Prophylaxis in healthcare workers during a pandemic: a model for a multi-centre international randomised controlled trial using Bayesian analysesRandomized Controlled Trial Published on 2022-06-272022-10-05 Journal: Trials [Category] COVID19(2023년), SARS, 임상, [키워드] acid acquisition acute respiratory syndrome adaptive Admission Analysis Bayesian Bayesian analysis Bayesian method coronavirus Coronavirus disease 2019 COVID-19 COVID-19 case determine Effect effective Efficacy expected fixed Follow-up futility greater had no hazard ratio HCQ HCW healthcare worker hospitalisation Hydroxychloroquine imperative Infection intensive care International Intervention Ireland less log mechanical ventilation Mortality multicentre New occur occurred Open-label outcome pandemic Pandemics parallel-group participant Pathogens posterior probability Pragmatic primary endpoint proceed Prophylactic Prophylaxis randomised randomised controlled trial RCT recruitment reducing reduction in risk Sample size SARS-CoV-2 SARS-COV-2 infection secondary shown Stopping Treatment Trial Trial registration variable [DOI] 10.1186/s13063-022-06402-w PMC 바로가기 [Article Type] Randomized Controlled Trial
Impact of Physical Activity Differences Due to COVID-19 Pandemic Lockdown on Non-Alcoholic Fatty Liver Parameters in Adults with Metabolic Syndrome대사 증후군이 있는 성인의 비알코올성 지방간 매개변수에 대한 COVID-19 유행성 폐쇄로 인한 신체 활동 차이의 영향Article Published on 2022-06-082022-09-11 Journal: Nutrients [Category] 임상, [키워드] activity affected Analysis blood collection Characteristics cholesterol COVID-19 COVID-19 lockdown COVID-19 pandemic decrease difference disease Efficiency Fatty liver fatty liver disease fitness functional group groups HDL-cholesterol healthy Impact IMPROVE inactive intensity lockdown longitudinal magnetic resonance imaging Mediterranean diet Mediterranean lifestyle medium metabolic metabolic syndrome moderate motivation MRI NAFLD Non-alcoholic fatty liver disease parallel-group parameter participant Patient per day physical activity progression questionnaire randomized trial Stopping syndrome were assessed worsening [DOI] 10.3390/nu14122370 PMC 바로가기 [Article Type] Article
Motor and respiratory decline in patients with late onset Pompe disease after cessation of enzyme replacement therapy during COVID-19 pandemicArticle Published on 2022-04-012023-07-07 Journal: European journal of neurology [Category] COVID19(2023년), [키워드] alglucosidase alfa enzyme therapy Stopping Suspension treatment management. [DOI] 10.1111/ene.15222
Professionals’ Digital Training for Child Maltreatment Prevention in the COVID-19 Era: A Pan-European ModelArticle Published on 2022-01-132022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS, [키워드] activities approach Child child maltreatment children COVID-19 COVID-19 pandemic Critical Digital Digital health disrupt e-learning European evaluated examined Factor feature Interaction interactive module Model Multidisciplinary pandemic Participants platform prevention professional professionals reduce reduced Seven significantly Stopping training [DOI] 10.3390/ijerph19020885 PMC 바로가기 [Article Type] Article
Psychological Impact of the COVID-19 Pandemic on Out-of-Hospital Health Professionals: A Living Systematic ReviewReview Published on 2021-11-272022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] affected Anxiety being clinical history Cochrane Library confirmed case Contact COVID-19 COVID-19 pandemic database Defense Depression Depressive symptoms English Evidence Factor French greater group Health professionals IBECS identify illness Impact Infection Italian LILACS mental health original Out-of-hospital pandemic Patient professional Research review risk Self-efficacy Spanish Stopping Stress systematic review thought was selected Web of Science [DOI] 10.3390/jcm10235578 PMC 바로가기 [Article Type] Review
Update on Intravenous Immunoglobulin in Neurology: Modulating Neuro-autoimmunity, Evolving Factors on Efficacy and Dosing and Challenges on Stopping Chronic IVIg TherapyCurrent Perspectives Published on 2021-11-112022-10-30 Journal: Neurotherapeutics : the journal of the American So [Category] Coronavirus, MERS, SARS, [키워드] Activation addressed affecting Anti-inflammatory effects anti-SARS-CoV-2 antibodies antibody antigenic peptides approved autoantibodies Autoimmune challenge chronic complement conditions conserved cross-react Cytokines Dosing Effect effective Efficacy Encephalitis epilepsy Evidence exhibit Express Factor fatigue FcγRIIb genes encoding Genetic healthy donors Humoral immunity IgG IgG1 Immunomodulation by IVIg Inflammatory mediators infused Initiating and stopping IVIg Intravenous immunoglobulin isotype IVIG IVIg and IgG4 neuro-autoimmunities MMN neurological Neurological disorders neurological sign neuronal pathogenic autoantibody Patient polymorphism positive Protein Randomized controlled trials recent receptors sera stability Stopping Symptom therapy Treatment weakness worsening [DOI] 10.1007/s13311-021-01108-4 PMC 바로가기 [Article Type] Current Perspectives
Stopping the COVID-19 pandemic in dental offices: A review of SARS-CoV-2 transmission and cross-infection prevention치과 진료소에서 COVID-19 전염병 중지: SARS-CoV-2 전염 및 교차 감염 예방에 대한 검토Review Published on 2021-11-012022-09-11 Journal: Experimental Biology and Medicine [Category] SARS, 치료기술, [키워드] Anxiety center change changed costly COVID-19 COVID-19 pandemic COVID-19 patients COVID-19 testing COVID-19 vaccination cross-contamination Cross-infection dental dentist dentistry dentists detect disease disease control Effect effective Guidance Health help identify infection control maintain no symptoms pandemic pathway Patient patients peer-reviewed people with COVID-19 Personal protective equipment Prevent PRISMA protocols public health Rapid test SARS-CoV-2 SARS-CoV-2 transmission social distancing spread of COVID-19 Stopping time-consuming Transmission Treatment treatment protocols Triage triage dental treatments. vaccinate vulnerable patients widespread [DOI] 10.1177/15353702211034164 PMC 바로가기 [Article Type] Review
A single-center report of COVID-19 disease course and management in liver transplanted pediatric patients간이식 소아 환자의 COVID-19 질병 경과 및 관리에 대한 단일 센터 보고서Article Published on 2021-11-012022-09-11 Journal: Pediatric transplantation [Category] SARS, 치료기술, [키워드] absence Allograft Anakinra anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody Antibiotic therapy antibody children Clinical and laboratory data collected COVID-19 COVID-19 diagnosis COVID-19 disease course COVID-19 symptom develop diagnosed disease severity electronic patient record Electronic patient records Everolimus Favipiravir Hyperactivation IL-6 immune system Immunocompromised Immunocompromised patient Immunocompromised patients Immunosuppression increased risk IVIG laboratory data liver liver transplant Liver transplantation lymphopenia management median median age MMF mounted Non-invasive not affect one patient Oxygenation Patient patients PCR positive PCR test Pediatric patient probable COVID-19 retained SARS-CoV-2 serum Serum IL-6 severe COVID-19 symptoms single-center solid organ Stopping Support survival tacrolimus therapy Treatment treatment guideline treatment guidelines virtue were used with COVID-19 written consent X-ray [DOI] 10.1111/petr.14061 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Vaccination in Children and Adolescents—A Joint Statement of the European Academy of Paediatrics and the European Confederation for Primary Care PaediatriciansPediatrics Published on 2021-08-232022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] Academy adolescents Adults age appear benefit children conducted consequence COVID-19 COVID-19 pandemic effective ethical concerns European infectious diseases prevention International National paediatrics pandemic pediatric Pediatrician recommendation Safe SARS-CoV-2 Stopping vaccination Vaccines [DOI] 10.3389/fped.2021.721257 PMC 바로가기 [Article Type] Pediatrics
Interplay between interleukin-6 signaling and the vascular endothelium in cytokine storms사이토카인 폭풍에서 인터루킨-6 신호와 혈관 내피 사이의 상호작용Review Published on 2021-07-122022-09-12 Journal: Experimental & Molecular Medicine [Category] SARS, 진단, [키워드] abnormal coagulation activate Acute inflammation Affect anti-IL-6 receptor antibody Arthritis block blocking CAR-T cell therapy Cell characterized chemokine chimeric antigen receptor chronic inflammatory disease coagulation cascade coronavirus disease COVID-19 cytokine Cytokine storm Cytokine storms Defense demonstrated disease dysregulation Effect Evidence healthy help highlight Host humanized IL-6 IL-6 receptor IL-6 signaling immune response implicated indicate Infection inflammatory conditions Inflammatory response interleukin-6 Interleukins Japan management Pathogenesis recent receptors rheumatoid arthritis Sepsis shown Signaling signaling molecule spiral Stopping suppress systemic inflammation T-cell therapeutic potential therapeutic strategy tissue injury Tocilizumab Treatment university vascular endothelial cells Vascular endothelium vascular leakage [DOI] 10.1038/s12276-021-00649-0 PMC 바로가기 [Article Type] Review