In Vitro Generation of Haploid Germ Cells from Human XY and XXY Immature Testes in a 3D Organoid SystemArticle Published on 2024-07-032024-09-05 Journal: Bioengineering [Category] update2024, [키워드] Cancer survivors fertility preservation in vitro Klinefelter syndrome male infertility Organoid spermatogenesis 3D culture spermatogonia spermatogonia stem cells [DOI] 10.3390/bioengineering11070677 PMC 바로가기 [Article Type] Article
High SARS-CoV-2 tropism and activation of immune cells in the testes of non-vaccinated deceased COVID-19 patientsarticle Published on 2023-02-162024-09-05 Journal: BMC Biology [Category] update2024, [키워드] infertility Leydig cell macrophages Nanotechnology renin-angiotensin system SARS-CoV-2 replication Sertoli cell spermatogenesis spermatogonia Testosterone [DOI] 10.1186/s12915-022-01497-8 PMC 바로가기 [Article Type] article
scRNA-seq Profiling of Human Testes Reveals the Presence of the ACE2 Receptor, A Target for SARS-CoV-2 Infection in Spermatogonia, Leydig and Sertoli CellsArticle Published on 2020-04-092022-10-31 Journal: Cells [Category] COVID-19, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 category cell entry receptor China coronavirus COVID-19 patient digestive downregulated enrichment Evidence expression pattern Gene ontology GO term GSEA Human indicate Infection male Novel coronavirus pathophysiology Presence Profiling provided rapidly spreading disease reproductive SARS-CoV SARS-CoV-2 SARS-COV-2 infection scRNA-seq sequence similarity Sertoli Sertoli cells single-cell transcriptomes spermatogonia target Teste Transmission Wuhan [DOI] 10.3390/cells9040920 PMC 바로가기 [Article Type] Article