Inhalation of vaccines and antiviral drugs to fight respiratory virus infections: reasons to prioritize the pulmonary route of administrationarticle Published on 2023-09-282024-09-05 Journal: mBio [Category] update2024, [키워드] Aerosols Antiviral agents dry powder formulation Dry powder inhaler IgA inhalation mucosal immunity Pulmonary administration respiratory viruses SARS-CoV-2 Spray drying Vaccines [DOI] 10.1128/mbio.01295-23 PMC 바로가기 [Article Type] article
Formulation and Scale-Up of Fast-Dissolving Lumefantrine Nanoparticles for Oral Malaria Therapyarticle Published on 2023-08-312024-09-01 Journal: Pathogens [Category] 말라리아, [키워드] Dissolution kinetics Flash NanoPrecipitation HPMCAS Lumefantrine malaria nanocarrier nanoparticle PK Scaleup Spray drying [Article Type] article
Neutralisation of SARS-CoV-2 by monoclonal antibody through dual targeting powder formulationArticle Published on 2023-04-302024-09-05 Journal: Journal of controlled release : official journal o [Category] update2024, [키워드] COVID-19 intranasal delivery Neutralising antibody, pulmonary delivery respiratory viral infections Spray drying [DOI] 10.1016/j.jconrel.2023.04.029 PMC 바로가기 [Article Type] Article
Microfluidic production of mRNA-loaded lipid nanoparticles for vaccine applicationsReview Published on 2022-10-012023-07-10 Journal: Expert opinion on drug delivery [Category] COVID19(2023년), [키워드] drug delivery Lipid nanoparticle microencapsulation Microfluidics mRNA Spray drying Vaccine [DOI] 10.1080/17425247.2022.2135502 [Article Type] Review
Preparation and Characterization of Inhalable Ivermectin Powders as a Potential COVID-19 TherapyArticle Published on 2022-10-012023-07-08 Journal: Journal of Aerosol Medicine and Pulmonary Drug Delivery [Category] COVID19(2023년), [키워드] COVID-19 Dry powder aerosol Inhalable ivermectin Lactose Spray drying [DOI] 10.1089/jamp.2021.0059
Pharmacokinetics and safety of inhaled ivermectin in mice as a potential COVID-19 treatment잠재적인 COVID-19 치료제로서 생쥐에서 흡입된 이버멕틴의 약동학 및 안전성Article Published on 2022-05-102022-09-11 Journal: International journal of pharmaceutics [Category] COVID19(2023년), SARS, 치료법, 치료제, [키워드] administration analyzed Antiviral antiviral efficacy BALB/c mice BALF binding Bronchoalveolar lavage fluid clinically collected Concentration concentrations COVID-19 Critical drug Dry Dry powder aerosol Formulation healthy histological in vitro in vitro experiment Inhalable ivermectin inhalation Inhaled intratracheal administration investigated Ivermectin kidney Lactose less limit limitation liver Local low dose lung Lungs mice Mild overcome pharmacokinetic pharmacokinetics plasma Protein Protein binding resolved respiratory tract Safety SARS-CoV-2 spleen spray Spray drying therapeutic Toxicity Treatment viral pathology was used [DOI] 10.1016/j.ijpharm.2022.121688 PMC 바로가기 [Article Type] Article
Dual targeting powder formulation of antiviral agent for customizable nasal and lung deposition profile through single intranasal administrationArticle Published on 2022-03-282023-07-01 Journal: International journal of pharmaceutics [Category] COVID19(2023년), SARS, [키워드] ACE2, angiotensin-converting enzyme 2 antiviral agent COVID-19 COVID19, Coronavirus Disease 2019 Dry powder aerosol DSC, differential scanning calorimetry EF, Emitted fraction FPF, Fine particle fraction HPBCD, 2-hydroxypropyl-β -cyclodextrin intranasal delivery MERS-CoV, Middle East respiratory syndrome coronavirus NF, Nasal fraction NGI, Next Generation Impactor pulmonary delivery RF, Residual fraction SARS-COV-2, severe acute respiratory syndrome coronavirus-2 SD, Spray drying SEM, scanning electron microscopy SFD, Spray freeze drying Spray drying Spray freeze drying SREBP, sterol regulatory element binding protein TBA, Tert-Butyl alcohol TF, Throat fraction TFN, Two-fluid nozzle TGA, Thermogravimetric analysis USN, Ultrasonic nozzle [DOI] 10.1016/j.ijpharm.2022.121704 PMC 바로가기 [Article Type] Article
Optimization of a dry powder inhaler of ciprofloxacin-loaded polymeric nanomicelles by spray drying processarticle Published on 2019-06-302024-09-01 Journal: Pharmaceutical Development and Technology [Category] 폐렴구균 감염증, [키워드] ciprofloxacin Dry powder inhaler nanoaggregate optimization polymeric nanomicelle Spray drying [Article Type] article
The effect of formulation on spray dried Sabin inactivated polio vaccinearticle Published on 2018-08-312024-09-01 Journal: European Journal of Pharmaceutics and Biopharmaceutics [Category] 폴리오, [키워드] Atomization stress and dry powder D-antigen recovery Polio vaccine Spray drying [Article Type] article
Inhalable dry powder formulations of siRNA and pH-responsive peptides with antiviral activity against H1N1 influenza virusArticle Published on 2015-03-022023-06-24 Journal: Molecular Pharmaceutics [Category] 신종인플루엔자, [키워드] Influenza pH-responsive peptide pulmonary delivery RNA interference Small interfering RNA Spray drying [DOI] 10.1021/mp500745v