Genetic variation of TLR3 gene is associated with the outcome of hepatitis b infection in mauritanian patients: case control studyResearch Published on 2024-06-212024-09-05 Journal: BMC Infectious Diseases [Category] update2024, [키워드] Chronic hepatitis B virus single-nucleotide polymorphism TLR3 TLR4 [DOI] 10.1186/s12879-024-09503-w PMC 바로가기 [Article Type] Research
NLRC5 senses NAD + depletion to form a PANoptosome driving PANoptosis and inflammationArticle Published on 2024-06-122024-09-05 Journal: Cell [Category] update2024, [키워드] Apoptosis ASC caspase caspase-1 caspase-3 caspase-7 caspase-8 Colitis creatinine DAMP DSS gasdermin D gasdermin E heme Hemolysis hemophagocytic lymphohistiocytosis Inflammasome Inflammation Inflammatory cell death LPS MLKL necroptosis nicotinamide adenine dinucleotide NLRC5 NLRP12 NLRP3 Pam3CSK4 PAMP PANoptosis PANoptosome Phenylhydrazine poly(I:C) pyroptosis RIPK3 ROS TLR2 TLR4 TLRs TNF [DOI] 10.1016/j.cell.2024.05.034 PMC 바로가기 [Article Type] Article
Deciphering the therapeutic potential of trimetazidine in rheumatoid arthritis via targeting mi-RNA128a, TLR4 signaling pathway, and adenosine-induced FADD-microvesicular shedding: In vivo and in silico studyPharmacology Original Research Published on 2024-06-112024-09-05 Journal: Frontiers in Pharmacology [Category] update2024, [키워드] adenosine level FADD-microvesicular shedding histopathological analysis immunological and inflammatory markers mi-RNA128a rheumatoid arthritis TLR4 Trimetazidine [DOI] 10.3389/fphar.2024.1406939 PMC 바로가기 [Article Type] Pharmacology Original Research
Diverse roles of SARS-CoV-2 Spike and Nucleocapsid proteins in EndMT stimulation through the TGF-β-MRTF axis inhibited by aspirinResearch Published on 2024-05-282024-09-05 Journal: Cell Communication and Signaling : CCS [Category] update2024, [키워드] ACE2 Aspirin EndMT fibrosis MRTFs SARS-CoV-2 TGF-β TLR4 [DOI] 10.1186/s12964-024-01665-z PMC 바로가기 [Article Type] Research
The critical role of toll-like receptor 4 in bone remodeling of osteoporosis: from inflammation recognition to immunityImmunology Review Published on 2024-03-052024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] mechanism Osteoblast Osteoclasts Osteoporosis TLR4 Treatment [DOI] 10.3389/fimmu.2024.1333086 PMC 바로가기 [Article Type] Immunology Review
The single nucleotide polymorphism rs4986790 (c.896A>G) in the gene TLR4 as a protective factor in corona virus disease 2019 (COVID-19)Immunology Original Research Published on 2024-02-162024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] COVID-19 disease severity IL-6 polymorphism Prognostic marker rs4986790 SARS-CoV-2 TLR4 [DOI] 10.3389/fimmu.2024.1355193 PMC 바로가기 [Article Type] Immunology Original Research
Co-Delivery of Novel Synthetic TLR4 and TLR7/8 Ligands Adsorbed to Aluminum Salts Promotes Th1-Mediated Immunity against Poorly Immunogenic SARS-CoV-2 RBDArticle Published on 2023-12-232024-09-05 Journal: Vaccines [Category] update2024, [키워드] adju-phos adjuvants Alhydrogel COVID-19 SARS-CoV-2 TLR4 TLR7/8 toll-like receptor (TLR) agonist [DOI] 10.3390/vaccines12010021 PMC 바로가기 [Article Type] Article
Genetic and immunological insights into COVID-19 with acute myocardial infarction: integrated analysis of mendelian randomization, transcriptomics, and clinical samplesImmunology Published on 2023-11-062024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] ABCA1 Acute myocardial infarction causal relationship COVID-19 immune dysregulation TLR4 [DOI] 10.3389/fimmu.2023.1286087 PMC 바로가기 [Article Type] Immunology
Emulsion and liposome-based adjuvanted R21 vaccine formulations mediate protection against malaria through distinct immune mechanisms에멀젼 및 리포솜 기반 보조제 R21 백신 제제는 뚜렷한 면역 메커니즘을 통해 말라리아에 대한 보호를 중재합니다.Article Published on 2023-10-312024-07-29 Journal: Cell Reports Medicine [Category] 말라리아, [키워드] adjuvants emulsions Inflammasome liposomes malaria NLRP3 QS-21 Saponin TLR4 Vaccines [DOI] 10.1016/j.xcrm.2023.101245 PMC 바로가기
An immunoinformatics approach to epitope-based vaccine design against PspA in Streptococcus pneumoniaearticle Published on 2023-05-112024-09-05 Journal: Journal of Genetic Engineering & Biotechnology [Category] update2024, [키워드] CTL HTL LBL pneumococcal surface protein A (PspA) SPN TLR4 [DOI] 10.1186/s43141-023-00506-9 PMC 바로가기 [Article Type] article