenza Influenza virus modeling omicron pathogen pre-existing immunity predict recall response SARS-CoV-2 SARS-CoV-2 vaccine Simulations Vaccine Vaccines variants [DOI] 10.3389/fimmu.2022.985478 PMC 바로가기
Impact of potential modifications to Alzheimer’s disease clinical trials in response to disruption by COVID-19: a simulation studyCOVID-19에 의한 혼란에 대한 반응으로 알츠하이머 병 임상 시험에 대한 잠재적 수정의 영향 : 시뮬레이션 연구Research Published on 2021-12-202022-09-10 Journal: Alzheimer's Research & Therapy [Category] SARS, 치료기술, [키워드] accounted adaptive affected Alzheimer Alzheimer disease Alzheimer’s disease Analysis assessments biases change changes changes in Changing clinical trial clinical trials completion COVID-19 COVID-19 pandemic datasets detect disease Disease modification Effect effect size Enrollment examined expected idea Impact investigator investigators linear maintain Mild cognitive impairment Modification outcome outcomes pandemic performed randomized clinical trial RCT RCTs Result risk Simulation Simulations Sponsor Statistical power Support symptomatic Symptomatic treatment threat Threats Treatment treatment period Trial trials Validity was determined [DOI] 10.1186/s13195-021-00938-w PMC 바로가기 [Article Type] Research
COVID-19 Critical Care Simulations: An International Cross-Sectional SurveyPublic Health Published on 2021-09-212022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] average Care Characteristics conducted country COVID-19 COVID-19 patient CPR cross-sectional delivery facilitators Factor Frequency HCW HCWs healthcare healthcare preparedness Healthcare system healthcare worker Healthcare workers hospital ICU infection control International international survey intubation main outcome measure Measures MOST mother Neonatal outcome Participants Patient positive regions reported Research Respiratory failure Safe Simulation Simulations survey Transport utility WHO [DOI] 10.3389/fpubh.2021.700769 PMC 바로가기 [Article Type] Public Health