SARS-CoV-2 Nucleocapsid Protein Induces Tau Pathological Changes That Can Be Counteracted by SUMO2Article Published on 2024-06-282024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] memory nucleocapsid protein SARS-CoV-2 stress granules SUMO synapses Tau [DOI] 10.3390/ijms25137169 PMC 바로가기 [Article Type] Article
Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer’s diseaseResearch Article Published on 2024-06-212024-09-05 Journal: Alzheimer's & dementia : the journal of the Alzhei [Category] update2024, [키워드] Alzheimer's disease Biomarkers glial cells nonhuman primates Tau [DOI] 10.1002/alz.13868 PMC 바로가기 [Article Type] Research Article
Severe acute respiratory syndrome coronavirus 2 infection leads to Tau pathological signature in neuronsBiological, Health, and Medical Sciences Published on 2023-09-192024-09-05 Journal: PNAS Nexus [Category] update2024, [키워드] COVID-19 neuro-COVID phospho-Tau SARS-CoV-2 Tau [DOI] 10.1093/pnasnexus/pgad282 PMC 바로가기 [Article Type] Biological, Health, and Medical Sciences
The Alzheimer’s Disease Neuroimaging Initiative in the era of Alzheimer’s disease treatment: A review of ADNI studies from 2021 to 2022Review Article Published on 2023-09-122024-09-05 Journal: Alzheimer's & dementia : the journal of the Alzhei [Category] update2024, [키워드] Alzheimer's disease clinical trials Alzheimer's Disease Neuroimaging Initiative Alzheimer's disease subtypes amyloid Cerebrovascular disease co‐pathologies Diagnosis Disease progression Generalizability neurodegeneration Neuroinflammation plasma biomarkers prediction Resilience Tau [DOI] 10.1002/alz.13449 PMC 바로가기 [Article Type] Review Article
Effectiveness and Safety of Bu Shen Kai Qiao Fang in the Treatment of Alzheimer’s Disease: Study Protocol for a Multicenter, Prospective, Real-World Clinical TrialStudy Protocol Published on 2023-06-172024-09-05 Journal: International Journal of General Medicine [Category] update2024, [키워드] Alzheimer’s disease Aβ42 Bu Shen Kai Qiao Fang MMSE MoCA real-world trial Tau [DOI] 10.2147/IJGM.S418700 PMC 바로가기 [Article Type] Study Protocol
The gut microbiome in Alzheimer’s disease: what we know and what remains to be exploredarticle Published on 2023-02-012024-09-05 Journal: Molecular Neurodegeneration [Category] update2024, [키워드] amyloid diet exercise gut microbiome Human mouse Neuroinflammation Peripheral immunity Sleep Tau Therapeutics [DOI] 10.1186/s13024-023-00595-7 PMC 바로가기 [Article Type] article
Unconventional protein secretion (UPS): role in important diseasesarticle Published on 2023-01-092024-09-05 Journal: Molecular Biomedicine [Category] update2024, [키워드] Alzheimer’s Cancer Diseases Ectosomes and exosomes endocytosis Exocytosis Interconnected UPS membrane fusion neurodegeneration Tau therapy UPS = Unconventional Protein Secretion [DOI] 10.1186/s43556-022-00113-z PMC 바로가기 [Article Type] article
Building Emotional Awareness and Mental Health (BEAM): study protocol for a phase III randomized controlled trial of the BEAM app-based program for mothers of children 18-36 monthsArticle Published on 2022-09-052022-10-05 Journal: Trials [Category] 임상, [키워드] Anxiety anxiety symptoms assessment Awareness build building children Cohort COVID-19 pandemic Depression Efficacy elevated emotion evaluate finding Follow-up Health IMPROVE improvement individual Intervention Maternal mental health mental health disorders mental illness mother occur pandemic Parenting pregnant Prevalence Primary outcome programming Psychoeducation Randomized Randomized controlled trial RCT RCT. recruited reducing repeated measure risk Secondary outcomes Stress Study protocol Support Symptom Symptoms symptoms of depression Tau treatment as usual treatment group Trial Two-arm used to evaluate [DOI] 10.1186/s13063-022-06512-5 PMC 바로가기 [Article Type] Article
Evaluation of competency-driven training for facilitators delivering a psychological intervention for children in Lebanon: a proof-of-concept studyRandomized Controlled Trial Published on 2022-07-112022-10-05 Journal: Epidemiology and Psychiatric Sciences [Category] 임상, [키워드] activity added Analysis approach assessment benefit children common competency contribute COVID-19 pandemic demonstrated distress effective delivery eliminating emotional evaluate Evidence experimental arm facilitator Factor form greater group increase in Intervention Mann-Whitney U measure mental health outcome Psychological intervention quality indicators quality of care Randomly rapid expansion recommendation reduction repeated significantly statistically significant Support task sharing. Tau Trial working [DOI] 10.1017/S2045796022000348 PMC 바로가기 [Article Type] Randomized Controlled Trial
Online Telehealth Delivery of Group Mental Health Treatment Is Safe, Feasible, and Increases Enrollment and Attendance in Post-9/11 U.S. VeteransRandomized Controlled Trial Published on 2022-05-012022-10-05 Journal: Behavior therapy [Category] 임상, [키워드] age Attendance Care clinically Community complex connection coronavirus disease COVID-19 delivery dose effective Enrollment evaluated exacerbated feasibility females greater group group therapy Health health condition IMPROVE increase Increased Isolation likelihood mental health morbidity and mortality no difference occurred offer participated Patient problems Psychiatric Quality of life Randomized receive receiving reintegration Result risk Safety Satisfaction social distancing Strong Support synchronous Tau TAU group telehealth therapist therapy Treatment treatment as usual U.S. veterans, feasibility underutilization veteran [DOI] 10.1016/j.beth.2021.11.004 PMC 바로가기 [Article Type] Randomized Controlled Trial