Evaluation of the impact of pre-analytical conditions on sample stability for the detection of SARS-CoV-2 RNAArticle Published on 2022-11-012022-11-15 Journal: Journal of virological methods [Category] SARS, 치료기술, 치료제, [키워드] collected Community condition conditions cycle threshold Demand Diagnosis diagnostics False negative increase in independent Laboratory MOST PBS postal service provide RNA RNA extraction RT-qPCR Sample Sample stability. SARS-CoV-2 SARS-CoV-2 E gene SARS-CoV-2 RNA sensitivity stability Swab temperature tested Transport media transported Variation Viral load VTM [DOI] 10.1016/j.jviromet.2022.114607 PMC 바로가기
Local monitoring of SARS-CoV-2 variants in two large California counties in 2021Article Published on 2022-10-112022-11-16 Journal: Scientific Reports [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome Advarra Alpha variant analyzed approved carried caused changed changes in Cohort conducted confidence interval coronavirus COVID-19 Cycle threshold value Delta delta variant effort enrolled Enrollment Epidemiology genomic data Hispanic identify individual institutional review board Laboratory less Los Angele MONITOR Mutation nare nasal offered Older over participant Participants PCR polymerase chain positive Positive test Prevalence proportion public health resulting Sample SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 strain SARS-CoV-2 testing SARS-CoV-2 variant Sequencing sequencing data Spanish specimen specimens statistical study enrollment study period Surveillance swab specimen Symptom tested transported variant variants of concern women [DOI] 10.1038/s41598-022-21481-0 PMC 바로가기
Performance of nasopharyngeal swab and saliva in detecting Delta and Omicron SARS-CoV-2 variantsDelta 및 Omicron SARS-CoV-2 변이체 검출 시 비인두 면봉 및 타액의 성능Article Published on 2022-10-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus analyzed Chain Reaction characterized conducted coronavirus cough COVID-19 Delta diagnostic Dyspnea epidemic wave epidemic waves expressed highest increase in Infection Laboratory log molecular nasopharyngeal Nasopharyngeal swab no significant difference not significant NP swab NP swabs NPs nucleic acids omicron participant Participants Patient performance polymerase chain polymerase chain reaction processing prospective cohort study real-time RT-PCR reported required respiratory rhinorrhea RNA Saliva saliva samples Sample SARS-CoV-2 SARS-CoV-2 diagnostics SARS-CoV-2 epidemic SARS-CoV-2 variant significant difference sore sore throat specimen specimen collection statistically Symptom Symptoms thawing the mean transported Viral Viral load [DOI] 10.1002/jmv.27898 PMC 바로가기 [Article Type] Article
SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19Article Published on 2022-09-072022-10-06 Journal: EMBO Molecular Medicine [Category] COVID19(2023년), SARS, 진단, [키워드] ACE2 ACE2 protein cells contribute correlated COVID-19 COVID-19 cohort Degradation E3 ligase ENhance entry receptor epithelial epithelial cell epithelial cells Exosome Exosomes humanized Infection Live virus lysine MAP4K3/GLK mice overexpression pathogenesis of COVID-19 patients phosphorylated prevented pseudovirus infection residue RNA-sequencing SARS-CoV-2 SARS-CoV-2 pseudovirus SARS-CoV-2 spike SARS-CoV-2 spike protein secretion Serine serum exosome severity stability the SARS-CoV-2 transported UBR4 UBR4. Vesicle with COVID-19 [DOI] 10.15252/emmm.202215904 PMC 바로가기 [Article Type] Article
Is cancer significant comorbid condition in COVID 19 infected patients? -A retrospective analysis experienced in a tertiary care center in Eastern IndiaResearch article Published on 2022-09-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 바이오마커, 변종, 유전자 메커니즘, 진단, 치료기술, [키워드] active cancer Admission age analyzed asymptomatic patient Cancer cancer centre cancer stage Care cohort study Comorbidity Complete correlated COVID COVID 19 COVID 19 patient COVID 19 patients died disease female female patient finding Gender Government hospital Hospitalization ICU India Low income group males Malnutrition MOST Patient patients patients died positive Research Retrospective analysis RT PCR RT-PCR Stress symptomatic tested the patient therapeutic thought transferred transported Treatment virus was used [DOI] 10.1016/j.amsu.2022.104248 [Article Type] Research article
Environmental contributions to the interactions of COVID-19 and asthma: a secondary publication and updateReview article Published on 2022-09-012022-10-05 Journal: The World Allergy Organization Journal [Category] 바이오마커, 치료기술, [키워드] addition allergens allergic rhinitis allergies association Asthma biological property caused change changed changes in children China conditions coronavirus 2 coronavirus disease COVID-19 COVID-19 pandemic current Diagnosis Effect Evidence explain extension implementation increase in Inflammation Inhaled intensity Interaction Isolation lockdown non-allergic outbreak outcomes pandemic Patient Phenotypes physical provoke reduce reduction respiratory risk risk factor SARS-CoV-2 severe COVID-19 severe disease Spread transmission rate transported triggered Type variable with COVID-19 worsening Wuhan [DOI] 10.1016/j.waojou.2022.100686 [Article Type] Review article
Avoiding False-Positive SARS-CoV-2 Rapid Antigen Test Results with Point-of-Care Molecular Testing on Residual Test BufferArticle Published on 2022-08-312022-11-15 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] Abbott Ag-RDT Ag-RDTs Analytical specificity Antigen approach assays Asymptomatic Avoiding buffer characterized collected Community coronavirus disease COVID-19 COVID-19 pandemic Disease prevalence evaluated False-positive false-positive result IDNOW individual Laboratory less Local molecular Molecular tests NAAT NAAT assay national guideline nucleic acid amplification occur Organisms PanBio pandemic Patient PCR performed POC point-of-care positive provide Rapid rapid antigen test Rapid diagnostic test Rapid test rapid test results Rapid tests real-time RT-PCR recalled residual response Result RT-PCR SARS-CoV-2 SARS-CoV-2 detection sensitivity specificity specimen subsequent Swab Test Testing transported true positive was performed [DOI] 10.1128/spectrum.00639-22 PMC 바로가기
Anti-SARS-CoV-2 IgM/IgG antibodies detection using a patch sensor containing porous microneedles and a paper-based immunoassay다공성 미세바늘을 포함하는 패치 센서와 종이 기반 면역 분석을 사용한 Anti-SARS-CoV-2 IgM/IgG 항체 검출Article Published on 2022-07-012022-09-11 Journal: Scientific Reports [Category] COVID19(2023년), MERS, SARS, 바이오마커, 유전자 메커니즘, 진단, 치료기술, [키워드] acute respiratory syndrome addition anti-SARS-CoV-2 anti-SARS-CoV-2 IgM antibodies antibody Antibody test Antibody testing antibody tests Biomarkers Blood blood sampling cause complement complementary Concentration coronavirus coronavirus disease Coronavirus disease 2019 Course COVID-19 COVID-19 infection diagnostic tests disease effective expected global pandemic Health Organization identify IgG IgG antibodies IgG antibody IgM IgM/IgG immunoassay immunochromatographic immunochromatographic assay Immunoglobulin Immunoglobulin G immunoglobulin M in vitro infected individual infected individuals Infection Infectious disease Infectious diseases information interstitial fluid invasive limit of detection Mortality New coronavirus outbreak Pain porous Prevent Protein provided puncture site respiratory risk SARS-CoV-2 Severe Acute Respiratory Syndrome Corona Virus specific antibodies specific antibody Spread transported virus WHO widespread World Health Organization Wuhan Wuhan, China [DOI] 10.1038/s41598-022-14725-6 PMC 바로가기 [Article Type] Article
Detection and Stability of SARS-CoV-2 in Three Self-Collected Specimen Types: Flocked Midturbinate Swab (MTS) in Viral Transport Media, Foam MTS, and Saliva자체 수집한 3가지 표본 유형에서 SARS-CoV-2의 검출 및 안정성: 바이러스 수송 배지, 거품 MTS 및 타액의 무리를 이루는 중비갑개 면봉(MTS)Article Published on 2022-06-292022-09-11 Journal: Microbiology Spectrum [Category] COVID19(2023년), SARS, 치료기술, 치료법, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 ambient Analysis children cohorts collected Community Concordance conditions coronavirus COVID-19 detection evaluated exposure to facilitate feasible finding Foam illness illnesses in viral nucleocapsid Open reading frame ORF pandemic positive provided quantification reading respiratory respiratory specimens RT-PCR RT-PCR detection Saliva saliva samples saliva specimen saliva specimens sample collection SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA SARS-CoV-2 testing sensitivity severe acute respiratory syndrome Coronavirus specimen specimen collection spike stability Support Swab temperature tested Transport Transport media transported viral transport media VTM widespread [DOI] 10.1128/spectrum.01033-22 PMC 바로가기 [Article Type] Article
SMART-LAMP: A Smartphone-Operated Handheld Device for Real-Time Colorimetric Point-of-Care Diagnosis of Infectious Diseases via Loop-Mediated Isothermal AmplificationSMART-LAMP: 루프 매개 등온 증폭을 통한 감염성 질병의 실시간 비색 현장 진단을 위한 스마트폰 작동 핸드헬드 장치Article Published on 2022-06-162022-09-12 Journal: Biosensors [Category] MERS, 진단, [키워드] amplification analyzed applied clinical sample Combination COVID-19 COVID-19 patients Device Diagnosis diagnostic diagnostics Diseases feature Infectious disease infectious diseases SARS-CoV-2 isothermal isothermal amplification lack Loop-mediated isothermal amplification mHealth Neglected neglected tropical diseases nucleic acid amplification offer point-of-care point-of-care diagnostics provide Reactions Sensitivity and specificity temperature transported utility [DOI] 10.3390/bios12060424 PMC 바로가기 [Article Type] Article