Treg, regulatory T cells

[키워드] AAK-1, activated protein (AP) 2 associated kinase 1 Ab, antibody ACE, angiotensin-converting enzyme ACEI, ACE inhibitor AEC, alveolar epithelial cells AICD, activation-induced cell death Ang, angiotensin APC, Antigen-Presenting Cell aPTT, activated partial thromboplastin time ARB, Ang II receptor blocker ARDS, acute respiratory distress syndrome AT1R, Ang II receptor type 1 BALF, bronchoalveolar lavage fluid BEC, Bronchial epithelial cell Biomarker BTK, Bruton tyrosine kinase C-GAS-STING, cGAMP binds to stimulator of interferon genes C3 and C5, complement proteins CCL, chemokine (C-C motif) ligand CCR, chemokine (C-C motif) ligand receptor ChiCTR, Chinese Clinical Trial Registry complications COVID-19 COVID-19, coronavirus disease-2019 CP, convalescent plasma CQ, Chloroquine CRP, C-reactive protein CRS, Cytokine release syndrome CT, Computerized Tomography CTL, cytotoxic T lymphocyte CXCL, Chemokine (C-X-C motif) ligand CXCR, chemokine (C-X-C motif) ligand receptor Cytokine storm DIC, disseminated intravascular coagulation dsRNA, double-stranded RNA ESR, Erythrocyte sedimentation rate FcγR, Fc gamma receptor Fio2, fraction of inspired oxygen GAK, G-associated kinase GM-CSF, granulocyte-macrophage colony-stimulating factor GzmB, granzyme B HCQ, hydroxychloroquine HLA, human leukocyte antigen HLH, Hemophagocytic lymphohistiocytosis HR-2, heptad repeat region-2 ICU, admissions to intensive care units IFITM, Interferon-induced transmembrane protein IFN, interferon IL, interleukin immunopathology IP-10, interferon (IFN)-γ inducible protein-10 IRF-1, IFN regulatory factor 1 ISG, induction of IFN-stimulated gene IVIG, intravenous immunoglobulin JAK, Janus kinase JUN, c-Jun N-terminal kinases KL-6, Krebs von den Lungen-6 LAG-3, Lymphocyte-activation gene 3 LDH, lactate dehydrogenase lung LWR, lymphocyte-to-WBCs ratio LY6E, lymphocyte antigen 6 family member E mAb, monoclonal antibody MCP, monocyte chemoattractant protein MDA-5, melanoma differentiation-associated protein-5 MERS, Middle East respiratory syndrome MIP, macrophage inflammatory proteins MOF, Multiple organ failure MUC, mucin N, nucleocapsid nAb, Neutralizing Antibody NCT, clinicaltrials.gov identifier NFkB, nuclear factor kappa-light-chain-enhancer of activated B cells NK, natural killer NKRF, NFkB repressing factor NLR, neutrophil-to-lymphocyte ratio NLRP3, nod-like receptor protein 3 NSP, Non-structural Proteins NTD, N Terminal Domain ORF-1ab, open reading frame 1ab Pao2, partial pressure of oxygen PCT, procalcitonin PD1, programmed cell death protein 1 PKR, protein kinase R PLR, platelet-to-lymphocyte ratios PRR, Pattern Recognition Receptors PT, prothrombin time RA, Rheumatoid arthritis RAS, regulator of the renin-angiotensin system RBD, receptor-binding domain rBP-C33Leu, recombinant surfactant protein C analogue rhACE2-Fc fusion proteins, recombinant human ACE2-Fc fusion proteins rhIL-1ra, recombinant human IL-1 receptor RIG, retinoic acid-inducible gene-I rIL7, recombinant IL-7 RLR, RIG-I-like receptors RT-qPCR, real time-quantitative PCR S-protein, spike-protein S1PR, sphingosine-1-phosphate receptors SAA, serum amyloid A SARS-CoV, severe acute respiratory syndrome coronavirus SARS, severe acute respiratory scFv, single-chain variable fragment siRNA, small interfering RNA SP, surfactant SPo2, arterial oxygen saturation srhACE2, soluble recombinant human (srh)ACE2 ssRNA, single-stranded RNA TGF, Transforming growth factor Th, helper T cell TIM-3, T-cell immunoglobulin mucin 3 TLR, Toll like Receptor TMPRSS2, Transmembrane serine protease 2 TNF-α, tumor necrosis factor Treg, regulatory T cells VEGF, Vascular endothelial growth factor WBC, White blood cell
[DOI] 10.1016/j.cytogfr.2020.10.002 PMC 바로가기 [Article Type] Review