One size does not fit all: an application of stochastic modeling to estimating primary healthcare needs in Ethiopia at the sub-national level하나의 크기가 모든 것에 적합하지는 않습니다: 하위 국가 수준에서 에티오피아의 1차 의료 수요를 추정하기 위한 확률론적 모델링 적용Article Published on 2023-10-062024-07-29 Journal: BMC Health Services Research [Category] 말라리아, [키워드] Ethiopia human resources for health Monte Carlo PACE-HRH Primary Healthcare stochastic Sub-national workload [DOI] 10.1186/s12913-023-10061-1 PMC 바로가기
Wastewater and marine bioindicators surveillance to anticipate COVID-19 prevalence and to explore SARS-CoV-2 diversity by next generation sequencing: One-year studyCOVID-19 유행을 예측하고 차세대 염기서열 분석을 통해 SARS-CoV-2 다양성을 탐색하기 위한 폐수 및 해양 생물지표 감시: 1년 연구Article Published on 2022-08-102022-09-11 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 바이오마커, 변종, 치료기술, [키워드] a minor Analysis Biomarker Combination COVID-19 detect discharge eliminated Epidemiology Evolution Final Forecasting health system mathematical minor outbreak pandemic plant predict Predictive model Prevalence provided quantification RNA sampling SARS-CoV-2 SARS-CoV-2 sequencing SARS-CoV-2 surveillance Seawater Spain stochastic stochastic SIR model Surveillance the marine treated Treatment Viral Viral load virus virus variants was used wastewater Wastewater-based epidemiology water [DOI] 10.1016/j.scitotenv.2022.155140 PMC 바로가기 [Article Type] Article
A Hybrid Epidemic Model to Explore Stochasticity in COVID-19 DynamicsCOVID-19 역학에서 확률을 탐색하기 위한 하이브리드 전염병 모델Article Published on 2022-07-202022-09-11 Journal: Bulletin of Mathematical Biology [Category] COVID19(2023년), SARS, 치료기술, [키워드] adopted approaches Canada Clinical data confirmed case contributed COVID-19 COVID-19 outbreak COVID-19 pandemic death death rates determine differential equation disease disease transmission Dynamics e parameters Environmental variability Face masks hybrid Impact initiated Measures Model outbreak parameter Parameter estimation Probability public health Public health intervention Public health interventions reducing severity of COVID-19 shown silent Silent spreader social distancing Stage stochastic Stochastic models. subpopulations Symptom symptomatic Transmission transmission rate transmission rates USA Variability virus [DOI] 10.1007/s11538-022-01030-6 PMC 바로가기 [Article Type] Article
Discovery of new drug indications for COVID-19: A drug repurposing approachCOVID-19에 대한 신약 적응증의 발견: 약물 용도 변경 접근Article Published on 2022-05-242022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 신약개발, 진단, 치료제, [키워드] addition adopted Analysis anti-SARS-CoV-2 antiviral activity approach approved Baricitinib benefit binding energy calculated candidate drugs carried caused Cluster cluster analysis Clustering Combination Compound coronavirus demonstrated Dexamethasone docking result docking results docking study Doxorubicin drug drugs effective embedding Final generate generic drugs Health help in-silico In-vitro indication Interaction likelihood measure optics Ordering outbreak outlier performed Point PubChem public health Remdesivir Research Safety measures SARS-CoV-2 similarity stochastic Structure suggested Symptom Target genes therapy unique utility [DOI] 10.1371/journal.pone.0267095 PMC 바로가기 [Article Type] Article
An Ensemble Learning Model for COVID-19 Detection from Blood Test SamplesArticle Published on 2022-03-132022-11-16 Journal: Sensors (Basel, Switzerland) [Category] 치료기술, [키워드] Accuracy AdaBoost approach AUC Blood blood tests Classifier clinician CNN conducted COVID-19 COVID-19 disease current dataset datasets decision deep learning descent detection detection system develop diagnose Diagnosis diagnostic Diagnostic model diagnostics Discriminant effective Ensemble learning experiment feature forest Gradient Laboratory learning limitation machine learning algorithm Model Naïve Bayes outperform Passive perceptron polymerase chain Regression Research reverse transcription ridge RT-PCR Sample San Raffaele Hospital small data. stochastic support vector machine Test tree virus [DOI] 10.3390/s22062224 PMC 바로가기
A novel adaptive momentum method for medical image classification using convolutional neural networkConvolutional Neural Network를 사용하여 의료 이미지 분류를위한 새로운 적응 모멘텀 방법Research Published on 2022-03-012022-09-01 Journal: BMC Medical Imaging [Category] Fulltext, MERS, SARS, 진단, [키워드] Accuracy ADAM adaptive Adaptive momentum methods Algorithm Applying Backpropagation algorithm changes chest X-ray CNN CNNs complex constant Convolutional neural network Convolutional neural networks COVID-19 CT scan dataset Diagnosis epoch high accuracy highest IMPROVE investigated lowest medical diagnosis Medical image classification momentum NIH Nonconvex optimization outcome reducing REMBRANDT Result stochastic tested X-ray [DOI] 10.1186/s12880-022-00755-z PMC 바로가기 [Article Type] Research
Sensitivity of SARS-CoV-2 Life Cycle to IFN Effects and ACE2 Binding Unveiled with a Stochastic ModelArticle Published on 2022-02-152022-10-28 Journal: Viruses [Category] COVID-19, COVID19(2023년), Fulltext, SARS, [키워드] ACE2 ACE2 binding antiviral treatments binding caused Cell chain Characteristics component cycle deterministic model Effect fluctuation help IFN Infection infection process inhibitory effect life Markov Markov chain Monte Carlo method mathematical mathematical model Model parameter Probability progeny SARS-CoV-2 sensitivity analysis Single Cell statistical stochastic stochastic processes the ACE2 receptor the SARS-CoV-2 to define turn Type I IFN type I interferon (IFN) Variation virus dynamics [DOI] 10.3390/v14020403 PMC 바로가기 [Article Type] Article
Global Industrial Development: Insights From the Distribution Dynamics Approach for the Post Covid EraPublic Health Published on 2021-11-232022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] Analysis average carried convergence country COVID-19 distribution distribution dynamics Dynamics Effect Effectiveness feasibility global inequality group Industrial industrial development insight National North significantly South spread of COVID-19 stochastic understanding [DOI] 10.3389/fpubh.2021.792947 PMC 바로가기 [Article Type] Public Health
Transcriptional Profiling and Machine Learning Unveil a Concordant Biosignature of Type I Interferon-Inducible Host Response Across Nasal Swab and Pulmonary Tissue for COVID-19 Diagnosis전사 프로파일링 및 기계 학습, COVID-19 진단을 위한 비강 면봉 및 폐 조직 전반에 걸쳐 I형 인터페론 유도성 숙주 반응의 일치하는 생체특징 공개Immunology Published on 2021-11-222022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] adjusted adopted Analysis approach biosignature BST2 caused complementary computational analysis concordant conserved COVID-19 COVID-19 diagnosis data interpretation dataset Diagnosis Diagnostic method embedding Factor false-negative Genes geometric global pandemic GSE147507 heterogeneous high mortality homological Host host response IFIT1 IFIT2 IFIT3 IFITM1 IFN-I IFN-I signaling infection control Interferome interferon involved ISG15 Limited lung tissue machine learning morbidity MX1 MX2 nasal swab NCBI-GEO network OAS1 OAS2 OAS3 OASL objective other respiratory infections outcome Profiling pulmonary respiratory respiratory infections response Result retrieved RNA-seq data RNA-sequencing RSAD2 RT-PCR SARS-CoV-2 SARS-CoV-2 virus sequencing data severity of COVID-19 similarity Stat1 stochastic stratified transcriptional transcriptional level transcriptomics Type type I interferon virus was used WGCNA [DOI] 10.3389/fimmu.2021.733171 PMC 바로가기 [Article Type] Immunology
Stochastic social behavior coupled to COVID-19 dynamics leads to waves, plateaus, and an endemic stateResearch Article Published on 2021-11-082022-10-31 Journal: eLife [Category] COVID-19, MERS, SARS, [키워드] assumed consequence COVID-19 Endemic endemic state Epidemic epidemic dynamics Epidemics epidemiological feature herd immunity heterogeneity provide Spread stochastic suppressed the epidemic Variation viruses while [DOI] 10.7554/eLife.68341 PMC 바로가기 [Article Type] Research Article