Evaluation of the prevalence of new-onset musculoskeletal symptoms in patients hospitalized for severe SARS-CoV2 infection during the first two COVID waves in France: a descriptive analysis of the clinical data warehouse of 39 hospitals in FranceResearch article Published on 2022-11-012022-10-05 Journal: Joint bone spine [Category] SARS, 치료제, [키워드] Analysis Antiviral arthralgia Arthritis assistance back pain Characteristics Chi2 clinical Clinical data Cohort collected comorbid patients condition Corticosteroid COVID Descriptive analysis determine diabete discharge disease expression France had no hospital hypertensive ICD-10 in both group in both groups include Musculoskeletal musculoskeletal symptom obese objective occurred Older Pain Paris Patient patients hospitalized patients treated positive positive RT-PCR Prevalence prevalent Result SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RT-PCR SARS-CoV2 infection Symptom t-test these symptom Treatment viral infection warehouse were excluded [DOI] 10.1016/j.jbspin.2022.105450 [Article Type] Research article
The impact of COVID-19 restrictions on participant enrollment in the PREPARE trialResearch article Published on 2022-10-012022-10-05 Journal: Contemporary Clinical Trials Communications [Category] 임상, [키워드] affected approval clinical trials COVID-19 COVID-19 pandemic COVID-19 research Enrollment Evaluating extremities implementation interquartile range median pandemic participant Patient Pragmatic pragmatic trials PREPARE trial protocol recorded researcher Result significantly lower skin solution t-test Trial [DOI] 10.1016/j.conctc.2022.100973 [Article Type] Research article
The changing spectrum of microbial aetiology of respiratory tract infections in hospitalized patients before and during the COVID-19 pandemicArticle Published on 2022-09-302022-11-15 Journal: BMC Infectious Diseases [Category] SARS, 치료기술, [키워드] 95% CI Admission aetiology Bacteria Bacterial Bergen categorical data Cohort cohorts Community community acquired community acquired pneumonia conducted containment measures COVID COVID-19 COVID-19 pandemic declined Electronic health record Epidemiology FilmArray pneumonia panel Fisher Haemophilus influenzae hospital Hospital admission hospitalized patient infection control less Lower respiratory tract Mann-Whitney measure microbial molecular testing outbreak pathogen Patient patients Pneumonia proportion Prospective Study reducing respiratory respiratory tract infection Respiratory tract infections SARS-CoV-2 significantly lower specimens Spread Staphylococcus aureus Streptococcus pneumoniae surveillance data t-test Trust variables virus was used [DOI] 10.1186/s12879-022-07732-5 PMC 바로가기
Clinical characteristics and outcomes of the multisystem inflammatory syndrome in children (MIS-C) following COVID-19 infection in Iran: A multicenter studyArticle Published on 2022-09-222022-11-15 Journal: PLoS ONE [Category] SARS, 진단, [키워드] Admission Analysis CDC Characteristics Chi-square children clinical Clinical characteristics Clinical sign collected Comorbidities Comorbidity Control COVID-19 COVID-19 infection criteria demographic characteristics died discharged drug epidemiological FIVE Gastrointestinal geographical region hematologic Inflammatory injection Iran Laboratory Lung CT median median age MIS-C MOST Most patient multicenter multicenter observational study obesity outcome Patient patients Positive test prevention RT-PCR serology steroid Steroids Symptoms syndrome t-test tested the patient tongue treated Treatment two group two groups [DOI] 10.1371/journal.pone.0274104 PMC 바로가기
Antibody response to BNT162b2 SARS-CoV-2 mRNA vaccine in adult patients with systemic sclerosisArticle Published on 2022-09-012022-11-15 Journal: Clinical Rheumatology [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI Affect Antibody titer BNT162b2 CCS Clinical characteristics Cohort Comorbidity Corticosteroids COVID-19 difference disease evaluated Fisher exact test healthy control humoral Humoral response Immunosuppression immunosuppressive Immunosuppressive treatment IQR Logistic regression analysis low dose Mann-Whitney methotrexate mRNA vaccination mRNA vaccine MTX Patient patients patients treated Point reduced Regression model risk RTX SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine second dose serological response seropositive Seropositivity serum IgG severe disease course student systemic Systemic sclerosis t-test therapy Treatment untreated patient vaccination Vaccine vaccine-induced antibody [DOI] 10.1007/s10067-022-06219-7 PMC 바로가기
Comparison of the effect of intravenous dexamethasone and methylprednisolone on the treatment of hospitalized patients with COVID-19: a randomized clinical trialRandomized Controlled Trial Published on 2022-09-012022-10-04 Journal: International Journal of Infectious Diseases [Category] COVID19(2023년), SARS, 바이오마커, 임상, 치료법, [키워드] addition Admission age analysis of variance analyzed assigned confidence interval COVID-19 Dexamethasone doses duration of hospitalization Effect Effectiveness enrolled Hospital stay Hospitalization hospitalized patient hyperglycemia hypokalemia Inpatient intensive care intravenous leukocyte Lymphocyte count Methylprednisolone methylprednisolone group moderate Mortality mortality rate Oxygen therapy Patient Primary outcome protocol randomized clinical trial Randomly Result secondary outcome severe COVID-19 significantly SPSS statistically significant t-test therapeutic Treatment two group with COVID-19 [DOI] 10.1016/j.ijid.2022.07.019 PMC 바로가기 [Article Type] Randomized Controlled Trial
Age- and sex-based changes in spike protein antibody status after SARS-CoV-2 vaccination and effect of past-infection in healthcare workers in OsakaArticle Published on 2022-08-262022-11-15 Journal: BMC Infectious Diseases [Category] SARS, 진단, [키워드] age Age group All participant antibody antibody status Antibody titre assays association Blood changes in different time point examined follow-up time healthcare worker investigated men not different nucleocapsid protein Nucleocapsid protein antibody participant Peripheral blood positive positive correlation Protein provided reduction in SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 vaccination second vaccination Seven Sex shown significant negative correlation significantly higher spike Spike protein Spike protein antibody. t-test titre vaccination were assessed women Yao [DOI] 10.1186/s12879-022-07695-7 PMC 바로가기
More Accessible COVID-19 Treatment Through Monoclonal Antibody Infusion in the Emergency DepartmentArticle Published on 2022-08-192022-11-15 Journal: Western Journal of Emergency Medicine [Category] 진단, [키워드] antibody black categorical variable Characteristics Community Complication Coronavirus 2019 COVID-19 cross-sectional Department disease Emergency examined Health healthcare Healthcare system Hispanic increased risk infusion Medicaid National New occur Patient performed positive presenting proportion retrospective risk Robert severe COVID-19 illness social determinant statistically significant t-test tested therapy Treatment two group university variables wood [DOI] 10.5811/westjem.2022.5.55234 PMC 바로가기
Prevalence, Causes, and Adverse Clinical Impact of Delayed Presentation of Non-COVID-19-Related Emergencies during the COVID-19 Pandemic: Findings from a Multicenter Observational StudyObservational Study Published on 2022-08-092022-10-04 Journal: International Journal of Environmental Research an [Category] 임상, [키워드] 28-day mortality Admission Adverse Bahrain calculate clinical Clinical outcome Comparisons coronavirus disease COVID-19 COVID-19 pandemic Delayed delayed presentation diagnose diagnoses Emergency emergency department enrolled evaluated Factor fear finding group Healthcare system hospital hospitalized patient ICU identify Impact intensive care Invasive mechanical ventilation IQR median Mortality Non-COVID-19 non-COVID-19 emergencies. onset of symptom outcome pandemic Patient patients hospitalized presentation Prevalence Primary outcome regression analysis resulting Saudi Arabia secondary outcome seeking significantly higher study period surgical t-test tertiary care hospital was performed were used [DOI] 10.3390/ijerph19169818 PMC 바로가기 [Article Type] Observational Study
Serological response to a third booster dose of BNT162b2 COVID-19 vaccine among seronegative cancer patients혈청 음성 암 환자에서 BNT162b2 COVID-19 백신의 3차 추가 접종에 대한 혈청학적 반응Article Published on 2022-08-012022-09-11 Journal: Cancer Reports [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] Administered antibody Antibody Response anticancer BNT162b2 booster booster dose Cancer cancer patient COVID-19 COVID-19 vaccine detect domain dose elicit ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated IgG IgG titers Immunoglobulin Immunoglobulin G of BNT162b2 Patient Patients with cancer Pfizer/BioNTech pilot study Receptor-binding domain Sample SARS-CoV-2 second vaccination serological response seronegative seropositive small sample size student t-test the RBD two-sided vaccine dose vaccine doses [DOI] 10.1002/cnr2.1645 PMC 바로가기 [Article Type] Article