Pneumonia vaccine response in individuals with Down syndrome at three specialty clinicsarticle Published on 2023-12-312024-09-01 Journal: American Journal of Medical Genetics Part C: Seminars in Medical Genetics [Category] 폐렴구균 감염증, [키워드] Down syndrome Pneumonia trisomy 21 vaccination [Article Type] article
Enhancing understanding of SARS-CoV-2 infection among individuals with Down syndrome: An integrative reviewarticle Published on 2023-08-212024-09-05 Journal: São Paulo Medical Journal [Category] update2024, [키워드] Coronavirus disease 2019 COVID-19 Cytokine storm in coronavirus disease 2019 Down syndrome Down syndrome comorbidities integrative review Outcomes of coronavirus disease 2019 in individuals with Down syndrome SARS-CoV-2 Systematic review [publication type] trisomy 21 [DOI] 10.1590/1516-3180.2023.0015.R1.230523 PMC 바로가기 [Article Type] article
Will SARS-COV-2 infection accelerate the incidence of Alzheimer’s disease in Down syndrome population?Article Published on 2022-11-012023-07-10 Journal: Aging Clinical and Experimental Research [Category] COVID19(2023년), [키워드] Alzheimer's disease Dementia Infection hypothesis SARS-CoV-2 trisomy 21 [DOI] 10.1007/s40520-022-02280-z PMC 바로가기
Mechanistic Analysis of Age-Related Clinical Manifestations in Down SyndromeNeuroscience Published on 2021-07-012022-10-31 Journal: Frontiers in Aging Neuroscience [Category] COVID-19, [키워드] Abnormalities abnormality age Alzheimer’s disease Alzheimer’s disease Amino acid app Brain C-terminal Characteristics chromosome 21 clinical clinical manifestation COVID-19 Dementia disease dose Down syndrome Evidence facial facilitate Features genetic cause growth hearing loss immune system Impact Infection interferon pathway manifestation mechanism mechanisms modify pathology phenotype plaque severity of COVID-19 therapeutic intervention trisomy trisomy 21 [DOI] 10.3389/fnagi.2021.700280 PMC 바로가기 [Article Type] Neuroscience
Medical vulnerability of individuals with Down syndrome to severe COVID-19–data from the Trisomy 21 Research Society and the UK ISARIC4C surveyResearch article Published on 2021-03-012022-10-05 Journal: EClinicalMedicine [Category] 유전자 메커니즘, [키워드] Action addition age analysed Clinical course clinician collected Complication conditions congenital heart defect cough COVID-19 COVID-19 mortality COVID-19 patient disability Down syndrome Factor Fever finding foundation funding General population group Hospitalization hospitalized COVID-19 patient immune dysfunction individual initiative Intellectual International ISARIC4C Jerome leading less Medical vulnerability Mortality nausea Pain Patient patients with COVID-19 Premature rapid increase risk risk factor severe disease course Shortness of breath significantly higher Society symptoms of COVID-19 trisomy 21 vomiting [DOI] 10.1016/j.eclinm.2021.100769 [Article Type] Research article
Individuals with Down syndrome hospitalized with COVID-19 have more severe diseaseResearch article Published on 2021-03-012022-10-05 Journal: Genetics in medicine : official journal of the Ame [Category] 유전자 메커니즘, [키워드] Affect Analysis analyzed anomalies average Care center Clinical characteristics Columbia University condition controls COVID-19 COVID-19 pandemic Down syndrome Genetic Hospitalization Hospitalized incidence individual mechanical ventilation Mortality Mount Sinai New York outcomes Patient patients patients hospitalized Primary Immunodeficiency Result retrospective SARS-CoV-2 Sepsis severe disease System Treatment trisomy 21 USA with COVID-19 [DOI] 10.1038/s41436-020-01004-w [Article Type] Research article
Pneumonia and respiratory infections in Down syndrome: A scoping review of the literatureReview Published on 2021-01-012023-07-06 Journal: American journal of medical genetics. Part A [Category] SARS, [키워드] Down syndrome Pneumonia respiratory trisomy 21 [DOI] 10.1002/ajmg.a.61924 [Article Type] Review
COVID-19 and children with Down syndrome: is there any real reason to worry? Two case reports with severe courseCase Report Published on 2020-12-182022-10-28 Journal: BMC Pediatrics [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome addition amplified anomalies antiviral response Bergamo Case report caused characterized children chromosome 21 Comorbidities coronavirus coronavirus disease Course COVID-19 COVID-19 diagnosis Cytokine storm Down syndrome Hyperreactivity immune immune regulator interferon involved obesity observation obstructive sleep apnea pediatric responsible risk risk factor SARS-CoV-2 severe COVID-19 disease trisomy 21 [DOI] 10.1186/s12887-020-02471-5 PMC 바로가기 [Article Type] Case Report
Quantitative, Phenotypical, and Functional Characterization of Cellular Immunity in Children and Adolescents With Down SyndromeArticle Published on 2017-05-152023-06-02 Journal: The Journal of Infectious Diseases [Category] 두창, 홍역, [키워드] cellular immunity Down syndrome immunodeficiency disorders. trisomy 21 [DOI] 10.1093/infdis/jix168