Exploring Therapeutic Advances: A Comprehensive Review of Intestinal Microbiota ModulatorsReview Published on 2024-08-012024-09-05 Journal: Antibiotics [Category] update2024, [키워드] Dysbiosis gut modulation new microbiome-modifying probiotics and prebiotics therapeutic interventions [DOI] 10.3390/antibiotics13080720 PMC 바로가기 [Article Type] Review
Metabolism Pathways of Major Therapeutics for Treating Monkeypox Mono- and Co-infection with Human Immunodeficient Virus or SARS-CoV-2Article Published on 2024-05-062024-09-05 Journal: Current drug metabolism [Category] update2024, [키워드] Coinfection HIV Monkeypox Monoinfection SARS-CoV-2 therapeutic interventions [DOI] 10.2174/1389200224666230607124102 PMC 바로가기 [Article Type] Article
Navigating the Cytokine Storm: A Comprehensive Review of Chemokines and Cytokines in SepsisInternal Medicine Published on 2024-02-152024-09-05 Journal: Cureus [Category] update2024, [키워드] Biomarkers chemokines Cytokine storm immune response Sepsis therapeutic interventions [DOI] 10.7759/cureus.54275 PMC 바로가기 [Article Type] Internal Medicine
Exploring Immunome and Microbiome Interplay in Reproductive Health: Current Knowledge, Challenges, and Novel Diagnostic ToolsMicrobiome in Reproduction Published on 2024-01-232024-09-05 Journal: Studies in Family Planning [Category] update2024, [키워드] diagnostic tools Immunome interactions microbial flow cytometry Microbiome Next-generation sequencing phage immunoprecipitation sequencing reproductive health therapeutic interventions [DOI] 10.1055/s-0043-1778017 PMC 바로가기 [Article Type] Microbiome in Reproduction
“There is no one who helps you with it”: experiences of people with long COVID regarding medical care, therapeutic measures, and barriers in the German healthcare system: results of a qualitative study with four focus groupsarticle Published on 2023-10-262024-09-05 Journal: BMC Health Services Research [Category] update2024, [키워드] Barriers to care COVID-19 Focus groups Germany Healthcare system Long COVID Medical care qualitative study SARS-CoV-2 therapeutic interventions [DOI] 10.1186/s12913-023-10170-x PMC 바로가기 [Article Type] article
An outlook on potential protein targets of COVID-19 as a druggable siteArticle Published on 2022-11-012022-11-15 Journal: Molecular biology reports [Category] COVID19(2023년), SARS, 변종, 치료제, [키워드] approved cause claimed clinical trial combating contagious COVID-19 COVID-19 disease Cryo-electron microscopy Delta Efficacy feature genomic help host cell host protein infecting inhibit mechanism of action MERS-CoV Mutation non-structural proteins omicron pandemic Protein Protein target proteolytic cleavage raised Repurposed drug required SARS-CoV SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 protein shown similarity spike Spike protein strain suggested the vaccine therapeutic drugs therapeutic interventions Vaccines variants of SARS-CoV-2 viral infection virus Wuhan X-ray diffraction [DOI] 10.1007/s11033-022-07724-3 PMC 바로가기
Griseofulvin: An Updated Overview of Old and Current KnowledgeArticle Published on 2022-10-182022-11-16 Journal: Molecules [Category] COVID19(2023년), SARS, 신약개발, 유전자 메커니즘, [키워드] ACE2 addition ascomycetes binding cancer cell capillary blood flow Cell contribute current derivative dermatophytic fungi disrupt domain Drug repurposing ENhance explain FDA-approved drug filament protein griseofulvin griseofulvin derivatives gsf gene cluster Hepatitis hepatitis C virus hepatocyte IMPROVE infections information inhibitory effect Inhibitory effects Interaction introduced K18 Liver injury Mallory mechanism metabolite metabolites mitosis molecular docking analysis multifunctional polyketide compound produced RBD RdRP Replication responsible RNA-dependent RNA polymerase rodent SARS-CoV-2 SARS-CoV-2 entry SARS-CoV-2 main protease severity Spike protein spindle microtubule. therapeutic interventions treated Vascular viral replication [DOI] 10.3390/molecules27207034 PMC 바로가기
SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 proteinArticle Published on 2022-09-122022-11-15 Journal: PLoS Pathogens [Category] SARS, 치료제, [키워드] activities antiviral response binding catalytic domain Cell cellular metabolism complexes conserved Critical enzyme exhibit experiments expressed form group inhibitor Innate immunity interact Interaction investigated knock-out lysine marker MAVS mounted non-structural protein Protein reduced residues SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral SIRT5 stable complex therapeutic interventions Treatment viral replication [DOI] 10.1371/journal.ppat.1010811 PMC 바로가기
Exploring the Impact of ACE Inhibition in Immunity and Disease면역 및 질병에 대한 ACE 억제의 영향 탐색Review Published on 2022-08-042022-09-11 Journal: Journal of the Renin-Angiotensin-Aldosterone Syste [Category] SARS, 치료기술, [키워드] ACE ACE inhibitor ACE inhibitors aldosterone Alter angiotensin Angiotensin II angiotensin receptor blocker Angiotensin receptor blockers Angiotensin-converting enzyme Antibiotic resistance Antigen presentation ARBs Arthritis Autoimmune autoimmune conditions Autoimmune disease Autoimmune diseases benefit Cancer Complication contribute coronavirus Diseases elevated enzyme highlight human neutrophil human neutrophils Immune cell immune cell populations immune cells immune regulation Immunocompromise Impact implicated independent independent of Infection Inflammation inflammatory immune cell inflammatory immune cells inhibition inhibitor Lupus Macrophage macrophages malignancy neurodegenerative Neutrophils no effect outcome overactive overexpression pandemic Patient phagocytosis RAAS Renin renin-angiotensin-aldosterone system Research responses rheumatoid arthritis risk ROS SARS-CoV2 therapeutic interventions understanding wake Zinc [DOI] 10.1155/2022/9028969 PMC 바로가기 [Article Type] Review
Relevance of the post-COVID syndrome within rehabilitation (PoCoRe): study protocol of a multi-centre study with different specialisationsControlled Clinical Trial Published on 2022-07-292022-10-05 Journal: BMC Psychology [Category] COVID19(2023년), SARS, 임상, [키워드] addition Affect affected Anxiety Disorder benefit cardiological Catamnesis clinics cognitive comparison conducted control group Coping strategy Course COVID-19 disease Depression described discharge Dyspnea exercise fatigue functional Germany help impairment implication indication infected with SARS-CoV-2 limitations Measures neurological outpatient clinic Patient physical physical ability Post Exercise Malaise Post-COVID rehabilitation post-COVID-19 patient Probability Psychological psychological testing psychosomatic public health Quality of life receive Registered rehabilitation rehabilitation patient Relevance Seven Somatic Study protocol Symptoms syndrome the patient therapeutic interventions therapy Treatment Treatment effectiveness usual care work Work ability. [DOI] 10.1186/s40359-022-00892-8 PMC 바로가기 [Article Type] Controlled Clinical Trial