A conserved antigen induces respiratory Th17-mediated broad serotype protection against pneumococcal superinfection보존된 항원이 폐렴구균 중복 감염에 대한 호흡기 Th17 매개 광범위 혈청형 보호를 유도한다.Article Published on 2024-03-132024-08-24 Journal: Cell Host & Microbe [Category] 폐렴구균 감염증, [키워드] CRISPRi-seq genome-wide vaccinology intranasal vaccine Non-vaccine serotypes pneumococcus protein antigen superinfection Th17 tissue-resident memory T lymphocytes vaccine discovery.
The effect of SARS-CoV-2 infection and vaccination on Th17 and regulatory T cells in a pregnancy cohort in NYCImmunology Brief Research Report Published on 2024-03-052024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] COVID-19 pandemic COVID-19 vaccination Ratio SARS-COV-2 infection Th17 Treg [DOI] 10.3389/fimmu.2024.1350288 PMC 바로가기 [Article Type] Immunology Brief Research Report
Th2 and Th17-Associated Immunopathology Following SARS-CoV-2 Breakthrough Infection in Spike-Vaccinated ACE2-humanized MiceArticle Published on 2023-10-192024-09-05 Journal: bioRxiv [Category] update2024, [키워드] Breakthrough infection eosinophil pulmonary immunopathology Spike Protein Vaccine Th17 Th2 [DOI] 10.1101/2023.10.18.563016 PMC 바로가기 [Article Type] Article
Dysregulation of T Cell Differentiation and the IL17A(+)Foxp3(+)Treg Subset in Chronic Hepatitis B Patients with Hepatitis Flare만성 간염 B 환자에서 간염 플레어와 관련된 T 세포 분화 및 IL17A(+)Foxp3(+)Treg 하위 집단의 조절 이상Article Published on 2023-03-012023-06-01 Journal: Viral immunology [Category] A형 간염, B형 간염, [키워드] FOXP3 IL17A(+)Foxp3(+)Treg RORγt Th17 Treg [DOI] 10.1089/vim.2022.0140
The balance between lung regulatory T cells and Th17 cells is a risk indicator for the acute exacerbation of interstitial lung disease after surgery: a case-control studyarticle Published on 2023-02-222024-09-05 Journal: BMC Pulmonary Medicine [Category] update2024, [키워드] acute exacerbation idiopathic interstitial pneumonia Regulatory T cell surgery Th17 [DOI] 10.1186/s12890-023-02362-2 PMC 바로가기 [Article Type] article
Increased Pro Th1 And Th17 Transcriptional Activity In Patients With Severe COVID-19Research Paper Published on 2023-02-212024-09-05 Journal: International Journal of Medical Sciences [Category] update2024, [키워드] CD4+ T cells COVID-19 severity RORγt Tbet Th1 Th17 [DOI] 10.7150/ijms.80498 PMC 바로가기 [Article Type] Research Paper
A high CMV-specific T cell response associates with SARS-CoV-2-specific IL-17 T cell productionArticle Published on 2023-02-012023-07-11 Journal: Medical Microbiology and Immunology [Category] COVID19(2023년), [키워드] cellular immunity Cytokines cytomegalovirus Lymphocytes SARS-CoV-2 Th17 [DOI] 10.1007/s00430-022-00758-1 PMC 바로가기
Adaptive immunity to SARS-CoV-2 infection: A systematic reviewArticle Published on 2022-10-102022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute respiratory syndrome adaptive Adaptive immunity addressed Alpha Antigen article B cell Biomarker case-control study caused CD4+ T cell CD8+ CD8+ T lymphocytes Cell cell types Characteristics clinical benefits Cohort studies coronavirus coronavirus disease Course COVID-19 Critically ill Critically ill patient cross-sectional CXCL9 Cytokines database disease English Evidence experimental evidence follicular HLA-DR humoral Humoral immunity IL-10 IL-13 IL-15 IL-17 IL-1α IL-2 IL-21 IL-22 IL-23 IL-4 IL-5 IL-7 immune system Immunity immunological Immunological memory immunopathological in vitro assays individuals inflammatory mediator involved leukocyte Ligand lymphocyte marker mild case Necrosis poor prognosis predominant produced programmed cell death progression Protein Regulatory T cell responsible SARS-CoV-2 SARS-COV-2 infection SciELO secretion severity Spanish subpopulation systematic review T helper T helper cell T lymphocyte T-cell Response Tfh TGF-β Th1 Th17 Th2 the antibody the disease TNF-α Treg tumor growth Vaccine variable [DOI] 10.3389/fimmu.2022.1001198 PMC 바로가기
Prophylactic treatment of Glycyrrhiza glabra mitigates COVID-19 pathology through inhibition of pro-inflammatory cytokines in the hamster model and NETosisArticle Published on 2022-09-272022-11-16 Journal: Frontiers in Immunology [Category] SARS, 변종, [키워드] accompanied acute respiratory distress addition Comorbidity coronavirus disease COVID-19 COVID-19 pathology cytokine production decrease dysregulated immune response effective Efficacy Evidence functions glycyrrhiza Glycyrrhiza glabra Hamster model hamsters hypercoagulable IL-17A IL-4 immunocompromised individuals immunomodulator immunomodulatory properties Inflammatory cytokine ingredient Lung pathology lung viral load mice mice and human neutrophil functions. mitigate Mortality mRNA expression murine NET NETosis neutrophil polymorphonuclear neutrophil pro-inflammatory cytokine Protective provide Pulmonary pathology reduced reducing robust ROS SARS-CoV-2 SARS-COV-2 infection skewed suppress syndrome Th17 Th2 Th2/Th17 differentiation Treatment vaccination Vaccine variant [DOI] 10.3389/fimmu.2022.945583 PMC 바로가기
Network analysis for elucidating the mechanisms of Shenfu injection in preventing and treating COVID-19 combined with heart failureResearch article Published on 2022-09-012022-10-05 Journal: Computers in biology and medicine [Category] COVID19(2023년), SARS, 바이오마커, 유전자 메커니즘, [키워드] acting acute respiratory syndrome Analysis approach biological process biological processe caused cell differentiation China Chinese components Compound compound screening coronavirus COVID-19 COVID-19 case Critical cytokine signaling Cytoscape Cytoscape software Diagnosis drug-likeness Effectiveness enrichment analysis Evidence heart failure Hemostasis identify IL-17 immune system indicated Infection Inflammatory response injection involved KEGG pathway Kyoto Lung injury mechanism Medicine National Health Commission network network analysis novel coronavirus disease objective overlapped Pathway analysis Pathway enrichment analysis Pathways patients with COVID-19 pharmacological mechanism Pharmacological mechanisms Pharmacology progression protein-protein interaction regulated Respiratory failure Result SARS-CoV-2 Shenfu injection signaling pathway Stage suggested syndrome System target targets TCM Th17 therapeutic therapy Traditional treat treating COVID-19 Treatment was used [DOI] 10.1016/j.compbiomed.2022.105845 [Article Type] Research article