The effect of Nutrition Bio-shield superfood (NBS) on disease severity and laboratory biomarkers in patients with COVID-19: A randomized clinical trialArticle Published on 2022-11-012022-11-15 Journal: Microbial pathogenesis [Category] SARS, 바이오마커, [키워드] ALP assigned baseline body temperature can be used clinical clinical trial Clinical trial study control group COVID-19 COVID-19 disease COVID-19 disease severity CPK CRP determine dimer disease severity Effect effective ELISA kit ESR IL-6 immune system IMPROVE Intervention intervention group Iran laboratory biomarker laboratory biomarkers laboratory parameter LDH lymphocyte Lymphocyte count nutrition Nutrition bio-shield superfood. oxygen saturation Patient patients with COVID-19 performed Placebo Randomized randomized clinical trial receiving Result Serum level serum sample SGOT SGPT significant decrease significant increase single-blind Superfood Tehran tested the mean TNF-α Treatment Trial two group Two-arm variable was performed WBC [DOI] 10.1016/j.micpath.2022.105792 PMC 바로가기
An online breathing and wellbeing programme (ENO Breathe) for people with persistent symptoms following COVID-19: a parallel-group, single-blind, randomised controlled trialRandomized Controlled Trial Published on 2022-09-012022-10-04 Journal: The Lancet. Respiratory Medicine [Category] Fulltext, MERS, 임상, [키워드] 1:1 adverse event Analysis Anxiety approach approaches assigned Block randomisation breathlessness chronic obstructive clinically clinics complementary computer-generated conducted COVID COVID-19 eight element English Generalised anxiety disorder groups Health Imperial College London IMPROVE improvement individual intention-to-treat population Intervention Mental mental health MHC outcome measure parallel-group participant participated Patient physical potential participant Primary outcome pulmonary disease qualitative data randomisation randomised controlled trial Randomly recovering from COVID-19 recruited Registered reported Research researcher responses responsible secondary secondary outcome single-blind statistically significant Symptom thematic analysis treatment group Trial unique usual care usual care group Visual Analogue Scale was done were excluded were given [DOI] 10.1016/S2213-2600(22)00125-4 PMC 바로가기 [Article Type] Randomized Controlled Trial
Efficacy of individualized homeopathy as an adjunct to standard of care of COVID-19: A randomized, single-blind, placebo-controlled studyRandomized Controlled Trial Published on 2022-08-012022-10-05 Journal: Complementary therapies in clinical practice [Category] 신약개발, 임상, [키워드] placebo-controlled study Randomized single-blind Standard of care [DOI] 10.1016/j.ctcp.2022.101602 PMC 바로가기 [Article Type] Randomized Controlled Trial
Satisfaction with modes of telemedicine delivery during COVID-19: A randomized, single-blind, parallel group, noninferiority trialResearch article Published on 2022-07-012022-10-05 Journal: The American journal of the medical sciences [Category] 임상, [키워드] 1:1 95% CI addressed adjusted age analyses Analysis black clinics conducted determine eligible indicated intent-to-treat Intervention majority margin mITT mITT analysis Noninferiority Older outcome parallel group participant Participants Patient satisfaction patients per protocol performed proportion Randomized randomized clinical trial Result Satisfaction single-blind Telemedicine Trial was determined women [DOI] 10.1016/j.amjms.2022.06.021 [Article Type] Research article
An exploratory analysis of the response to ChAdOx1 nCoV-19 (AZD1222) vaccine in males and females남성과 여성에서 ChAdOx1 nCoV-19(AZD1222) 백신에 대한 반응에 대한 탐색적 분석Article Published on 2022-07-012022-09-11 Journal: EBioMedicine [Category] COVID19(2023년), MERS, SARS, 임상, 진단, [키워드] 95% CI Academy adjusted age and sex All participant All participants anti-SARS-CoV-2 anti-Spike IgG AstraZeneca AZD1222 both sexes Brazil Cellular immune response ChAdOx1 ChAdOx1 nCoV-19 Chinese clinical Clinical research clinical trials Coalition Council COVID-19 COVID-19 vaccine COVID-19 vaccines defined dose doses Efficacy endpoints Engineering enrolled Evidence evidence of Exploratory analysis fatigue female females Fever first dose Follow-up foundation funding generate GMR greater headache humoral immune responses immunogenicity immunogenicity data immunological individual Innovation interaction term ISRCTN Linear model linear models log-transformed logistic regression models majority male males Medical Science NAAT nCoV network neutralisation assay NIHR no evidence of nucleic acid nucleic acid amplification nucleic acid amplification test Oxford participant Participants primary endpoint randomised randomised controlled trial reaction reactogenicity receive Registered Regression model reported SARS-COV-2 infection Science Sex Sex-differences shown single-blind South spike IgG Standard dose statistically significant difference Superior symptomatic SARS-CoV-2 infection systemic reaction Telle the primary endpoint titre trial participants vaccination Vaccine vaccine efficacy Vaccines Valley Volunteer [DOI] 10.1016/j.ebiom.2022.104128 PMC 바로가기 [Article Type] Article
The Effects of Theory-Based Educational Intervention and WhatsApp Follow-up on Papanicolaou Smear Uptake Among Postnatal Women in Malaysia: Randomized Controlled TrialRandomized Controlled Trial Published on 2022-06-272022-10-05 Journal: JMIR mHealth and uHealth [Category] 임상, [키워드] analyzed assigned Attitude baseline both group Cancer changed clinical clinics Cluster conducted control group control groups Controlled COVID-19 pandemic demonstrated determine Effect effective Effectiveness Factors first stage Follow-up form Google Health health knowledge high uptake IBM Intervention intervention group intervention study investigated knowledge knowledge score Malaysia mortality rate multifactorial Negeri Sembilan Neoplasms p value Papanicolaou test participant Patient Population Practice previous study primary endpoint proportion Psychological psychological theory questionnaire Randomized controlled trial Randomly reduce registry researcher secondary endpoint Self-efficacy shown Significant single-blind smear social media SPSS standard care statistically significant tested theory uptake uterine uterine cervical neoplasms. was used WhatsApp withdrawn women [DOI] 10.2196/32089 PMC 바로가기 [Article Type] Randomized Controlled Trial
Efficacy and safety of an inactivated whole-virion vaccine against COVID-19, QazCovid-in®, in healthy adults: A multicentre, randomised, single-blind, placebo-controlled phase 3 clinical trial with a 6-month follow-upResearch article Published on 2022-06-252022-10-05 Journal: EClinicalMedicine [Category] 변종, 임상, [키워드] 95% CI Administered adverse events assigned chronic heart failure clinical trial Committee concomitant disease conducted Coronavirus infection COVID-19 COVID-19 case diagnosed dose education effective Efficacy eligible participant finding first dose Follow-up follow-up period funding healthy hydroxide inactivated incidence Infection intramuscular intramuscularly Kazakhstan Local multicenter multicentre not affect observation period Older participant Participants Phase 3 Placebo placebo-controlled Prevent primary endpoint Program Protective randomised Randomly reached receive Registered RT-PCR Safe Science severe COVID-19 short-lived single-blind Spread state symptomatic case the SARS-CoV-2 the SARS-CoV-2 virus the vaccine Trial Vaccine Vaccines virus were recorded [DOI] 10.1016/j.eclinm.2022.101526 [Article Type] Research article
Safety and immunogenicity of the ChAdOx1 nCoV-19 (AZD1222) vaccine in children aged 6-17 years: a preliminary report of COV006, a phase 2 single-blind, randomised, controlled trial6~17세 어린이 대상 ChAdOx1 nCoV-19(AZD1222) 백신의 안전성 및 면역원성: 2상 단일 맹검, 무작위, 대조 시험인 COV006의 예비 보고서Clinical Trial Published on 2022-06-112022-09-11 Journal: Lancet (London, England) [Category] COVID19(2023년), MERS, SARS, 임상, 진단, 치료법, [키워드] 95% CI administration Adults adverse event adverse events age All participants anti-SARS-CoV-2 IgG antibody Antibody titre antibody titres arbitrary unit assigned AstraZeneca AZD1222 baseline capsular Cellular responses ChAdOx1 ChAdOx1 nCoV-19 children chronic respiratory conditions Concentration Controlled trial COVID-19 COVID-19 vaccine COVID-19 vaccines Cutoff Department dose doses Efficacy enrolled Fever first dose first vaccination four group four groups geometric geometric mean geometric mean ratios Geometric means group half-maximal inhibitory concentration Humoral response humoral responses immune response immune responses immunogenic immunogenicity in some intramuscular dose introduced investigators ISRCTN Laboratory laboratory-confirmed Laboratory-confirmed COVID-19 Local nucleocapsid protein Pain and tenderness participant Participants peaked Phase 2 phase 3 study preliminary report Primary outcome prime and boost raised randomised Randomly receive receiving recruitment Registered remained reported resolved respiratory response Safety safety population SARS-CoV-2 second dose second vaccination secondary outcome Serious Adverse Event Serious Adverse Events seronegative seronegative participant seronegative participants seropositive serostatus single-blind stratified study drug study groups tenderness Tolerability treatment allocation Trial vaccination Vaccine Viral viral particle were recorded [DOI] 10.1016/S0140-6736(22)00770-X PMC 바로가기 [Article Type] Clinical Trial
Running an active gaming-based randomized controlled trial during the COVID-19 pandemic: Challenges, solutions and lessons learnedShort communication Published on 2022-06-012022-10-05 Journal: Public Health in Practice [Category] 임상, [키워드] age amplified changed clinical trial COVID-19 COVID-19 pandemic Human subject study increasingly Intervention knowledge objective pandemic Participants positive Randomized Randomized controlled trial recruitment required Research Research protocol researchers Result running single-blind social distancing Study protocol subject transitioned Trial [DOI] 10.1016/j.puhip.2022.100259 [Article Type] Short communication
Accuracy and perceptions of teledentistry in KSA during the COVID-19 pandemic: A single-centre randomised controlled trialResearch article Published on 2022-06-012022-10-05 Journal: Journal of Taibah University Medical Sciences [Category] 임상, [키워드] Accuracy baseline Care clinical examination conditions control group control groups COVID-19 COVID-19 pandemic diagnose diagnoses Diagnosis group had more Health hospital hygiene in-person visit Intervention knowledge lockdown moderate no significant difference objective pandemic parallel-group participant Patient questionnaire randomised randomised clinical trial randomised controlled trial reported Result retrieved significantly single-blind study group subsequent Teledentistry telehealth the study group was used while [DOI] 10.1016/j.jtumed.2021.11.015 [Article Type] Research article