Favipiravir for the treatment of COVID-19 in elderly patients—what do we know after 2 years of COVID-19?Short Communication Published on 2022-05-112023-07-02 Journal: GeroScience [Category] COVID19(2023년), SARS, [키워드] clinical trials Geriatrics severe acute respiratory syndrome coronavirus 2 T-705 [DOI] 10.1007/s11357-022-00582-8 PMC 바로가기 [Article Type] Short Communication
The Anti-Influenza Virus Drug Favipiravir Has Little Effect on Replication of SARS-CoV-2 in Cultured CellsLetter to the Editor Published on 2021-03-012022-10-27 Journal: Antimicrobial Agents and Chemotherapy [Category] COVID-19, [키워드] Avigan COVID-19 drug Effect Favipiravir Influenza SARS-CoV-2 T-705 [DOI] 10.1128/AAC.00020-21 PMC 바로가기 [Article Type] Letter to the Editor
Structure of the SARS-CoV-2 RNA-dependent RNA polymerase in the presence of favipiravir-RTPfavipiravir-RTP 존재 시 SARS-CoV-2 RNA 의존성 RNA 중합효소의 구조407 Published on 2021-02-162022-08-13 Journal: Proceedings of the National Academy of Sciences of [Category] Biochemistry, COVID-19, [키워드] (RdRp acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 approved bind binding binding pocket catalytic site clinical trial clinical trials complex conformation coronavirus COVID-19 pandemic cryoEM determine determined by develop drug Drug administration drug design drugs targeting effort enzyme Evidence explain Favipiravir FDA food help incorporation Infection information inhibitor Ion ions mechanism mechanism of action molecular basis nucleoside nucleoside analog nucleotide nucleotides polymerase polymerases RdRP Remdesivir Replication respiratory reveal RNA RNA polymerase RNA polymerase inhibitor RNA primer RNA-dependent RNA polymerase SARS coronaviruses SARS-CoV-2 SARS-CoV-2 RdRp SARS-CoV-2 RNA severe acute respiratory syndrome Coronavirus side chains Significance structural biology Structure suppresse T-705 Template the SARS-CoV-2 Treatment triphosphate US Food and Drug Administration Viral while [DOI] 10.1073/pnas.2021946118 PMC 바로가기 [Article Type] 407
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesisArticle Published on 2020-09-172022-10-04 Journal: Nature Communications [Category] SARS, 변종, 치료제, [키워드] Achille acute respiratory syndrome Antiviral effect antiviral therapeutics candidate caused clinical trial complex Corona coronavirus Coronavirus-2 COVID-19 cytosine inhibitor insertion mechanism of action Mutagenesis Nsp12 nucleoside analogue nucleotide pandemic polymerase provoking Rapid RdRP SARS-CoV SARS-CoV-2 SARS-CoV-2 genome T-705 Treatment Viral diseases Viral proteins Viral RNA [DOI] 10.1038/s41467-020-18463-z PMC 바로가기 [Article Type] Article
Growth activation of influenza virus by trypsin and effect of T-705 (favipiravir) on trypsin-optimized growth conditionArticle Published on 2019-01-012023-06-23 Journal: Acta virologica [Category] 신종인플루엔자, [키워드] bacterial trypsin-like protease. Influenza T-705 Tamiflu trypsin [DOI] 10.4149/av_2019_311
Combinations of favipiravir and peramivir for the treatment of pandemic influenza A/California/04/2009 (H1N1) virus infections in miceArticle Published on 2012-05-112023-06-09 Journal: Antiviral Research [Category] Fulltext, 신종인플루엔자, [키워드] Antiviral drug combination Favipiravir Peramivir T-705 [DOI] 10.1016/j.antiviral.2012.03.001 PMC 바로가기 [Article Type] Article