Immune signature in vaccinated versus non-vaccinated aged people with COVID-19 pneumoniaResearch Published on 2024-08-122024-09-05 Journal: Journal of Translational Medicine [Category] update2024, [키워드] COVID-19 disease severity COVID-19 vaccine elderly Immunological response Non-vaccinated plasma cytokines Pneumonia SARS-CoV-2 variants Th2 [DOI] 10.1186/s12967-024-05556-2 PMC 바로가기 [Article Type] Research
Trichinella spiralis Infection Inhibits the Efficacy of RBD Protein of SARS-CoV-2 Vaccination via Regulating Humoral and Cellular ImmunityArticle Published on 2024-06-302024-09-05 Journal: Vaccines [Category] update2024, [키워드] ALB COVID-19 GC B cells T. spiralis Th2 Treg vaccine efficacy [DOI] 10.3390/vaccines12070729 PMC 바로가기 [Article Type] Article
Visceral Leishmaniasis in Immunocompetent Hosts in Brescia: A Case Series and Analysis of Cytokine CascadeCase Report Published on 2024-02-162024-09-05 Journal: Microorganisms [Category] update2024, [키워드] Brescia Cytokines IFN-γ Immunocompetent host Leishmania neglected disease Parasitic zoonosis Th1 Th2 visceral leishmaniasis [DOI] 10.3390/microorganisms12020394 PMC 바로가기 [Article Type] Case Report
DNA Vaccines: Their Formulations, Engineering and DeliveryReview Published on 2024-01-112024-09-05 Journal: Vaccines [Category] update2024, [키워드] Adaptive immunity adjuvant delivery DNA vaccine Gene therapy immune responses Inflammatory Innate immunity integration Th1 Th2 Tolerance vector [DOI] 10.3390/vaccines12010071 PMC 바로가기 [Article Type] Review
Th2 and Th17-Associated Immunopathology Following SARS-CoV-2 Breakthrough Infection in Spike-Vaccinated ACE2-humanized MiceArticle Published on 2023-10-192024-09-05 Journal: bioRxiv [Category] update2024, [키워드] Breakthrough infection eosinophil pulmonary immunopathology Spike Protein Vaccine Th17 Th2 [DOI] 10.1101/2023.10.18.563016 PMC 바로가기 [Article Type] Article
Asthma and COVID-19: a controversial relationshiparticle Published on 2023-09-072024-09-05 Journal: Virology Journal [Category] update2024, [키워드] allergy Asthma atopy COVID-19 IL-13 IL-33 lockdown Mexico SARS-CoV2 Th2 [DOI] 10.1186/s12985-023-02174-0 PMC 바로가기 [Article Type] article
Humoral and cellular immune responses to CoronaVac up to one year after vaccinationArticle Published on 2022-10-212022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] all subject Antibody Response Antiviral CD4^{+} T cell cellular Cellular immune response cellular response clinical trial CoronaVac cytokine production cytokine profile defined effector memory evaluated follicular humoral Humoral response immune immune memory immune response impacted Inactivated vaccine individual induce memory Older peaked Phase 3 response SARS-CoV-2 SARS-CoV-2-specific IgG SARS-CoV-2-specific immune responses second dose sustained T cell activation T cell phenotype Tfh Th2 vaccination vaccine dose vaccinees [DOI] 10.3389/fimmu.2022.1032411 PMC 바로가기
SARS-CoV-2 Variant-Specific Infectivity and Immune Profiles Are Detectable in a Humanized Lung Mouse ModelArticle Published on 2022-10-162022-11-15 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] animal model B.1.1.7 B.1.1.7 variant expected greater higher infectivity Human immune system human lung tissue humanized humanized mice immune cells Immune profile immune response Immunity Infection Infectivity lesion Lineage lung lung organoid mice Model mouse no difference overlapping Pathogenesis pathogenesis of SARS-CoV-2 profile replication of SARS-CoV-2 required Research SARS-CoV-2 SARS-COV-2 infection similarity Support supported sustained Th1 Th2 variant variants of concern Viral load viral variant Viral variants virus [DOI] 10.3390/v14102272 PMC 바로가기
Adaptive immunity to SARS-CoV-2 infection: A systematic reviewArticle Published on 2022-10-102022-11-15 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute respiratory syndrome adaptive Adaptive immunity addressed Alpha Antigen article B cell Biomarker case-control study caused CD4+ T cell CD8+ CD8+ T lymphocytes Cell cell types Characteristics clinical benefits Cohort studies coronavirus coronavirus disease Course COVID-19 Critically ill Critically ill patient cross-sectional CXCL9 Cytokines database disease English Evidence experimental evidence follicular HLA-DR humoral Humoral immunity IL-10 IL-13 IL-15 IL-17 IL-1α IL-2 IL-21 IL-22 IL-23 IL-4 IL-5 IL-7 immune system Immunity immunological Immunological memory immunopathological in vitro assays individuals inflammatory mediator involved leukocyte Ligand lymphocyte marker mild case Necrosis poor prognosis predominant produced programmed cell death progression Protein Regulatory T cell responsible SARS-CoV-2 SARS-COV-2 infection SciELO secretion severity Spanish subpopulation systematic review T helper T helper cell T lymphocyte T-cell Response Tfh TGF-β Th1 Th17 Th2 the antibody the disease TNF-α Treg tumor growth Vaccine variable [DOI] 10.3389/fimmu.2022.1001198 PMC 바로가기
Intranasal vaccination induced cross-protective secretory IgA antibodies against SARS-CoV-2 variants with reducing the potential risk of lung eosinophilic immunopathologyArticle Published on 2022-09-292022-11-15 Journal: Vaccine [Category] SARS, 변종, 진단, [키워드] acute respiratory syndrome Adaptive immune response addition antibodies antibody Beta Cell coronavirus coronavirus disease COVID-19 COVID-19 vaccines CpG cross-protective develop feature Gamma IgA antibody IgG antibody immunopathology Infection initial intranasal intranasal vaccination intranasally investigated less lung Lung eosinophilic immunopathology Lymph node mice mucosa nasal nasal mucosa oligonucleotides pandemic potential risk Prevent Protective protective effect reducing Respiratory disease risk SARS-CoV-2 SARS-CoV-2 variant secretory secretory IgA secretory IgA antibody. serum spike-specific IgG subcutaneous vaccination subcutaneously T helper Th1 Th2 Trimeric spike protein upper respiratory tract vaccination Vaccine variant variants viral challenge virus infection viruses [DOI] 10.1016/j.vaccine.2022.08.049 PMC 바로가기