Criminal of Adverse Pregnant Outcomes: A Perspective From Thyroid Hormone Disturbance Caused by SARS-CoV-2Cellular and Infection Microbiology Published on 2022-01-032022-10-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] COVID-19, MERS, SARS, [키워드] abnormality acute respiratory syndrome Adverse Adverse pregnancy outcomes coronavirus coronavirus disease COVID-19 death disorder disturbance dysfunction Evidence fetal growth hormone immune response Infection mechanism Mild outcome outcomes Pregnancy pregnant women Preterm birth SARS-CoV-2 shown Surveillance Thyroid thyroid hormone [DOI] 10.3389/fcimb.2021.791654 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Nonthyroidal illness syndrome (NTIS) in severe COVID-19 patients: role of T3 on the Na/K pump gene expression and on hydroelectrolytic equilibrium중증 COVID-19 환자의 비갑상선 질환 증후군(NTIS): Na/K 펌프 유전자 발현 및 가수전해 평형에 대한 T3의 역할Research Published on 2021-12-032022-09-10 Journal: Journal of Translational Medicine [Category] SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] acute phase addition administration Admission affected Analysis analyzed benefit Bioelectrical Impedance Analysis Bioelectrical Impedance Analysis, BIA Body body composition coding Combination condition conditions correlated correlation Course COVID-19 COVID-19 patient COVID-19 patients Critical Critically ill demonstrated develop disease dose-dependent manner Effect Endpoint evaluate evaluated exhibited expression extracellular water fraction functional Gene Expression highest hormone Hospitalized Hydration Hypothyroid ICU illness illnesses increase in Indicator intensive care intensive care unit intracellular water inverse correlation involved isoform lowest mammals mass mechanism mononuclear cell mRNA mRNA expression myxedema Na+/K+ pump gene nonthyroidal illness syndrome Nonthyroidal Illness Syndrome, NTIS occur outpatients parameter Pathogenesis Patient patients PBMC performed Peripheral blood Peripheral blood mononuclear cells Potassium pump reduction retrieved Rome salt serum severe COVID-19 severity similarity sodium Sodium/potassium exchangeable ratio stimulate syndrome the disease the patient these cell These cells Thyroid Thyroid diseases thyroid function thyroid hormone Thyroid hormones Total total body total body water Transcriptome transcriptome analysis treated Treatment trials university water [DOI] 10.1186/s12967-021-03163-z PMC 바로가기 [Article Type] Research
Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients2019년 한국인 환자의 갑상선 호르몬 프로필과 코로나바이러스 질병에 대한 예후적 영향Observational Study Published on 2021-08-012022-09-11 Journal: Endocrinology and metabolism (Seoul, Korea) [Category] MERS, 바이오마커, 임상, [키워드] 95% confidence interval Admission analyzed association change clinical Clinical data clinical outcomes coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients Critical disease death Decreased disease disease severity dysfunction euthyroid Euthyroid sick syndromes evaluate evaluated followed by hazard ratio highest hormone Hormones Impact intensive care intensive care unit admission Korean lowest marker mechanical ventilation middle Mortality outcome Patient patients patients with COVID-19 profile Prognosis prognostic reported serum sick significantly lower South Korea suppression suppression of thyroid function syndrome Thyroid thyroid dysfunction thyroid function thyroid hormone Thyroid hormones thyroid stimulating hormone thyrotoxicosis triiodothyronine Triiodothyronine. TSH [DOI] 10.3803/EnM.2021.1109 PMC 바로가기 [Article Type] Observational Study
Network analysis and molecular mapping for SARS-CoV-2 to reveal drug targets and repurposing of clinically developed drugsSARS-CoV-2에 대한 네트워크 분석 및 분자 매핑을 통해 약물 표적을 밝히고 임상적으로 개발된 약물의 용도 변경Article Published on 2021-03-012022-08-31 Journal: Virology [Category] MERS, SARS, 신약개발, 유전자 메커니즘, 치료제, [키워드] (hydroxychloroquine) Analysis Antibiotics antimalarial antiretroviral Azithromycin BCL-2 biological process carried chemokine Chemokine receptor clinically Combination coronavirus dietary supplement dietary supplements disease networks docking docking analysis docking study drug drug combination Drug repurposing drug target effective EGFR ErbB Estrogen event FoxO global pandemic GnRH HIF-1 host inflammatory response Hydroxychloroquine IL-17 insulin Interaction involved Jak-STAT KEGG pathway analysis life cycle Lopinavir LOPINAVIR AND RITONAVIR MAPK modulation molecular molecular docking molecular mechanism morbidity and mortality mortality rate multiple pathway multiple pathways network Neurotrophin novel Novel coronavirus Ontology PARP pathway platelet activation predict PRKCB Process analysis receptor reduce Ritonavir SARS-CoV-2 SARS–CoV–2. signaling pathway STAT suggested target targets thyroid hormone TNF Toll-like receptor Treatment VEGF Viral viral infection viral infectivity viral life cycle viral replication virus Vitamin Vitamin C [DOI] 10.1016/j.virol.2020.12.006 PMC 바로가기 [Article Type] Article
Commentary: Euthyroid Sick Syndrome in Patients With COVID-19Endocrinology Published on 2021-02-102022-10-31 Journal: Frontiers in Endocrinology [Category] Coronavirus, MERS, [키워드] Anosmia COVID-19 COVID-19 pandemic sarcopenia Thyroid diseases thyroid hormone thyromimetics [DOI] 10.3389/fendo.2021.633097 PMC 바로가기 [Article Type] Endocrinology
Best Achievements in Clinical Thyroidology in 20202020년 임상 갑상선학에서 최고의 성과Review Published on 2021-02-012022-09-12 Journal: Endocrinology and metabolism (Seoul, Korea) [Category] MERS, 진단, [키워드] achievement Cancer clinical conducted coronavirus disease COVID-19 diagnostic diagnostics disease dysfunction highlight molecular Molecular diagnostic techniques Neoplasms pandemic era Research risk Therapeutics Thyroid Thyroid diseases thyroid hormone Thyroid neoplasms. [DOI] 10.3803/EnM.2021.103 PMC 바로가기 [Article Type] Review
Thyroid dysfunction may be associated with poor outcomes in patients with COVID-19Research article Published on 2021-02-012022-10-05 Journal: Molecular and cellular endocrinology [Category] 바이오마커, [키워드] activated analyzed Aspartate transaminase association Biomarker C-reactive protein carried Clinical features collected COVID-19 COVID-19 patient Critical defined develop disease dysfunction enrolled eosinophil euthyroid sick Fatality rate hospital Hospitalization Hospitalized Hypothyroidism immune system Inflammatory response Injury lactate dehydrogenase longitudinal analysis lymphocyte metabolism modulating morbidity and mortality neutrophil count outcome Patient patients with COVID-19 Platelet preliminary finding Prevalence procalcitonin Prognosis Result SARS-CoV-2 serum serum biomarker significantly higher Subclinical hypothyroidism syndrome the disease Thyroid thyroid dysfunction thyroid function thyroid hormone thyrotoxicosis Treatment strategies troponin I Union Hospital West with COVID-19 Wuhan, China [DOI] 10.1016/j.mce.2020.111097 [Article Type] Research article
Predictors of inflammatory activity in treatment-naive hepatitis B e-antigen-negative patients with chronic hepatitis B infectionArticle Published on 2020-11-012023-06-12 Journal: The Journal of international medical research [Category] B형 간염, [키워드] Chronic Hepatitis B HBeAg-negative inflammatory activity noninvasive biomarkers thyroid hormone total triiodothyronine. [DOI] 10.1177/0300060520969582 PMC 바로가기
Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trialCOVID-19 감염이 있는 중환자 치료를 위한 Triiodothyronine: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2020-06-262022-08-13 Journal: Trials [Category] SARS, 임상, [키워드] (therapeutic dose) 1:1 48 hour 48 hours Acute myocardial infarction addition Administered administration adopted allocation sequence Alpha Analysis blinded Blinding Caregivers clinical evidence collected comparator conserved copy Corticosteroid COVID-19 COVID-19 infected patient COVID-19 infection CRF criterion Critical Critical illness Critically ill Critically ill patient critically ill patients database defined detect Device diagnosed dissemination dosage dose double-blind drug Drug administration ECMO effective Efficacy and safety element enrolled Estimated EudraCT excluded extubation favorable effect female patient Final final analysis Follow-up followed by Germany Greece group hypoxia hypoxic condition hypoxic conditions ICU Identifier Ill illness immune system include increased mortality indicate information infusion initiation of treatment injection intensive care unit interim analysis investigator IWRS less Life expectancy maintenance dose MAPK mechanical respiratory mechanical ventilation multi-organ dysfunction number objective outcome participant Patient performed pharmacological treatment Placebo placebo controlled trial Pregnancy Primary outcome protocol Pulmonary infection randomisation randomised randomised controlled trial randomization Randomized recruited recruitment reveal Sample size Sepsis severe systemic disease signaling pathways solution Sponsor status study groups Study protocol subject Support systemic disease therapeutic therapeutic dose Thyroid thyroid hormone tissue trauma Treatment treatment allocation Trial Trial registration triiodothyronine unblinding university university hospital ventilatory support Version Viral viral infection Viral load website with COVID-19 [DOI] 10.1186/s13063-020-04474-0 PMC 바로가기 [Article Type] Letter
TUG1 Is a Regulator of AFP and Serves as Prognostic Marker in Non-Hepatitis B Non-Hepatitis C Hepatocellular Carcinoma †Article Published on 2020-01-212023-06-03 Journal: Cells [Category] B형 간염, Fulltext, [키워드] Alpha-Fetoprotein long non-coding RNA overall survival Prognostic marker thyroid hormone [DOI] 10.3390/cells9020262 PMC 바로가기 [Article Type] Article