Early treatment of Favipiravir in COVID-19 patients without pneumonia: a multicentre, open-labelled, randomized control studyArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] 95% CI adjusted hazard ratio Antiviral antiviral. ARMS clinical clinical condition Clinical improvement complications control arm COVID-19 COVID-19 patient Day defined early treatment Effect Efficacy enrolled enrolment faster Favipiravir female FPV investigated likelihood median median time mild case mild pneumonia multicentre Patient PCR-confirmed Pneumonia primary endpoint randomized control study RdRP RdRp inhibitor registry risk of COVID-19 SARS-CoV-2-infected patient score significantly higher supportive care sustained symptomatic Thailand Treatment viral clearance Viral detection [DOI] 10.1080/22221751.2022.2117092 PMC 바로가기
Preparing for pandemics: a systematic review of pandemic influenza clinical management guidelinesArticle Published on 2022-11-072022-11-15 Journal: BMC Medicine [Category] 치료제, [키워드] addressed AGREE II Antiviral treatment appraisal benefit Care children clinical Clinical management Clinical management guidelines COVID-19 pandemic evaluate Evidence guideline help heterogeneous highlight identify Immunosuppression implementation Influenza International management management guideline median morbidity and mortality MOST neuraminidase inhibitor New Older outcomes OVID oxygen pandemic Patient populations Practice pregnant women preparedness Preparing produced recommendation reduce Research risk searched Support supportive care supportive care. systematic review therapy Treatment Trial Turning [DOI] 10.1186/s12916-022-02616-6 PMC 바로가기
Care for adults with COVID-19: living guidelines from the National COVID-19 Clinical Evidence TaskforceArticle Published on 2022-10-032022-11-15 Journal: The Medical journal of Australia [Category] COVID19(2023년), SARS, 진단, [키워드] Analysis anticoagulation Antiviral agents Baricitinib benefit change clinical clinical trial Combination coronavirus disease Corticosteroids COVID-19 disease disease severity drug treatment eight Endotracheal intubation Evidence facilitated Health include Inhaled maintain management Mild molnupiravir nine Patient people with COVID-19 positive airway pressure Primary Health Care prone positioning Prophylactic Prophylaxis Public public health. randomised recommendation recommendations Remdesivir Respiratory Support sarilumab subsequent supplemental oxygen Support supportive care systemic corticosteroids therapy Tocilizumab Treatment trials Venous Thromboembolism with COVID-19 [DOI] 10.5694/mja2.51718 PMC 바로가기
Effect of a diet based on Iranian traditional medicine on inflammatory markers and clinical outcomes in COVID-19 patients: A double-blind, randomized, controlled trialResearch article Published on 2022-10-012022-10-05 Journal: European Journal of Integrative Medicine [Category] 바이오마커, 임상, [키워드] traditional persian medicine acute respiratory syndrome Antiviral treatment appear approved baseline characteristics C-reactive protein cause caused Cicer Cicer arietinum Clinical outcome clinical trial Combination conducted control group cough COVID-19 COVID-19 patient COVID-19 patients demographics develop diagnosis of COVID-19 diet double-blind education Effect effective Efficacy and safety Ficus ficus carica headache help Hospitalization Inflammatory biomarker Inflammatory marker Intervention intervention group Iran Laboratory life-threatening Medicine Ministry of Health myalgia no significant difference Organ failure Patient randomized clinical trial randomized, controlled trial regimen Research Result Reza Safflower Sample size SARS-CoV-2 significant difference significantly lower SPSS software statistical analysis supportive care Symptom Symptoms Tehran Traditional Treatment treatment period Treatment protocol variables virus Vitis Vitis vinifera weakness while [DOI] 10.1016/j.eujim.2022.102179 [Article Type] Research article
A potent virucidal activity of functionalized TiO2 nanoparticles adsorbed with flavonoids against SARS-CoV-2Article Published on 2022-09-012022-11-15 Journal: Applied Microbiology and Biotechnology [Category] SARS, 치료제, [키워드] ACE-2 ACE-2 receptor Adsorption angiotensin-converting enzyme-2 Anti-SARS-CoV-2 Activity antiviral activity Antiviral effect antivirals binding block caused Cell Cell culture cell entry coronavirus SARS-CoV-2 COVID-19 Critical death demonstrated develop displaying Effect event Flavanone-7-O-glucoside flavonoid HCoV 229E Hesperetin-7-rutinoside host cell impair impairing imperative in vitro induce interact Interaction interfere management mechanism mental health molecular docking analysis Nanoparticulate compound pandemic receptor Region SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 spike glycoprotein SARS-CoV-2 spike glycoprotein. spike glycoprotein Spread supportive care targeted therapy the SARS-CoV-2 viral infection virucidal [DOI] 10.1007/s00253-022-12112-9 PMC 바로가기
Influence of the SARS-CoV-2 outbreak on management and prognosis of new lung cancer cases, a retrospective multicentre real-life cohort studyArticle Published on 2022-09-012022-11-16 Journal: European journal of cancer (Oxford, England : 1990 [Category] COVID19(2023년), SARS, 치료기술, [키워드] anticancer AP-HP Cancer patients Care categories clinical presentation cohort study collected COVID-19 Deleterious delivery delivery of health care diagnose diagnosed Early Cancer Early cancer detection Electronic health record Health hospitals impacted influence initial lockdown lung cancer lung cancer patient lung neoplasms management multicentre outbreak outcome pandemic Paris Patient Prognosis Quality Quality of Health Care receive recorded remained retrieved retrospective Routinely collected health data. SARS-CoV-2 pandemic supportive care survival the SARS-CoV-2 therapy Treatment treatment initiation university [DOI] 10.1016/j.ejca.2022.06.018 PMC 바로가기
Psychological impacts of COVID-19 pandemic in cancer patients on active treatmentResearch article Published on 2022-08-182022-10-05 Journal: Heliyon [Category] 진단, 치료법, [키워드] addition age Analysis Anxiety applied Cancer cancer patient Characteristics Chemotherapy clinician correlation COVID-19 COVID-19 infection COVID-19 pandemic DASS-21 Depression depressive determine develop diagnosed died disorder Effect evaluated high risk IES-R IES-R scores Impact Intervention investigated Mental pandemic Patient predict Psychiatric Psychological psychological condition Psychological distress psychological Impact Psychological intervention psychologically PTSD receive recognize recommendations Result risk serious complication severe complications Stress stress level supportive care Symptoms Treatment [DOI] 10.1016/j.heliyon.2022.e10142 [Article Type] Research article
Safety and practicality of high dose inhaled nitric oxide in emergency department COVID-19 patientsRandomized Controlled Trial Published on 2022-08-012022-10-05 Journal: The American journal of emergency medicine [Category] COVID19(2023년), SARS, 임상, [키워드] acute respiratory symptom addition Administered administration adverse effect Asymptomatic Complete Complication control group control patient controls Coronavirus disease 2019 COVID-19 COVID-19 patient Department determine died disease Donor Emergency emergency department enrolled evaluated group High dose High-dose IMPROVE In-vitro Inhaled inhibit Intubated Measures Mild nitric oxide Nitric oxide. not significant one patient Oxygenation Patient physician Physicians positive PPM practicality Prevent prevented progression Randomized randomized clinical trial receiving Replication respiratory symptom returned Safety SARS coronavirus 2 SARS-CoV-2 selective shown single dose subject supportive care Symptoms tested Treatment treatment group Treatment outcome vascular effects viruses [DOI] 10.1016/j.ajem.2022.04.052 PMC 바로가기 [Article Type] Randomized Controlled Trial
Supportive Care in Patients with Critical COVID-19Review article Published on 2022-08-012022-10-05 Journal: Infectious disease clinics of North America [Category] 임상, [키워드] COVID-19 Critical care High flow nasal cannula lung Noninvasive positive pressure ventilation Prone ventilation supportive care [DOI] 10.1016/j.idc.2022.08.003 [Article Type] Review article
Cost-Effectiveness Analysis of Molnupiravir Versus Best Supportive Care for the Treatment of Outpatient COVID-19 in Adults in the US미국 성인의 코로나19 외래환자 치료를 위한 몰누피라비르 대 최상의 지지 요법의 비용 효율성 분석Article Published on 2022-07-012022-09-11 Journal: PharmacoEconomics [Category] MERS, 바이오마커, 변종, [키워드] acute phase adult outpatient adult outpatients Adult patients affected Analysis Antiviral best Care changes changes in conducted coronavirus disease Coronavirus disease 2019 Cost effectiveness COVID-19 COVID-19 outpatients database de novo Decision tree decrease died dominant effective Electronic health record Electronic health records evaluated healthcare Healthcare system highest Hospitalization Hospitalized Immunity increase in information Intervention less Markov medical costs Mild-to-moderate molnupiravir outcome Outpatient pandemic parameter Patient patient population Perspective Primary outcomes Probability progression proportion real-world data reduction remained reported Research risk sensitivity analysis severe disease Society supportive care Therapies threshold transition transition probabilities treated treating COVID-19 Treatment Trial unavailability utility vaccination Viral Viral variants with COVID-19 [DOI] 10.1007/s40273-022-01168-0 PMC 바로가기 [Article Type] Article