Inhibitory effects of fucoidan from Laminaria japonica against some pathogenic bacteria and SARS-CoV-2 depend on its large molecular weightArticle Published on 2023-02-282023-07-11 Journal: International journal of biological macromolecules [Category] COVID19(2023년), [키워드] Foodborne pathogen Photocatalytic degradation sulfated polysaccharide virus [DOI] 10.1016/j.ijbiomac.2022.12.307 PMC 바로가기
An insight to the therapeutic potential of algae-derived sulfated polysaccharides and polyunsaturated fatty acids: Focusing on the COVID-19Review article Published on 2022-06-012022-10-05 Journal: International journal of biological macromolecules [Category] 변종, 치료제, [키워드] addition affected Algae candidate Compound coronavirus COVID-19 COVID-19 case Critical Effectiveness fatty Fatty acid Focusing Gut gut microbiome Health immune regulation immune system immunomodulatory activities immunomodulatory property Infection infections intestine Microbiome microbiota modulate modulating modulation Mutation nutritional intervention other organ pandemic Polyunsaturated Polyunsaturated fatty acids Prevent produced Research resources response sulfated polysaccharide sulfated polysaccharides the vaccine therapeutic therapeutic potential these compound Treatment Vaccine viral infections virus virus pathogenesis [DOI] 10.1016/j.ijbiomac.2022.03.063 [Article Type] Review article
Antiviral Activities of Algal-Based Sulfated Polysaccharides조류계 황산다당류의 항바이러스 활성Review Published on 2022-02-092022-09-10 Journal: Molecules [Category] COVID19(2023년), MERS, SARS, 변종, 치료제, [키워드] activity Alpha Antiviral antiviral agent Antiviral agents Beta carrageenan COVID-19 pandemic Culture Delta effective Efficacy feature Gamma highlight human coronavirus include Isolation macro macroalgae marine plants microalgae nasal Nasal spray offer omicron Omicron variants patients plants Probability provide Safe social distancing sulfated polysaccharide sulfated polysaccharides Toxicity Vaccine development variants of SARS-CoV-2 viral disease [DOI] 10.3390/molecules27041178 PMC 바로가기 [Article Type] Review
Antiviral Strategies Using Natural Source-Derived Sulfated Polysaccharides in the Light of the COVID-19 Pandemic and Major Human Pathogenic VirusesCOVID-19 Pandemic 및 주요 인간 병원성 바이러스에 비추어 천연 소스 유래 황산화 다당류를 사용한 항 바이러스 전략Review Published on 2021-12-242022-09-10 Journal: Viruses [Category] SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 antiviral activities and mechanisms antiviral activity Antiviral agents antiviral drugs antiviral efficacy antiviral potency Characteristics clinical settings contributing to coronavirus COVID-19 cytotoxicity drug drug structure-activity relationship emerging viral infections focus fraction heparin mimetics host cell Human in viral in vivo studies Infection investigated involved LIGHT Major major human pathogenic viruses majority many case many cases methodology molecular molecular mechanism molecular mechanisms molecules natural outbreak pathogenic virus Pathways polysaccharide profile Research respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus Strategy sulfated sulfated polysaccharide sulfated polysaccharides susceptible susceptible host treat variety Viral viral infection viral infections virus entry as a target viruses [DOI] 10.3390/v14010035 PMC 바로가기 [Article Type] Review
Iota-Carrageenan Inhibits Replication of SARS-CoV-2 and the Respective Variants of Concern Alpha, Beta, Gamma and DeltaIota-Carrageenan은 SARS-CoV-2 및 우려되는 알파, 베타, 감마 및 델타의 각 변종 복제를 억제합니다Article Published on 2021-12-082022-09-10 Journal: International Journal of Molecular Sciences [Category] SARS, 변종, 치료제, [키워드] age Alpha antiviral activity Antiviral effect Beta Calu Calu-3 can not carrageenan carrageenan types Carrageenans comparable concern contribute coronavirus COVID-19 COVID-19 pandemic Defense Delta effective exhibit Gamma human lung cell human lung cells independent independent of infect Infection inhibit investigated Iota iota-carrageenan kappa-carrageenan lack Lambda lambda-carrageenan lentivirus nasal Particle Prophylaxis pseudotyped pseudotyping public health threat reduce SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections SARS-CoV-2 spike Spread SSPL sulfated polymer sulfated polysaccharide sulfated polysaccharides supply the SARS-CoV-2 TMPRSS2 transgenic transmission of SARS-CoV-2 transmitted Treatment vaccination Vaccine Vaccine-induced immunity variants variants of concern Viral Viral transmission virulent virus variants VoC VOCs Wuhan [DOI] 10.3390/ijms222413202 PMC 바로가기 [Article Type] Article
Potential Antiviral Properties of Industrially Important Marine Algal Polysaccharides and Their Significance in Fighting a Future Viral PandemicReview Published on 2021-09-132022-10-28 Journal: Viruses [Category] COVID-19, [키워드] activities algal polysaccharides Anticoagulant Antioxidative Antiviral antiviral medicines Carrageenans exhibited Fighting Future Health immunomodulating Infection inhibitory effect investigated marine algae mechanism of action Medicines over pandemic Pandemics polysaccharide Potential property SARS-CoV-2 Significance Stage sulfated polysaccharide sulfated polysaccharides therapeutic potential virus [DOI] 10.3390/v13091817 PMC 바로가기 [Article Type] Review
Marine Sulfated Polysaccharides as Promising Antiviral Agents: A Comprehensive Report and Modeling Study Focusing on SARS CoV-2Article Published on 2021-07-222022-10-30 Journal: Marine Drugs [Category] COVID-19, SARS, [키워드] ACE2 acting acute respiratory syndrome affecting angiotensin-converting enzyme-2 Antiviral antiviral activity Antiviral effect articles binding binding site candidate chondroitin Comprehensive Coronavirus-2 death docking Drug discovery Efficacy effort examined exhibited experiment FIVE Focusing Infection inhibitors Interaction investigated modeling molecular docking molecular dynamic simulations Novel coronavirus Protective RBD report reported Research S-protein SARS CoV-2 SARS-CoV-2 Spike protein sulfated sulfated polysaccharide sulfated polysaccharides the receptor-binding domain Treatment variants viral infections virus [DOI] 10.3390/md19080406 PMC 바로가기 [Article Type] Article
Marine sulfated polysaccharides as potential antiviral drug candidates to treat Corona Virus disease (COVID-19)Review Published on 2021-05-032023-07-02 Journal: Carbohydrate Research [Category] SARS, [키워드] antivirals COVID-19 Drug repurposing immunomodulators SARS-CoV-2 sulfated polysaccharide [DOI] 10.1016/j.carres.2021.108326 PMC 바로가기 [Article Type] Review
The Potency of Seaweed Sulfated Polysaccharides for the Correction of Hemostasis Disorders in COVID-19Review Published on 2021-04-292022-10-30 Journal: Molecules [Category] COVID-19, MERS, [키워드] activities activity Anticoagulant Anticoagulants Antithrombotic Blood coagulation Carrageenans clinical manifestations clinical trial clinical trials Clinical use Combination complementary Compound compounds correction Course COVID-19 COVID-19 associated coagulopathy COVID-19 patient COVID-19 patients death develop disease disorder drug drugs effective Efficacy feature fibrinolytic fibrinolytics fucoidans glycosidic group Hemostasis hemostasis disorders hypercoagulability involved mechanism molecular weight optimal dose oral bioavailability outcome Pathogenesis pathophysiological mechanism potency progression researcher SARS-CoV-2 seaweed seaweed polysaccharides severe COVID-19 sulfated polysaccharide therapeutic potential thrombin inhibitors thrombolytics thrombotic complication Toxicity Treatment ulvans venous [DOI] 10.3390/molecules26092618 PMC 바로가기 [Article Type] Review
Inhibition of SARS-CoV-2 Virus Entry by the Crude Polysaccharides of Seaweeds and Abalone Viscera In Vitro해조류 및 전복 내장의 조다당류에 의한 SARS-CoV-2 바이러스 진입 억제 In VitroArticle Published on 2021-04-152022-09-10 Journal: Marine Drugs [Category] MERS, SARS, 치료제, [키워드] Abalone abalone viscera antioxidant antiviral activities antiviral activity antiviral agent Antiviral agents carbohydrate Codium COVID-19 discus except for fucoidan fucose Haliotis HEK293 IC50 indicated Infection inhibit SARS-CoV-2 inhibition inhibitory activity kDa Laminaria molecular weight MOST polysaccharide polysaccharides Porphyra Prevent pseudovirus Sargassum SARS-CoV-2 SARS-CoV-2 entry SARS-COV-2 infection SARS-CoV-2 pseudovirus SARS-CoV-2 virus screened seaweed sulfated sulfated polysaccharide the strongest Undaria pinnatifida viscera [DOI] 10.3390/md19040219 PMC 바로가기 [Article Type] Article