Delivery Strategies of siRNA Therapeutics for Hair Loss TherapyReview Published on 2024-07-112024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] barrier delivery design principle Hair loss siRNA strategic research framework [DOI] 10.3390/ijms25147612 PMC 바로가기 [Article Type] Review
Inhibition of SARS-CoV-2 Replication by Self-Assembled siRNA Nanoparticles Targeting Multiple Highly Conserved Viral SequencesArticle Published on 2024-07-032024-09-05 Journal: Viruses [Category] update2024, [키워드] Replication RNA nanotechnology SARS-CoV-2 siRNA [DOI] 10.3390/v16071072 PMC 바로가기 [Article Type] Article
Principle, application and challenges of development siRNA-based therapeutics against bacterial and viral infections: a comprehensive reviewMicrobiology Review Published on 2024-06-132024-09-05 Journal: Frontiers in Microbiology [Category] update2024, [키워드] delivery systems non-coding RNA RNAi siRNA therapeutic applications [DOI] 10.3389/fmicb.2024.1393646 PMC 바로가기 [Article Type] Microbiology Review
Analysis of the pharmacokinetics and efficacy of RBD1016 – A GalNAc-siRNA targeting Hepatitis B Virus X gene using semi-mechanistic PK/PD modelResearch Article Published on 2024-05-242024-09-05 Journal: Heliyon [Category] update2024, [키워드] GalNAc Hepatitis B virus N-acetyl galactosamine pharmacokinetic Semi-mechanistic model siRNA Small interference RNA [DOI] 10.1016/j.heliyon.2024.e31924 PMC 바로가기 [Article Type] Research Article
A novel multitargeted self-assembling peptide-siRNA complex for simultaneous inhibition of SARS-CoV-2-host cell interaction and replicationOriginal Article Published on 2024-05-242024-09-05 Journal: Molecular Therapy. Nucleic Acids [Category] update2024, [키워드] ACE2 cathepsin B cell-penetrating peptide COVID-19 Integrins MT: Oligonucleotides: Therapies and Applications RGD RNAi SARS-CoV-2 siRNA [DOI] 10.1016/j.omtn.2024.102227 PMC 바로가기 [Article Type] Original Article
Importance of the electrophoresis and pulse energy for siRNA-mediated gene silencing by electroporation in differentiated primary human myotubesResearch Published on 2024-05-162024-09-05 Journal: BioMedical Engineering OnLine [Category] update2024, [키워드] Electrophoresis Electroporation Electrotransfection gene silencing mechanisms Primary human myotubes siRNA [DOI] 10.1186/s12938-024-01239-7 PMC 바로가기 [Article Type] Research
The Efficacy and Safety of Polyethylene Glycol Cholesterol- and Tocopherol Polyethylene Glycol 1000 Succinate-Modified Transforming Growth Factor β1 Small Interfering RNA Lipid Nanoparticles in the Treatment of Paclitaxel-Resistant Non-Small-Cell Lung CancerArticle Published on 2024-01-042024-09-05 Journal: Pharmaceutics [Category] update2024, [키워드] Lipid nanoparticles paclitaxel-resistant non-small-cell lung cancer PEG cholesterol siRNA TGFβ1 tocopherol polyethylene glycol succinate (TPGS) [DOI] 10.3390/pharmaceutics16010075 PMC 바로가기 [Article Type] Article
siRNA targeting Atp5a1 gene encoding ATPase α, the ligand of Peg fimbriae, reduced Salmonella Enteritidis adhesionarticle Published on 2023-12-312024-09-01 Journal: Avian Pathology [Category] 살모넬라증, [키워드] adhesion ATPase α ligand blot Peg fimbriae Salmonella Enteritidis siRNA [Article Type] article
An ncRNA transcriptomics-based approach to design siRNA molecules against SARS-CoV-2 double membrane vesicle formation and accessory genesarticle Published on 2023-12-122024-09-05 Journal: BMC Infectious Diseases [Category] update2024, [키워드] Accessory genes gene silencing ncRNA Non-structural genes Nsps Open Reading frame ORF SARS-CoV-2 siRNA [DOI] 10.1186/s12879-023-08870-0 PMC 바로가기 [Article Type] article
Engineered Polymer-siRNA Polyplexes Provide Effective Treatment of Lung InflammationArticle Published on 2023-10-282024-09-05 Journal: ACS Nano [Category] update2024, [키워드] Anti-inflammatory cytosolic delivery Lung inflammation Polymer Polyplex siRNA [DOI] 10.1021/acsnano.2c08690 PMC 바로가기 [Article Type] Article