Examination of Cardiac Activity with ECG Monitoring Using Heart Rate Variability MethodsArticle Published on 2024-04-292024-09-05 Journal: Diagnostics [Category] update2024, [키워드] 3D phase space attractor arrhythmia cardiac monitoring ECG HRV analysis mobile device Poincaré plot recurrence plot sensors statistical analysis Syncope [DOI] 10.3390/diagnostics14090926 PMC 바로가기 [Article Type] Article
Metabolomics meets systems immunologyReviews Published on 2023-03-142024-09-05 Journal: EMBO Reports [Category] update2024, [키워드] Computational biology immunology Infection metabolism metabolomics multiomics statistical analysis systems immunology [DOI] 10.15252/embr.202255747 PMC 바로가기 [Article Type] Reviews
A novel statistical method predicts mutability of the genomic segments of the SARS-CoV-2 virusResearch Article Published on 2022-12-132022-10-29 Journal: Qrb Discovery [Category] COVID-19, [키워드] affected antiviral drugs approach candidate coding regions codon conserved correlated correlation determine develop disease distribution effective epitope Frequency genomic identify immunogenic peptide large-scale analysis mutability offer overcome pandemic pathogenesis of SARS-CoV-2 predict predicted Protein SARS-CoV-2 SARS-CoV-2 virus SARS-CoV2 scientist sequence Seven spike glycoprotein statistical statistical analysis target the SARS-CoV-2 virus treatments for COVID-19 Vaccine viral genome viral mutation whole genome whole genome sequence Word Ranking [DOI] 10.1017/qrd.2021.13 PMC 바로가기 [Article Type] Research Article
Identification of the Hub Genes and the Signaling Pathways in Human iPSC-Cardiomyocytes Infected by SARS-CoV-2Article Published on 2022-12-012022-11-16 Journal: Biochemical Genetics [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] Analysis applied Bioinformatics analysis biological process Biomarker Brain caused component Cytoscape software database dataset DEGs differentially expressed gene direct infection down-regulated gene enrichment analysis function Gene Expression Omnibus gene expression profile Gene ontology Genes GEO GraphPad Prism software High-throughput sequencing hub genes Human Human iPSC-cardiomyocytes identification infected with SARS-CoV-2 intestine KEGG kidney Kyoto Ligand liver Lung injury mechanisms myocardial injury organ pathway Pathways PPI PPI network protein-protein interaction R software receptor Research respiratory respiratory symptom SARS-CoV-2 screened sequencing data signaling pathway single-stranded RNA virus statistical analysis statistically significant TNF signaling Type type I interferon up-regulated was obtained was performed website [DOI] 10.1007/s10528-022-10206-7 PMC 바로가기
Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene-environment associationsArticle Published on 2022-11-042022-11-16 Journal: Scientific Reports [Category] 유전자 메커니즘, [키워드] Abstract affecting articles association biological processe Cell comprehensive resource COVID-19 criteria curated database dataset develop diabetes differentially expressed gene dysregulated enriched biological processes environmental factor environmental factors Gene Expression Gene Expression Omnibus Genes Infection initial Interaction lung cancer pathway predict R package retrieved rheumatoid arthritis selected signature smoking statistical analysis statistically tested [DOI] 10.1038/s41598-022-21988-6 PMC 바로가기
Diffusion-Induced Ingress of Angiotensin-Converting Enzyme 2 into the Charge Conducting Path of a Pentacene Channel for Efficient Detection of SARS-CoV-2 in Saliva SamplesArticle Published on 2022-10-282022-11-15 Journal: ACS Sensors [Category] COVID19(2023년), SARS, 치료기술, [키워드] accelerate ACE2 angiotensin-converting enzyme 2 Angiotensin-converting enzyme 2 (ACE2) biosensor can be used channel charge Conducting correlation COVID-19 detection diagnostic test disease efficient false-negative field-effect transistor. gold standard growth handling highest integration Laboratory Large-scale testing less medium molecular Organic field-effect transistor path pathogen platform POC point-of-care Rapid receptor remote monitoring reported Saliva Sample SARS-CoV-2 sensitivity specimens Spread statistical analysis the disease the epidemic the SARS-CoV-2 virus the spike protein transfer Viral RNA viral titer virus [DOI] 10.1021/acssensors.2c01287 PMC 바로가기
Differential Infectivity of Original and Delta Variants of SARS-CoV-2 in Children Compared to AdultsArticle Published on 2022-10-262022-11-16 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 유전자 메커니즘, [키워드] acute respiratory syndrome Adults age aliquot B.1.617.2 Canada characteristic children circulating circulating SARS-CoV-2 variants coronavirus COVID-19 Culture cycle threshold Delta delta variant demographics determine dose driver implicated in viral Infection infectious titers infective Infectivity mechanism Mutation Nasopharyngeal swab nasopharyngeal swab sample original pediatric positive predominant provided RT-PCR SARS-CoV-2 SARS-CoV-2 RT-PCR screened statistical analysis susceptible TCID TCID50 TCID50. tissue Transmission variant variants of concern variety Viral RNA VoC [DOI] 10.1128/spectrum.00395-22 PMC 바로가기
Genetic variants determine intrafamilial variability of SARS-CoV-2 clinical outcomes in 19 Italian familiesArticle Published on 2022-10-132022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] acute respiratory syndrome addition Analysis association carried characterized clinical expression Clinical outcome clinical variability coronavirus COVID-19 determine disease genetic background genetic profile heterogeneity Host host response Immunity Infection Interaction involved Italian multifactorial occurred outcome performed Perspective phenotype positive protective effect rare variant risk SARS-CoV-2 shown SNPs statistical analysis statistically significant subject susceptibility the disease Transmission Transmission dynamics Vaccine Variability variant viral infection virus virus entry [DOI] 10.1371/journal.pone.0275988 PMC 바로가기
Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5Article Published on 2022-10-132022-11-15 Journal: Cell [Category] COVID19(2023년), SARS, 진단, [키워드] ACE2 binding alveolar epithelial cell BA.2 BA.2.12.1 BA.4 BA.5 bind Characteristics COVID-19 Culture effective experiment greater hamster Health human ACE2 immune immune evasion immune resistance Immunity Infection less omicron pathogenic pathogenicity provided replicate Reproduction number risk SARS-CoV-2 spike receptor-binding domain Spread statistical analysis Substitution suggested the SARS-CoV-2 Transmissibility [DOI] 10.1016/j.cell.2022.09.018 PMC 바로가기
The impact of crowd gatherings on the spread of COVID-19Research article Published on 2022-10-012022-10-05 Journal: Environmental research [Category] 변종, [키워드] addition Affect Characteristics collected COVID-19 COVID-19 pandemic crowd database dataset Epidemic epidemic model Epidemic prediction event events Factor Gathering events highest incidence indicated less occur Occurrence Outbreaks Patient reduced Simulation Spread spread of COVID-19 statistical analysis the disease the epidemic Transmission triggered were used [DOI] 10.1016/j.envres.2022.113604 [Article Type] Research article