Potential molecular mechanisms of zinc- and copper-mediated antiviral activity on COVID-19
Review
[키워드] ACE2, Angiotensin-converting enzyme-2
ARDS, acute respiratory distress syndrome
ATOX1, human antioxidant protein 1
ATP7A, copper-ATPase
Bax, bcl-2-like protein 4
Bcl-2, B-cell lymphoma 2
CCS, copper chaperone for superoxide dismutase
Copper (Cu)
Coronavirus disease 2019 (COVID-19)
CTR1, copper transporter protein
Cu, copper
gastrointestinal system
IFN, Interferons
IL, interleukin
MRE, metal-responsive element
MT, metallothionein
MTF-1, metal-responsive transcription factor-1
NAD, dependent deacetylase sirtuin-1
NF-κB, nuclear factor-κB
NK cells, Natural Killer cells
Nrf 2, nuclear erythroid factor 2
RdRp, RNA dependent RNA polymerase
ROS, reactive oxygen species
SARS-COV-2, severe acute respiratory syndrome coronavirus-2
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
SIRT1, NAD-dependent deacetylase sirtuin-1
SOD, Superoxide dismutase
Th, T helper cell
trace elements
Zinc (Zn)
ZIP, Zrt-/Irt-like protein
Zn, zinc
ZnT, zinc transporter
Zo-1, zonula occludens-1
[DOI] 10.1016/j.nutres.2021.05.008 PMC 바로가기 [Article Type] Review
[DOI] 10.1016/j.nutres.2021.05.008 PMC 바로가기 [Article Type] Review