Transcriptional regulation of TacL-mediated lipoteichoic acids biosynthesis by ComE during competence impacts pneumococcal transformationarticle Published on 2024-05-082024-09-05 Journal: Frontiers in Cellular and Infection Microbiology [Category] update2024, [키워드] ComE competence Streptococcus pneumoniae teichoic acids transcriptional regulation transformation [DOI] 10.3389/fcimb.2024.1375312 PMC 바로가기 [Article Type] article
Magnetic bead-based separation of pneumococcal serotypes폐렴구균 혈청형의 자기 비드 기반 분리Article Published on 2023-02-212024-08-24 Journal: Cell Rep Methods [Category] 폐렴구균 감염증, [키워드] capsular polysaccharide capsule switch pneumococcus Saliva serotypes Streptococcus pneumoniae transformation
Impact of hypertension on long-term humoral and cellular response to SARS-CoV-2 infectionArticle Published on 2022-09-022022-11-15 Journal: Frontiers in Immunology [Category] SARS, 진단, 치료기술, 치료제, [키워드] age airway analyzed Anosmia association Asthma Blood blood collection BMI cellular Cellular immune response cellular response clinical factor confounding factor confounding factors COPD COVID COVID - 19 determine develop diabetes exacerbate HCW HCWs Health care Hospitalized humoral humoral and cellular response hyperinflammation hypertension hypertensive identify immune response Impact independent Infection less median multivariate regression analysis myalgia Neutralizing antibodies normotensive outbreak PCR positivity regression analysis respiratory tract response Risk factors S1 IgG SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection Sex shown significantly smoking T cell Test transformation viral clearance was done [DOI] 10.3389/fimmu.2022.915001 PMC 바로가기
SARS-CoV-2 Achieves Immune Escape by Destroying Mitochondrial Quality: Comprehensive Analysis of the Cellular Landscapes of Lung and Blood Specimens From Patients With COVID-19SARS-CoV-2, 미토콘드리아 품질을 파괴하여 면역 탈출 달성: COVID-19 환자의 폐 및 혈액 표본의 세포 환경에 대한 종합 분석Article Published on 2022-07-012022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), SARS, 치료제, [키워드] activated activating alveolar alveolar epithelial cell alveolar epithelial cells alveolar macrophage Alveolar macrophages analyzed antiviral immunity B cell B cells blocked Blood calcium cell count Comprehensive coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients crossfire cytokine Cytokine storm dataset Defense Degradation energy metabolism epithelial epithelial cell epithelial cells escape exacerbated excessive inflammation explain expression Gene Expression HIF1a Host IFI27 immune immune cells Immune escape Inflammation inhibited Interaction interferon landscape lung tissue Lungs Macrophage macrophages manifestation MCU metabolic pathway metabolism Mitochondria mitochondrial mitochondrial fission mitochondrial functions mitochondrial quality. pathway patients with COVID-19 Perspective plasma pro-inflammatory Regulatory T cell regulatory T cells released Replication respiratory capacity resulting RNA-sequencing SARS-CoV-2 significant changes in Single-cell RNA-sequencing T cells target transformation Tregs type I viral infection [DOI] 10.3389/fimmu.2022.946731 PMC 바로가기 [Article Type] Article
Innovations in Medical Education During the COVID-19 Era and Beyond: Medical Students’ Perspectives on the Transformation of Real Public Health Visits Into Virtual FormatCOVID-19 시대와 그 이후의 의학 교육 혁신: 실제 공중 보건 방문을 가상 형식으로 변환하는 의대생의 관점Article Published on 2022-06-132022-09-11 Journal: Frontiers in Public Health [Category] COVID19(2023년), SARS, 치료기술, [키워드] activity addition Bahrain categorical data chi-square test college communicable disease communicable diseases components Control COVID-19 COVID-19 pandemic Digital education feedback female field visits food safety form format Gulf Innovation lectures male Medical Science Medical Sciences Medicine no significant difference no significant differences P -value Pearson Pearson chi-square test Program provided Public public health Public Health Program response responses Satisfaction significantly higher statistically significant statistically significant difference student submitted t -test the mean total sample size transformation university Virtual was used [DOI] 10.3389/fpubh.2022.883003 PMC 바로가기 [Article Type] Article
Potential of Ferritin-Based Platforms for Tumor Immunotherapy종양 면역 요법을 위한 페리틴 기반 플랫폼의 잠재력Review Published on 2022-04-222022-09-11 Journal: Molecules [Category] COVID19(2023년), SARS, 변종, [키워드] addition animal models antioxidant cellular clinical trials coronavirus dendritic dendritic cells described draining lymph nodes drug drugs Efficacy encapsulate expected ferritin fibroblasts functions greater immune immunomodulator Immunotherapy iron iron homeostasis Lymph node M2 tumor-associated macrophages macrophages mechanism Modification On the Road overcome penetration Phase I platform Potential PROTECT Protein Research road subunits tissue transformation Tumor tumor cells Tumor vaccine tumor-associated fibroblasts. tumor-associated macrophages unique Vaccine variants of SARS-CoV-2 [DOI] 10.3390/molecules27092716 PMC 바로가기 [Article Type] Review
Harmonized D-dimer levels upon admission for prognosis of COVID-19 severity: Results from a Spanish multicenter registry (BIOCOVID-Spain study)COVID-19 심각도의 예후를 위해 입원 시 조화된 D-dimer 수준: 스페인 다기관 등록의 결과(BIOCOVID-스페인 연구)Multicenter Study Published on 2022-01-012022-09-11 Journal: Journal of Thrombosis and Thrombolysis [Category] 바이오마커, [키워드] adjusted hazard ratio Admission an area Analysis approach assays association characteristic Clinical practice Coagulopathy comparability COVID-19 COVID-19 patients Cox regression analysis cut-off value D-dimer D-dimer level D-dimer levels death defined dimer Endpoint FEU greater harmonization hospital mortality rate in-hospital mortality in-hospital mortality rate independent Mortality mortality rate multicenter patients Prognosis prognostic receiver operating characteristic regression line reported Result Retrospective multicenter study risk severity Spanish study population test results transformation translate was performed [DOI] 10.1007/s11239-021-02527-y PMC 바로가기 [Article Type] Multicenter Study
Transformation to telephonic genetic counselling during SARS-CoV-2 pandemic: challenges and suggested protocol in Indian scenarioSARS-CoV-2 대유행 중 전화 유전 상담으로의 전환: 인도 시나리오의 과제 및 제안 프로토콜Article Published on 2022-01-012022-09-11 Journal: Journal of genetics [Category] SARS, 유전자 메커니즘, [키워드] Abnormalities COVID-19 COVID-19 pandemic diagnosed gcs Genetic genetic counselling lack lockdown Mumbai offered Patient physical platform precluded protocol public transport recommendation restriction retrospective retrospective data SARS-CoV-2 social distancing suggested their family member their family members transformation Transport wake [DOI] 10.1007/s12041-022-01370-1 PMC 바로가기 [Article Type] Article
Perception of the COVID-19 Pandemic Among Members of Saudi Society: Solidarity, Humility, and ConnectivityFamily/General Practice Published on 2021-11-102022-10-31 Journal: Cureus [Category] COVID-19, [키워드] addressed affected assumed Community community connectivity community perception conducted connectivity coronavirus disease country COVID-19 COVID-19 pandemic cross-sectional develop Epidemics Government handwashing healthcare Healthcare system Humility immune indicated Kingdom magnitude majority Masks member Ministry of Health MoH outlined pandemic participant Participants Perception precautionary measures preventative measure Program questionnaire Result sneezing etiquette social distancing solidarity transformation vision wearing gloves [DOI] 10.7759/cureus.19427 PMC 바로가기 [Article Type] Family/General Practice
Occurrence, Fate, Effects, and Risks of Dexamethasone: Ecological Implications Post-COVID-19Review Published on 2021-10-272022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] Administered anti-inflammatory drug Aquatic ecosystems cause concentrations contaminant coronavirus disease COVID-19 crustacean Deleterious demonstrated Dexa Dexamethasone downstream drinking water drug ecological ecological implication Effect Effects fish glucocorticoid hospitalizations hospitalized COVID-19 patients implication IMPROVE infections management molecular Occurrence organism outbreak outcome plants raised reduction released SARS-CoV-2 Surface water susceptible transformation treat Treatment wastewater whole organism widespread [DOI] 10.3390/ijerph182111291 PMC 바로가기 [Article Type] Review