Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients
Research article
[키워드] acute respiratory syndrome
adoptive immunotherapy
analyses
approach
Autoimmunity
bystander
convalescent
Coronavirus-2
Course
COVID-19
COVID-19 cases
COVID-19 immunopathology
CRISPR-Cas9
death
Donor
Efficiency
efficient clearance
flow cytometry
high risk
immune response
immunopathology
Immunosuppressed
immunosuppressed patient
Immunosuppression
Immunotherapy
increased risk
Infection
manifested
Patient
Prevent
receive
recipient
recipients
reduced
ribonucleoprotein
RNA
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2-specific T cell
Sequencing
severe coronavirus disease
severe COVID-19
single-cell
single-cell level
solid organ
Solid organ transplant recipients
SOT
SOT patient
specificity
T cell
T cell activation
T cell receptor
T cell therapy
TCR
therapeutic
transfer
treat
Vaccine
Vaccines
viral clearance
viral infection
[DOI] 10.1016/j.omtm.2022.02.012 [Article Type] Research article
[DOI] 10.1016/j.omtm.2022.02.012 [Article Type] Research article