TLR7 enhancing follicular helper T (Tfh) cells response in C57BL/6 mice infected with Plasmodium yoelii NSM TLR7 mediated Tfh cells in P. yoelii infected micearticle Published on 2024-03-312024-09-01 Journal: Immunology [Category] 말라리아, [키워드] Ikzf2 Plasmodium STAT3 T follicular helper cells TLR7 [Article Type] article
Inhibitory receptors of plasmacytoid dendritic cells as possible targets for checkpoint blockade in cancerImmunology Review Published on 2024-03-052024-09-05 Journal: Frontiers in immunology [Category] update2024, [키워드] BDCA-2 C-type lectin receptor checkpoint inhibitors ILT7 Interferon alpha pDC exhaustion TLR7 [DOI] 10.3389/fimmu.2024.1360291 PMC 바로가기 [Article Type] Immunology Review
Revealing the roles of TLR7, a nucleic acid sensor for COVID-19 in pan-cancerArticle Published on 2023-05-092024-09-05 Journal: Biosafety and Health [Category] update2024, [키워드] COVID-19 Pan-cancer Prognosis SARS-CoV-2 TLR7 [DOI] 10.1016/j.bsheal.2023.05.004 PMC 바로가기 [Article Type] Article
TLR7 modulates extramedullary splenic erythropoiesis in P. yoelii NSM-infected mice through the regulation of iron metabolism of macrophages with IFN-γarticle Published on 2023-04-302024-09-01 Journal: Frontiers in immunology [Category] 말라리아, [키워드] extramedullary splenic erythropoiesis IFN-γ Iron metabolism macrophages malaria TLR7 [Article Type] article
TLR7 Activation in M-CSF-Dependent Monocyte-Derived Human Macrophages Potentiates Inflammatory Responses and Prompts Neutrophil RecruitmentResearch Article Published on 2023-04-112024-09-05 Journal: Journal of innate immunity [Category] update2024, [키워드] Inflammatory responses macrophages Neutrophil-attracting chemokines TLR7 [DOI] 10.1159/000530249 PMC 바로가기 [Article Type] Research Article
Immunological and translational key challenges in systemic lupus erythematosus: A symposium updateResearch paper Published on 2023-03-312024-09-04 Journal: Journal of Translational Autoimmunity [Category] 대상포진, [키워드] COVID-19 genetics lupus nephritis Lupuzor nervous system Platelets systemic lupus erythematosus TLR7 Vaccine [DOI] 10.1016/j.jtauto.2023.100199 PMC 바로가기 [Article Type] Research paper
Sex-biased expression of the TLR7 gene in severe COVID-19 patients: Insights from transcriptomics and epigenomicsArticle Published on 2022-12-012022-11-16 Journal: Environmental research [Category] 유전자 메커니즘, [키워드] acute phase analyzed Blood Cohort coronavirus disease COVID-19 COVID-19 patient CpG DNA DNA methylation dose downregulated embryogenesis epidemiological data epigenomic epigenomics Evidence expression female females gene product Genetic variation Genome-wide association studies Host inactivation incidence incidence of COVID-19 independent insight long-COVID-19 male males Methylation n-Counter. nasal patients Post-infection RNAseq Saliva Severe case severe COVID-19 severity Sex significantly higher stratified suggested timepoint TLR7 TLR7 gene transcriptomics with COVID-19 [DOI] 10.1016/j.envres.2022.114288 PMC 바로가기
Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics InitiativeArticle Published on 2022-11-032022-11-15 Journal: PLoS Genetics [Category] SARS, 변종, 진단, [키워드] Analysis association chromosome Cohort controls country COVID-19 Deleterious disease expected Genetic genetics Genome-wide association study identify increase in initiative loci outcome outcomes Pathogenesis performed rare variant Result severe disease Support susceptibility the SARS-CoV-2 TLR7 Toll-like receptor variant whole-genome sequencing with COVID-19 [DOI] 10.1371/journal.pgen.1010367 PMC 바로가기
Nucleic acid-sensing toll-like receptors: Important players in Sjögren’s syndromeReview Published on 2022-10-312023-07-10 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] Autoimmunity COVID-19 nucleic acid-sensing TLRs Sjögren’s syndrome systemic lupus erythematosus TLR7 TLR8 TLR9 [DOI] 10.3389/fimmu.2022.980400 PMC 바로가기 [Article Type] Review
Artificial Neural Network-Based Study Predicts GS-441524 as a Potential Inhibitor of SARS-CoV-2 Activator Protein Furin: a Polypharmacology ApproachArticle Published on 2022-10-012022-11-15 Journal: Applied biochemistry and biotechnology [Category] COVID19(2023년), SARS, 신약개발, 치료제, [키워드] activator ANN Antiviral antiviral drug antivirals artificial Bacterial Bacterial infection Cancer caused Compound COVID-19 diabetes DNA drug Drug repurposing ENhance FCGR1A FDA furin furin cleavage site Grazoprevir GS-441524 help human protein inhibit inhibiting inhibitor inhibitors LB-VS LDLR mammalian MK-5172 network pharmacology Neural Neurological disorders pandemic Patient PCK1 PNP polybasic Polypharmacology Potential researcher SARS-CoV-2 SB-VS searched SOM. substrate target the spike protein TLR7 turn Virtual screening virus [DOI] 10.1007/s12010-022-03928-2 PMC 바로가기