The associations between COVID-19 vaccination and psychological disorders among healthcare workers in ChinaArticle Published on 2022-12-012022-11-16 Journal: Journal of affective disorders [Category] COVID19(2023년), SARS, 치료기술, [키워드] adverse event analyzed Anxiety association caused China collected conducted Coverage COVID-19 COVID-19 vaccination COVID-19 vaccine cross-sectional DASS-21 Depression Factor healthcare healthcare worker incidence Logistic regression mean score nonparametric test participant Prevalence Psychological psychological disorder Psychological state Public Health Agency scored significantly higher significantly lower Sociodemographic characteristics Stress Stress Scale subgroups suffered the mean vaccination vaccination rate Vaccines [DOI] 10.1016/j.jad.2022.08.080 PMC 바로가기
Does timing matter on tocilizumab administration? Clinical, analytical and radiological outcomes in COVID-19Article Published on 2022-11-012022-11-15 Journal: European Journal of Hospital Pharmacy [Category] SARS, 진단, [키워드] 30-Day mortality Administered administration adverse event adverse events analysed Biomarker C-reactive protein clinical Clinical improvement cohorts of patient comparable complementary Complementary therapies coronavirus disease COVID-19 Critical Critical care decrease Efficacy epidemiologically group hospitalised Hypothesis inflammatory parameters knowledge lactate dehydrogenase medication Mortality onset of symptom outcome Patient patients with COVID-19 pharmacological treatment Pneumonia Primary outcome pulmonary medicine Quotient radiological radiological improvement radiology randomised controlled trial reductions in SaO_{2} secondary Severe COVID-19 pneumonia statistically significant difference subgroup subgroups the timing therapy Tocilizumab tocilizumab administration two group were recorded while [DOI] 10.1136/ejhpharm-2020-002669 PMC 바로가기
A Multicenter Clinical Diagnostic Accuracy Study of SureStatus, an Affordable, WHO Emergency Use-Listed, Rapid, Point-Of-Care Antigen-Detecting Diagnostic Test for SARS-CoV-2Article Published on 2022-10-262022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] 95% confidence interval access Accuracy acute respiratory syndrome Ag-RDT Ag-RDTs Analysis Antigen-detecting rapid diagnostic tests B.1.1.7 characterized circulating clinical Combination complement coronavirus COVID-19 Critical cycle threshold demonstrated diagnostic Emergency Emergency use evaluated facilitate Factor Germany gold standard highlight independent India multicenter nasopharyngeal Oropharyngeal overcome participant Participants performance performed point-of-care positive post-symptom onset questionnaire raised Rapid Rapid diagnostic test recruited resources reverse transcription-PCR RT-PCR RT-PCR testing SARS-CoV-2 SARS-COV-2 infection sensitivity specificity subgroup subgroups Support SUS Swab symptom duration symptom onset Symptoms Test Transmission variant Viral load was used WHO widespread World Health Organization [DOI] 10.1128/spectrum.01229-22 PMC 바로가기
Head-to-head comparison of the accuracy of saliva and nasal rapid antigen SARS-CoV-2 self-testing: cross-sectional studyArticle Published on 2022-10-242022-11-15 Journal: BMC Medicine [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Accuracy Ag-RDT Ag-RDTs analyses Antigen antigen detection antigen test asymptomatic individual COVID-19 cross-sectional cross-sectional study cut-off diagnostic Diagnostic accuracy diagnostic test Diagnostic test accuracy E-gene General population individual Interpretation molecular molecular test MOST nasal Nasal test Negative predictive value participant Participants positive Positive predictive value presenting public health Rapid rapid antigen detection test Roche Diagnostics Saliva saliva test SARS-CoV-2 SARS-CoV-2 detection SARS-COV-2 infection SARS-CoV-2 testing SD Biosensor sensitivity subgroups Symptom symptomatic and asymptomatic Viral load [DOI] 10.1186/s12916-022-02603-x PMC 바로가기
Immunogenicity and safety of the booster BNT162b2 vaccine in patients with axial spondyloarthritis treated with biological disease-modifying drugsArticle Published on 2022-09-232022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome adverse event antibody concentration axial spondyloarthritis biological disease-modifying drug BNT162b2 BNT162b2 vaccine booster booster doses booster vaccination clinical questionnaire Cohort cohorts comparable coronavirus disease Coronavirus-2 COVID-19 enrolled evaluated Evidence flow cytometric General population healthy control humoral IL-17 immune response Immune-mediated inflammatory disease immunogenicity individuals inhibitor inhibitors intracellular cytokine investigated male no difference outcome Patient patients patients treated peptide-based persistence prospective observational study Responder Safety SARS-CoV-2 Specific spondyloarthritis subgroups T-cell T-cell immune response T-cell Response therapy TNFα treated tumor necrosis factor-alpha vaccination virus-neutralizing antibody were assessed [DOI] 10.3389/fimmu.2022.1010808 PMC 바로가기
Safety and tolerability of SARS-Cov-2 vaccination in patients with myasthenia gravis: A multicenter experience중증 근무력증 환자에서 SARS-Cov-2 백신 접종의 안전성 및 내약성: 다기관 경험Multicenter Study Published on 2022-08-012022-09-12 Journal: European journal of neurology [Category] COVID19(2023년), SARS, 진단, [키워드] Administered Clinical characteristics collected Complication contributed COVID-19 pandemic Diagnosis dose eight enrolled Fever Frequency high risk higher risk information lack large cohort local pain mRNA COVID-19 vaccines multicenter myasthenia gravis offered Patient patients reported Safety SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine serological severe COVID-19 Side effect significantly higher Spontaneous subgroups subject Support Symptom Tolerability tyrosine vaccination Vaccine vaccine dose Vaccine hesitancy were assessed worsened worsening [DOI] 10.1111/ene.15348 PMC 바로가기 [Article Type] Multicenter Study
Geographic, Occupational, and Sociodemographic Variations in Uptake of COVID-19 Booster Doses Among Fully Vaccinated US Adults, December 1, 2021, to January 10, 2022Article Published on 2022-08-012022-11-16 Journal: JAMA Network Open [Category] 변종, [키워드] 95% CI Adults age Analysis Asian booster dose Booster vaccine calculated Care census children conducted Coverage COVID-19 COVID-19 vaccine COVID-19 vaccines cross-sectional survey defined diagnosis of COVID-19 dose effort enrolled estimate female Geographic Health highest hospital household Immunity IMPROVE individual janssen less likelihood Medicaid Medicare multivariable National occupational Older outcome percentages pharmacies Poisson regression model Population Prevalence prevalence ratio proportion receipt receiving reported selected Social service Sociodemographic subgroups survey uptake used data Vaccine variants Variation Vermont waning immunity [DOI] 10.1001/jamanetworkopen.2022.27680 PMC 바로가기
Stress hyperglycemia ratio, rather than admission blood glucose, predicts in-hospital mortality and adverse outcomes in moderate-to severe COVID-19 patients, irrespective of pre-existing glycemic statusResearch article Published on 2022-08-012022-10-05 Journal: Diabetes research and clinical practice [Category] 바이오마커, 진단, [키워드] ABG Admission adverse outcome AUROC blood glucose COVID-19 COVID-19 infection COVID-19 patient COVID-19 severity diabete died glycemic hyperglycemia ICU identify in-hospital mortality incidence independent Logistic regression mechanical ventilation median moderate-severe Mortality multiple organ dysfunction outcome outcomes Patient patients with COVID-19 pre-diabete predict predictor Prevalence Primary outcome Result secondary outcome severe COVID-19 patients significantly higher Stress hyperglycemia Stress hyperglycemia ratio subgroup analysis subgroups syndrome tested Type was done [DOI] 10.1016/j.diabres.2022.109974 [Article Type] Research article
The impact of COVID-19 pandemic on individuals at clinical high-risk for psychosis: Evidence from eye-tracking measuresResearch article Published on 2022-08-012022-10-05 Journal: Progress in neuro-psychopharmacology & biological [Category] 바이오마커, 임상, [키워드] abnormality Accuracy amplitude Biomarker caused Characteristics checklist Clinical high-risk for psychosis Clinical symptoms COVID-19 COVID-19 pandemic distress DSM-5 Effect Evidence eye Eye movement fixation healthy healthy control high risk Impact individual individuals information investigated measure Mental disorder negatively affected Pandemics participant Participants Perceived Stress Scale physiological post-traumatic provide PSS-10 Psychological distress PTSD reported saccade scale severity significantly significantly higher stability stratified Stress subgroups suggested Symptom the mean total score were assessed were measured [DOI] 10.1016/j.pnpbp.2022.110578 [Article Type] Research article
Immunogenicity and safety of booster dose of S-268019-b or BNT162b2 in Japanese participants: An interim report of phase 2/3, randomized, observer-blinded, noninferiority study일본 참가자의 S-268019-b 또는 BNT162b2 추가 용량의 면역원성과 안전성: 2/3상, 무작위, 관찰자 맹검, 비열등성 연구의 중간 보고서Clinical Trial Published on 2022-07-302022-09-11 Journal: Vaccine [Category] MERS, 변종, 임상, 진단, [키워드] 95% CI analyzed Anti-spike antibodies BNT162b2 booster booster dose Booster vaccine clinical clinical trial co-primary endpoint co-primary endpoints COVID-19 Delta elicited fatigue Fever geometric mean geometric mean titer GMT GMT ratio immunization immunogenicity Immunoglobulin Immunoglobulin G injection Injection-site pain Interim report Interim result interim results Japanese Live virus MOST myalgia neutralization test Neutralizing antibodies neutralizing antibody observer observer-blinded omicron P-value participant phase 2/3 produced pseudovirus Randomized reactogenicity recombinant Recombinant spike protein regimen reported robust Safe SARS-CoV-2 SARS-COV-2 infection Serious Adverse Event Serious Adverse Events Spike protein subgroups T-cell Response Vaccine variant [DOI] 10.1016/j.vaccine.2022.06.032 PMC 바로가기 [Article Type] Clinical Trial