Electrochemical Behavior of Janus Kinase Inhibitor Ruxolitinib at a Taurine-Electropolymerized Carbon Paste Electrode: Insights into Sensing Mechanismsarticle Published on 2024-04-062024-09-05 Journal: ACS applied bio materials [Category] update2024, [키워드] Electrochemical oxidation electropolymerization Janus kinase inhibitor ruxolitinib Taurine [DOI] 10.1021/acsabm.4c00186 PMC 바로가기 [Article Type] article
GABA A receptors as plausible molecular targets and mediators for taurine and homotaurine actionsPharmacology Brief Research Report Published on 2023-12-142024-09-05 Journal: Frontiers in Pharmacology [Category] update2024, [키워드] Alzheimer’s disease GABA-mimetics homotaurine Inflammation Taurine tramiprosate [DOI] 10.3389/fphar.2023.1271203 PMC 바로가기 [Article Type] Pharmacology Brief Research Report
Metabolomics-based investigation of SARS-CoV-2 vaccination (Sinovac) reveals an immune-dependent metabolite biomarkerArticle Published on 2022-09-282022-11-15 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 변종, 진단, [키워드] analyses Analysis antibodies and cytokines antibody association AUC Biomarker boost butanoate collected COVID-19 COVID-19 vaccine Cytokines determine effective fatality FDR Fold change GABA Glutamate greater help Host host immunity IgA IgG IgM immune Immunity IMPROVE individual indole Infection L-glutamic acid metabolism metabolite metabolome metabolomic metabolomic analysis metabolomics mutant strain mutated Pathways positive pre-vaccination provide respond reveal SARS-CoV-2 SARS-CoV-2 vaccination SARS-CoV-2 virus infection sera serum serum antibody Sinovac Spread Taurine vaccination Vaccine VIP Volunteer was performed [DOI] 10.3389/fimmu.2022.954801 PMC 바로가기
Long-Term Dietary Taurine Lowers Plasma Levels of Cholesterol and Bile AcidsArticle Published on 2022-02-042023-08-30 Journal: International Journal of Molecular Sciences [Category] E형 간염, [키워드] bile acid cholesterol CYP7A1 ERK FGF21 Taurine [DOI] 10.3390/ijms23031793 PMC 바로가기 [Article Type] Article
The serum amino acid profile in COVID-19COVID-19의 혈청 아미노산 프로필Clinical Trial Published on 2021-10-012022-09-11 Journal: Amino acids [Category] MERS, SARS, 바이오마커, 비임상, 임상, 치료기술, [키워드] addition Affect Amino acid amino acid metabolism amino acids BCAA BCAAs Biomarker branched-chain amino acid branched-chain amino acids breath can be used caused changed conducted control group coronavirus coronavirus disease correlation Course COVID patient Covid patients COVID-19 COVID-19 patient COVID-19 patients Determining develop Diagnosis Diseases examined group healthy Impact Infection information l-2-aminobutyric acid. L-phenylalanine Laboratory metabolism Mild moderate pandemic patient groups patients with asymptomatic Phenylalanine profile Prognosis prognostic SARS-CoV-2 SARS-COV-2 infection serum severity significant difference significant differences statistical analyses statistical analysis subject Taurine the disease Treatment treatment protocols [DOI] 10.1007/s00726-021-03081-w PMC 바로가기 [Article Type] Clinical Trial
Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome급성기 비입원 COVID-19 환자의 불완전한 전신 회복 및 대사성 표현 전환: Post-Acute COVID-19 증후군 평가에 대한 시사점Article Published on 2021-06-042022-09-11 Journal: Journal of Proteome Research [Category] SARS, 치료기술, [키워드] acute COVID-19 acute respiratory syndrome adaptive amino acids Analysis analyzed Anosmia approach assessment Asymptomatic biochemical Biomarker Biomarkers blood sample Blood samples Chronic fatigue Control controls Correlation analysis cough COVID-19 COVID-19 infection COVID-19 patient COVID-19 patients discriminant analysis Dyspnea elevated exhibiting Follow-up functional Functional assessment Glutamate Glutamine Glycoproteins greater healthy control healthy controls Hospitalized immune immune function in some Incomplete Infection joint joint pain Kynurenine Lipoproteins liver long-COVID long-COVID syndrome mass spectrometry metabolic Metabolic data metabolites Multiorgan multiorgan disease multiple parameter multiple parameters myalgia NMR nuclear magnetic resonance Other Pain parameter pathophysiology pathway Patient patients PCA phenoconversion phenoreversion phenotype plasma plasma samples Post-acute COVID-19 syndrome Principal component principal component analysis reduced reduction in remained resonance respiratory-related symptom respiratory-related symptoms rhinorrhea SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positive patient Severe acute respiratory syndrome Significant significantly significantly lower Spectrum Symptom symptomatic symptomatic patient Symptomatic patients syndrome systemic systemic inflammatory Taurine the healthy the patient tissue repair Tryptophan was normalized [DOI] 10.1021/acs.jproteome.1c00224 PMC 바로가기 [Article Type] Article
SARS-CoV-2 infection paralyzes cytotoxic and metabolic functions of the immune cellsResearch Article Published on 2021-05-282022-10-31 Journal: Heliyon [Category] COVID-19, [키워드] 1H-NMR Acetate acute respiratory distress ARDS autologous CD8 CD8+ T cells change characterized convalescent COVID-19 patients convalescent patient Convalescent patients COVID-19 Cytometry cytotoxic function elevated expression Flow flow cytometry Glutamate granzyme Granzyme A Immune cell immune cells immune response infectious disease outbreak interfere investigated Lactate metabolic function metabolites Mild moderate Moderate COVID-19 mononuclear cell Patient patients PBMCs perforin Peripheral blood SARS-COV-2 infection SARS-CoV-2 virus significantly suggested syndrome T cell T cells Taurine virus [DOI] 10.1016/j.heliyon.2021.e07147 PMC 바로가기 [Article Type] Research Article
Bromamine T, a stable active bromine compound, prevents the LPS-induced inflammatory responseArticle Published on 2021-04-032024-09-04 Journal: International Journal of Molecular Medicine [Category] 대상포진, [키워드] air-pouch model of inflammation bromamine T pro-inflammatory cytokines Taurine [DOI] 10.3892/ijmm.2021.4870 PMC 바로가기 [Article Type] Article
Role of taurine, its haloamines and its lncRNA TUG1 in both inflammation and cancer progression. On the road to therapeutics? (Review)Article Published on 2020-09-142024-09-04 Journal: International journal of oncology [Category] 대상포진, [키워드] Cancer Inflammation Taurine taurine haloamines taurine upregulated gene 1 ncRNA [DOI] 10.3892/ijo.2020.5100 PMC 바로가기 [Article Type] Article
Is cancer a severe delayed hypersensitivity reaction and histamine a blueprint?Perspective Published on 2016-08-232023-08-30 Journal: Clinical and Translational Medicine [Category] E형 간염, [키워드] aging allergy Angiogenesis bioenergetics Branched amino acids Cancer Fetal growth Histamine hypersensitivity Immune-privileged and immune-responsive tissues Mitochondria Placenta Taurine Yin and Yang of inflammation [DOI] 10.1186/s40169-016-0108-3 PMC 바로가기 [Article Type] Perspective