The pipeline for drugs for control and elimination of neglected tropical diseases: 2. Oral anti-infective drugs and drug combinations for off-label usearticle Published on 2023-10-312024-09-05 Journal: Parasites & Vectors [Category] update2024, [키워드] Acedapsone albendazole amoxicillin Artemether artemisinins Arterolane artesunate Azithromycin azoles Balapiravir celgosivir Chloroquine clarithromycin Clavulanate CURE ID dapsone Diethylcarbamazine disulfiram doxycycline Drug reprofiling Drug repurposing fluconazole Imatinib Isavuconazonium itraconazole Ivermectin ketoconazole Levamisole Lumefantrine Mebendazole mefloquine Moxidectin moxifloxacin Neglected topical diseases nitazoxanide off-label use Oxamniquine Oxantel Piperaquine Posaconazole Praziquantel Pyrantel pamoate ravuconazole ribavirin rifampicin Rifapentine Sparfloxacin streptomycin Tribendimidine UV-4B [DOI] 10.1186/s13071-023-05909-8 PMC 바로가기 [Article Type] article
Aminoglycosides as potential inhibitors of SARS-CoV-2 main protease: an in silico drug repurposing study on FDA-approved antiviral and anti-infection agentsSARS-CoV-2 주요 프로테아제의 잠재적 억제제로서의 아미노글리코사이드: FDA 승인 항바이러스제 및 항감염제에 대한 실리코 약물 용도 변경 연구Article Published on 2021-05-012022-08-31 Journal: Journal of infection and public health [Category] MERS, SARS, 신약개발, 치료제, [키워드] Amikacin Aminoglycoside Aminoglycosides anti-infection Antibiotics Antiviral approach binding cleaving clinical trials clinically complex COVID-19 docking Docking and simulation drug drug candidate drugs evaluate exhibited followed by free energy Free energy calculation Free energy calculations help hydrogen hydrogen bonds in silico in vitro in vivo inhibitor inhibitors of SARS-CoV-2 interactions iodixanol lead lowest M pro MD simulation MD simulations molecular molecular docking molecular dynamics Neomycin overcome pandemic protease required residues rutin salt salt bridges SARS-CoV-2 screened Simulation Spread streptomycin suggested tobramycin troxerutin van der Waal van der Waals interactions Virtual screening [DOI] 10.1016/j.jiph.2021.01.016 PMC 바로가기 [Article Type] Article
In silico screening of known small molecules to bind ACE2 specific RBD on Spike glycoprotein of SARS-CoV-2 for repurposing against COVID-19Research Article Published on 2020-07-012022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] ACE2 anti-viral activity approved clinically computer-aided drug design coronavirus COVID-19 docking study drug drugs effective Efficacy glycoprotein hACE2 receptor host cell Human in silico inhibitory Interaction interfere Intervention MD simulation molecular morbidity and mortality pandemic Pathogen host interaction pathogenic Protein RBD reported repurposing Result safety profile SARS-CoV-2 SARS-CoV-2-S SARS-CoV-2-Spike Glycoprotein screened selected small molecule Small molecules spike spike glycoprotein streptomycin treat treating COVID-19 viral cellular entry [DOI] 10.12688/f1000research.24143.1 PMC 바로가기 [Article Type] Research Article
Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase from Salmonella enterica살모넬라 엔테리카에서 유래한 이중 특이성 아미노글리코사이드 아데닐릴트랜스퍼라제 AadA의 구조적 메커니즘Article Published on 2018-07-202024-07-29 Journal: Brain stimulation [Category] 살모넬라증, [키워드] Antibiotic resistance Antibiotics ATP enzyme mechanism enzyme structure spectinomycin streptomycin X-ray crystallography [DOI] 10.1074/jbc.RA118.003989 PMC 바로가기
Effects of antimicrobial use in agricultural animals on drug-resistant foodborne salmonellosis in humans: A systematic literature review농업 동물에서 항균제 사용이 인간의 약물 내성 식품 매개 살모넬라증에 미치는 영향: 체계적인 문헌 검토Article Published on 2017-02-112024-08-21 Journal: Critical Reviews in Food Science and Nutrition [Category] 살모넬라증, [키워드] farm-to-fork food safety meat streptomycin Tetracycline
A new subclass of intrinsic aminoglycoside nucleotidyltransferases, ANT(3″)-II, is horizontally transferred among Acinetobacter spp. by homologous recombination고유 아미노글리코사이드 뉴클레오티딜트랜스퍼라제의 새로운 서브클래스인 ANT(3")-II는 상동 재조합에 의해 Acinetobacter spp. 사이에서 수평으로 전달됩니다.Research Article Published on 2017-02-022022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] Acinetobacter Aminoglycoside Antibiotic resistance antibiotic resistance gene Author Bacterial capture clades conserved demonstrated disseminate dissemination Genes genes encoding genomic genomic region genus Homologous recombination hotspot insertion sequence insertion sequences intrinsic investigated lead mechanism MOST natural resistance Pathogens pathway Plasmid plasmids populations Prevalence provided resistance gene resistance genes species spectinomycin Spread streptomycin transferred variant [DOI] 10.1371/journal.pgen.1006602 PMC 바로가기 [Article Type] Research Article
Using whole-genome sequencing to determine appropriate streptomycin epidemiological cutoffs forSalmonellaandEscherichia coli전체 유전체 시퀀싱을 사용하여 살모넬라 및 대장균에 대한 적절한 스트렙토마이신 역학 기준값을 결정하기journal-article Published on 2016-02-012024-08-20 Journal: FEMS Microbiology Letters [Category] 살모넬라증, [키워드] E. coli genotyping resistance Salmonella streptomycin whole-genome sequencing [DOI] 10.1093/femsle/fnw009 [Article Type] journal-article
Streptomycin-lidocaine injections for the treatment of postherpetic neuralgia: Report of three cases with literature reviewCase Report Published on 2013-09-012024-09-04 Journal: European Journal of Dentistry [Category] 대상포진, [키워드] Neuralgic pain peripheral injections Postherpetic neuralgia streptomycin [DOI] 10.4103/1305-7456.119086 PMC 바로가기 [Article Type] Case Report