trial sequential analyses – Communicable Diseases Research

Vaccines to prevent COVID-19: A living systematic review with Trial Sequential Analysis and network meta-analysis of randomized clinical trials

COVID-19를 예방하기위한 백신 : 무작위 임상 시험의 시험 순차 분석 및 네트워크 메타 분석을 통한 살아있는 체계적인 검토

Meta-Analysis

Published on 2022-01-212022-09-10
Journal: PLoS ONE [Category] meta-analysis, 임상,

Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines

COVID-19 감염 예방 및 치료를 위한 Ivermectin: 임상 지침을 제공하기 위한 체계적인 검토, 메타 분석 및 시험 순차 분석

Meta-Analysis

Published on 2021-06-212022-09-11
Journal: American journal of therapeutics [Category] SARS, 치료제,

[키워드] 95% confidence interval adverse event Analysis anti-inflammatory properties antiparasitic Antiviral approach Area average average risk benefit certainty Chemoprophylaxis clinical Clinical course clinical trials conducted COVID-19 COVID-19 infection database death Deterioration Efficacy estimate Evidence evidence of guideline high risk Inclusion Ivermectin ivermectin treatment less mechanical ventilation Medicine meta-analyses Meta-analysis Mortality no difference outcome pandemic participant prevention Prophylaxis provided Randomized controlled trial reduce reduced reduced risk reducing mortality reductions in review Risk of bias risk ratio robust SARS-CoV-2 pandemic SARS-CoV-2 virus searched secondary secondary outcome Secondary outcomes sequential analysis severe adverse events severe disease suggested tested the SARS-CoV-2 the SARS-CoV-2 virus treatment trial treatment trials Trial trial sequential analyses trial sequential analysis
[DOI] 10.1097/MJT.0000000000001402 PMC 바로가기 [Article Type] Meta-Analysis

Interventions for treatment of COVID-19: Second edition of a living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)

COVID-19 치료를 위한 중재: 메타 분석 및 시험 순차 분석이 포함된 살아있는 체계적인 검토의 두 번째 판(The LIVING 프로젝트)

Meta-Analysis

Published on 2021-03-112022-08-13
Journal: PLoS ONE [Category] Biochemistry, SARS, 임상, 진단, 치료제,

[키워드] 95% CI 95% confidence interval adjusted Admission aggregate data meta-analyses all age group all age groups all-cause mortality Analysis boundary bromhexine caused certainty certainty of evidence Clinical research Clinical significance Cochrane guidelines comparison Comparisons Corticosteroid Corticosteroids COVID-19 database Effect Effects eight events Evidence evidence of Families FIVE Fixed-effect meta-analysis futility GRADE high risk Hydroxychloroquine Immunoglobulin indicate indication indications individual patient data meta-analyses individuals information intensive care Intervention effects intravenous Intravenous immunoglobulin lack life Lopinavir Lopinavir-ritonavir mechanical ventilation meta-analyses Meta-analysis moderate Network meta-analysis no evidence of non-serious adverse non-serious adverse events on mechanical ventilation outcome outcomes participant Participants patient data performed Primary outcomes PRISMA Quality of life random error random errors random-effects meta-analyses randomized clinical trial randomized clinical trials rapidly spreading disease reached reduce reduced Remdesivir renal replacement therapy replacement therapy required Research risk risk of death risk ratio risks of bia Ritonavir searched second secondary Secondary outcomes sequential analysis Serious Adverse Event Serious Adverse Events single trial standard care statistically significant systematic review threshold Tocilizumab Treatment treatment for COVID-19 treatment intervention treatments of COVID-19 Trial Trial methodology trial sequential analyses trial sequential analysis website with COVID-19
[DOI] 10.1371/journal.pone.0248132 PMC 바로가기 [Article Type] Meta-Analysis

Vaccines to prevent COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING VACCINE Project)

코로나19 예방 백신: 개별 환자 데이터를 포함하는 네트워크 메타 분석을 통한 살아있는 체계적인 검토를 위한 프로토콜(The LIVING VACCINE Project)

Protocol

Published on 2020-11-202022-09-10
Journal: Systematic Reviews [Category] COVID-19, meta-analysis, SARS,

[키워드] active placebo acute respiratory syndrome acute respiratory syndrome coronavirus aggregate data meta-analyses all age groups all-cause mortality analyzed approach assessment assessments best cause CENTRAL certainty certainty of evidence Clinical research clinical trial registries clinical trial registry clinical trials confidence coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 database dendritic dendritic cell described development Diagnosis disease Effect events Evidence GRADE identify inactivated include individual patient data meta-analyses life Messenger RNA meta-analyses Mortality network Network meta-analysis non-serious adverse non-serious adverse events not limited observational studies observational study once a week outcome pandemic participant patient data Placebo prevalent Prevent Primary outcomes Protein Protein subunit protocol Quality of life randomized clinical trial randomized clinical trials Research respiratory risk of bia SARS-CoV-2 secondary Secondary outcomes Serious Adverse Events severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Spread standard care supplementary material systematic review Trial trial sequential analyses Vaccine vaccine for COVID-19 Vaccines Viral Viral vector
[DOI] 10.1186/s13643-020-01516-1 PMC 바로가기 [Article Type] Protocol

Interventions for treatment of COVID-19: A living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)

COVID-19 치료를 위한 중재: 메타 분석 및 시험 순차 분석을 통한 살아있는 체계적인 검토(The LIVING Project)

Research Article

Published on 2020-09-172022-08-13
Journal: PLoS Medicine [Category] Biochemistry, COVID-19, SARS,

[키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus Admission adverse event adverse events aggregate data meta-analyses all age group all age groups all-cause mortality assessment caused certainty certainty of evidence Clinical effect Clinical research Clinical significance clinical trials Cochrane guidelines Comparisons conducted convalescent plasma coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients database development Dexamethasone driven by Effect Evidence evidence of experimental intervention Families GRADE high risk Hydroxychloroquine individual patient data meta-analyses individuals Infection intensive care International Intervention Intervention effects item Juul lack life Lopinavir Lopinavir–ritonavir mechanical ventilation meta-analyses Meta-analysis Network meta-analysis no effect no effects no evidence of nonserious adverse event nonserious adverse events on mechanical ventilation outbreak outcome outcomes participant Participants Patient patient data paucity of data performed Placebo Primary outcomes Quality of life random errors random-effects meta-analyses randomized clinical trial randomized clinical trials rapidly spreading disease rate ratio reduce reduced reducing Remdesivir renal replacement therapy replacement therapy Reporting Research researcher respiratory Respiratory failure review risk risk of bia risk of death risk ratio Ritonavir SARS-CoV-2 searched secondary Secondary outcomes Serious Adverse Event Serious Adverse Events severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 single trial single trial randomizing Sophie Spread standard care statistically significant systematic review systematic reviews Treatment treatment for COVID-19 treatment intervention treatment of COVID-19 treatments for COVID-19 treatments of COVID-19 Trial Trial methodology trial randomizing trial sequential analyses trial sequential analysis website with COVID-19
[DOI] 10.1371/journal.pmed.1003293 PMC 바로가기 [Article Type] Research Article