Hypermethylation of the glutathione peroxidase 4 gene promoter is associated with the occurrence of immune tolerance phase in chronic hepatitis BResearch Published on 2024-03-212024-09-05 Journal: Virology Journal [Category] update2024, [키워드] Chronic Hepatitis B DNA methylation Glutathione peroxidase 4 oxidative stress STING [DOI] 10.1186/s12985-024-02346-6 PMC 바로가기 [Article Type] Research
Immunostimulation of Fibrous Nucleic Acid Nanoparticles Can be Modulated through Aptamer-Based Functional Moieties: Unveiling the Structure–Activity Relationship and Mechanistic Insightsarticle Published on 2024-02-122024-09-05 Journal: ACS Applied Materials & Interfaces [Category] update2024, [키워드] cGAS Cytokines DNA immunostimulation Nanoparticles NANPs RNA STING [DOI] 10.1021/acsami.3c17779 PMC 바로가기 [Article Type] article
Impaired STING Activation Due to a Variant in the E3 Ubiquitin Ligase AMFR in a Patient with Severe VZV Infection and Hemophagocytic Lymphohistiocytosis심각한 VZV 감염 및 혈구탐식 림프조직구증을 앓고 있는 환자에서 E3 유비퀴틴 리가제 AMFR의 변이에 의한 STING 활성화 손상Article Published on 2024-01-262024-08-16 Journal: Journal of Clinical Immunology [Category] 대상포진, [키워드] AMFR HLH interferon ISG STING ubiquitin ligase VZV.
At the Crossroads of the cGAS-cGAMP-STING Pathway and the DNA Damage Response: Implications for Cancer Progression and TreatmentReview Published on 2023-12-012024-09-05 Journal: Pharmaceuticals [Category] update2024, [키워드] BRCA Cancer cGAMP cGAS interferon signaling Metastasis Proton channel STING [DOI] 10.3390/ph16121675 PMC 바로가기 [Article Type] Review
STING agonist-derived LNP-mRNA vaccine enhances protective immunity against SARS-CoV-2Article Published on 2023-09-202024-09-05 Journal: Nano Letters [Category] update2024, [키워드] Lipid nanoparticles mRNA SARS-CoV-2 Spike protein STING Vaccine [DOI] 10.1021/acs.nanolett.2c04883 PMC 바로가기 [Article Type] Article
Beyond DNA sensing: expanding the role of cGAS/STING in immunity and diseasesarticle Published on 2023-06-242024-09-05 Journal: Archives of pharmacal research [Category] update2024, [키워드] Cancer cGAS DNA, immunity Inflammation STING [DOI] 10.1007/s12272-023-01452-3 PMC 바로가기 [Article Type] article
The Papain-Like Protease of Porcine Reproductive and Respiratory Syndrome Virus Impedes STING Translocation from the Endoplasmic Reticulum to the Golgi Apparatus by Deubiquitinating STIM1Virus-Cell Interactions Published on 2023-04-112024-09-05 Journal: Journal of virology [Category] update2024, [키워드] deubiquitinate NSP2 Papain-like protease PRRSV STIM1 STING [DOI] 10.1128/jvi.00188-23 PMC 바로가기 [Article Type] Virus-Cell Interactions
An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2Article Published on 2023-02-082023-07-11 Journal: Cell Host & Microbe [Category] COVID19(2023년), [키워드] AIM2 IL-1β IL-6 Inflammasome NLRP1 NLRP3 SARS-CoV-2 STING TLR2 [DOI] 10.1016/j.chom.2022.12.005 PMC 바로가기
Varicella-Zoster Virus ORF39 Transmembrane Protein Suppresses Interferon-Beta Promoter Activation by Interacting with STINGArticle Published on 2023-02-012023-05-31 Journal: Journal of microbiology (Seoul, Korea) [Category] 두창, 수두, 홍역, [키워드] interferon ORF39 STING VZV. [DOI] 10.1007/s12275-023-00019-7
Synthetic Stimulator of Interferon Genes (STING) Agonists Induce a Cytokine-Mediated Anti-Hepatitis B Virus Response in Nonparenchymal Liver CellsArticle Published on 2023-01-132023-06-11 Journal: ACS Infectious Diseases [Category] B형 간염, [키워드] antiviral immunity Chronic Hepatitis B cytokine HBV-persistent mouse model nonparenchymal liver cells. STING [DOI] 10.1021/acsinfecdis.2c00424